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Predicting non-alcoholic fatty liver disease (NAFLD) using machine learning algorithms: Evidence from a large-scale community cohort in Taiwan.

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Title: Predicting non-alcoholic fatty liver disease (NAFLD) using machine learning algorithms: Evidence from a large-scale community cohort in Taiwan.
Authors: Lin TC; Hepatobiliary Division, Department of Internal Medicine, Center for Liquid Biopsy and Cohort Research, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan., Wei YJ; Hepatobiliary Division, Department of Internal Medicine, Center for Liquid Biopsy and Cohort Research, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan., Liang PC; Hepatobiliary Division, Department of Internal Medicine, Center for Liquid Biopsy and Cohort Research, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan., Tsai PC; Hepatobiliary Division, Department of Internal Medicine, Center for Liquid Biopsy and Cohort Research, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan., Lin YH; Hepatobiliary Division, Department of Internal Medicine, Center for Liquid Biopsy and Cohort Research, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan., Hsieh MH; Hepatobiliary Division, Department of Internal Medicine, Center for Liquid Biopsy and Cohort Research, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan.; Health Management Center, Department of Occupational and Environmental Medicine, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan., Jang TY; Hepatobiliary Division, Department of Internal Medicine, Center for Liquid Biopsy and Cohort Research, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan.; College of Medicine, Drug Development and Value Creation Research Center, Center for Metabolic Disorders and Obesity, Kaohsiung Medical University, Kaohsiung, Taiwan., Wang CW; Hepatobiliary Division, Department of Internal Medicine, Center for Liquid Biopsy and Cohort Research, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan.; College of Medicine, Drug Development and Value Creation Research Center, Center for Metabolic Disorders and Obesity, Kaohsiung Medical University, Kaohsiung, Taiwan., Hsieh MY; Hepatobiliary Division, Department of Internal Medicine, Center for Liquid Biopsy and Cohort Research, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan.; Department of Internal Medicine, Gangshan Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan., Lin ZY; Hepatobiliary Division, Department of Internal Medicine, Center for Liquid Biopsy and Cohort Research, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan.; College of Medicine, Drug Development and Value Creation Research Center, Center for Metabolic Disorders and Obesity, Kaohsiung Medical University, Kaohsiung, Taiwan., Yeh ML; Hepatobiliary Division, Department of Internal Medicine, Center for Liquid Biopsy and Cohort Research, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan.; Health Management Center, Department of Occupational and Environmental Medicine, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan.; College of Medicine, Drug Development and Value Creation Research Center, Center for Metabolic Disorders and Obesity, Kaohsiung Medical University, Kaohsiung, Taiwan.; School of Medicine and Doctoral Program of Clinical and Experimental Medicine, College of Medicine and Center of Excellence for Metabolic Associated Fatty Liver Disease, National Sun Yat-sen University, Kaohsiung, Taiwan., Huang JF; Hepatobiliary Division, Department of Internal Medicine, Center for Liquid Biopsy and Cohort Research, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan.; College of Medicine, Drug Development and Value Creation Research Center, Center for Metabolic Disorders and Obesity, Kaohsiung Medical University, Kaohsiung, Taiwan., Huang CF; Hepatobiliary Division, Department of Internal Medicine, Center for Liquid Biopsy and Cohort Research, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan.; College of Medicine, Drug Development and Value Creation Research Center, Center for Metabolic Disorders and Obesity, Kaohsiung Medical University, Kaohsiung, Taiwan., Chuang WL; Hepatobiliary Division, Department of Internal Medicine, Center for Liquid Biopsy and Cohort Research, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan.; College of Medicine, Drug Development and Value Creation Research Center, Center for Metabolic Disorders and Obesity, Kaohsiung Medical University, Kaohsiung, Taiwan., Yu ML; Hepatobiliary Division, Department of Internal Medicine, Center for Liquid Biopsy and Cohort Research, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan.; Health Management Center, Department of Occupational and Environmental Medicine, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan.; College of Medicine, Drug Development and Value Creation Research Center, Center for Metabolic Disorders and Obesity, Kaohsiung Medical University, Kaohsiung, Taiwan., Dai CY; Hepatobiliary Division, Department of Internal Medicine, Center for Liquid Biopsy and Cohort Research, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan.; Health Management Center, Department of Occupational and Environmental Medicine, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan.; College of Medicine, Drug Development and Value Creation Research Center, Center for Metabolic Disorders and Obesity, Kaohsiung Medical University, Kaohsiung, Taiwan.; Department of Internal Medicine, Gangshan Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan.; College of Professional Studies, National Pingtung University of Science and Technology, Pingtung, Taiwan., Shi HY; Department of Healthcare Administration and Medical Informatics, Kaohsiung Medical University, Kaohsiung, Taiwan.; Master of Health Care Management, Department of Business Management, National Sun Yat-sen University, Kaohsiung, Taiwan.; Department of Medical Research, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan.; Department of Medical Research, China Medical University Hospital, China Medical University, Taichung, Taiwan.
Source: Bioscience trends [Biosci Trends] 2026 Mar 04; Vol. 20 (1), pp. 80-90. Date of Electronic Publication: 2026 Feb 27.
Publication Type: Journal Article
Journal Info: Publisher: International Research and Cooperation Association for Bio & Socio-Sciences Advancement Country of Publication: Japan NLM ID: 101502754 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1881-7823 (Electronic) Linking ISSN: 18817815 NLM ISO Abbreviation: Biosci Trends Subsets: MEDLINE
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  Data: Predicting non-alcoholic fatty liver disease (NAFLD) using machine learning algorithms: Evidence from a large-scale community cohort in Taiwan.
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  Data: <searchLink fieldCode="AU" term="%22Lin+TC%22">Lin TC</searchLink>; Hepatobiliary Division, Department of Internal Medicine, Center for Liquid Biopsy and Cohort Research, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan.<br /><searchLink fieldCode="AU" term="%22Wei+YJ%22">Wei YJ</searchLink>; Hepatobiliary Division, Department of Internal Medicine, Center for Liquid Biopsy and Cohort Research, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan.<br /><searchLink fieldCode="AU" term="%22Liang+PC%22">Liang PC</searchLink>; Hepatobiliary Division, Department of Internal Medicine, Center for Liquid Biopsy and Cohort Research, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan.<br /><searchLink fieldCode="AU" term="%22Tsai+PC%22">Tsai PC</searchLink>; Hepatobiliary Division, Department of Internal Medicine, Center for Liquid Biopsy and Cohort Research, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan.<br /><searchLink fieldCode="AU" term="%22Lin+YH%22">Lin YH</searchLink>; Hepatobiliary Division, Department of Internal Medicine, Center for Liquid Biopsy and Cohort Research, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan.<br /><searchLink fieldCode="AU" term="%22Hsieh+MH%22">Hsieh MH</searchLink>; Hepatobiliary Division, Department of Internal Medicine, Center for Liquid Biopsy and Cohort Research, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan.; Health Management Center, Department of Occupational and Environmental Medicine, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan.<br /><searchLink fieldCode="AU" term="%22Jang+TY%22">Jang TY</searchLink>; Hepatobiliary Division, Department of Internal Medicine, Center for Liquid Biopsy and Cohort Research, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan.; College of Medicine, Drug Development and Value Creation Research Center, Center for Metabolic Disorders and Obesity, Kaohsiung Medical University, Kaohsiung, Taiwan.<br /><searchLink fieldCode="AU" term="%22Wang+CW%22">Wang CW</searchLink>; Hepatobiliary Division, Department of Internal Medicine, Center for Liquid Biopsy and Cohort Research, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan.; College of Medicine, Drug Development and Value Creation Research Center, Center for Metabolic Disorders and Obesity, Kaohsiung Medical University, Kaohsiung, Taiwan.<br /><searchLink fieldCode="AU" term="%22Hsieh+MY%22">Hsieh MY</searchLink>; Hepatobiliary Division, Department of Internal Medicine, Center for Liquid Biopsy and Cohort Research, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan.; Department of Internal Medicine, Gangshan Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan.<br /><searchLink fieldCode="AU" term="%22Lin+ZY%22">Lin ZY</searchLink>; Hepatobiliary Division, Department of Internal Medicine, Center for Liquid Biopsy and Cohort Research, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan.; College of Medicine, Drug Development and Value Creation Research Center, Center for Metabolic Disorders and Obesity, Kaohsiung Medical University, Kaohsiung, Taiwan.<br /><searchLink fieldCode="AU" term="%22Yeh+ML%22">Yeh ML</searchLink>; Hepatobiliary Division, Department of Internal Medicine, Center for Liquid Biopsy and Cohort Research, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan.; Health Management Center, Department of Occupational and Environmental Medicine, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan.; College of Medicine, Drug Development and Value Creation Research Center, Center for Metabolic Disorders and Obesity, Kaohsiung Medical University, Kaohsiung, Taiwan.; School of Medicine and Doctoral Program of Clinical and Experimental Medicine, College of Medicine and Center of Excellence for Metabolic Associated Fatty Liver Disease, National Sun Yat-sen University, Kaohsiung, Taiwan.<br /><searchLink fieldCode="AU" term="%22Huang+JF%22">Huang JF</searchLink>; Hepatobiliary Division, Department of Internal Medicine, Center for Liquid Biopsy and Cohort Research, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan.; College of Medicine, Drug Development and Value Creation Research Center, Center for Metabolic Disorders and Obesity, Kaohsiung Medical University, Kaohsiung, Taiwan.<br /><searchLink fieldCode="AU" term="%22Huang+CF%22">Huang CF</searchLink>; Hepatobiliary Division, Department of Internal Medicine, Center for Liquid Biopsy and Cohort Research, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan.; College of Medicine, Drug Development and Value Creation Research Center, Center for Metabolic Disorders and Obesity, Kaohsiung Medical University, Kaohsiung, Taiwan.<br /><searchLink fieldCode="AU" term="%22Chuang+WL%22">Chuang WL</searchLink>; Hepatobiliary Division, Department of Internal Medicine, Center for Liquid Biopsy and Cohort Research, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan.; College of Medicine, Drug Development and Value Creation Research Center, Center for Metabolic Disorders and Obesity, Kaohsiung Medical University, Kaohsiung, Taiwan.<br /><searchLink fieldCode="AU" term="%22Yu+ML%22">Yu ML</searchLink>; Hepatobiliary Division, Department of Internal Medicine, Center for Liquid Biopsy and Cohort Research, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan.; Health Management Center, Department of Occupational and Environmental Medicine, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan.; College of Medicine, Drug Development and Value Creation Research Center, Center for Metabolic Disorders and Obesity, Kaohsiung Medical University, Kaohsiung, Taiwan.<br /><searchLink fieldCode="AU" term="%22Dai+CY%22">Dai CY</searchLink>; Hepatobiliary Division, Department of Internal Medicine, Center for Liquid Biopsy and Cohort Research, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan.; Health Management Center, Department of Occupational and Environmental Medicine, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan.; College of Medicine, Drug Development and Value Creation Research Center, Center for Metabolic Disorders and Obesity, Kaohsiung Medical University, Kaohsiung, Taiwan.; Department of Internal Medicine, Gangshan Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan.; College of Professional Studies, National Pingtung University of Science and Technology, Pingtung, Taiwan.<br /><searchLink fieldCode="AU" term="%22Shi+HY%22">Shi HY</searchLink>; Department of Healthcare Administration and Medical Informatics, Kaohsiung Medical University, Kaohsiung, Taiwan.; Master of Health Care Management, Department of Business Management, National Sun Yat-sen University, Kaohsiung, Taiwan.; Department of Medical Research, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan.; Department of Medical Research, China Medical University Hospital, China Medical University, Taichung, Taiwan.
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  Data: <searchLink fieldCode="JN" term="%22101502754%22">Bioscience trends</searchLink> [Biosci Trends] 2026 Mar 04; Vol. 20 (1), pp. 80-90. <i>Date of Electronic Publication: </i>2026 Feb 27.
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