Interleukin-1β downregulates K+ currents through Kv1.6 channels and promotes apoptosis by enhancing Ca2+ influx in chondrocytes.
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| Title: | Interleukin-1β downregulates K+ currents through K |
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| Authors: | Kurata T; Department of Molecular and Cellular Pharmacology, Graduate School of Pharmaceutical Sciences, Nagoya City University, Nagoya, Aichi, Japan., Suzuki Y; Department of Molecular and Cellular Pharmacology, Graduate School of Pharmaceutical Sciences, Nagoya City University, Nagoya, Aichi, Japan., Tateno S; Department of Molecular and Cellular Pharmacology, Graduate School of Pharmaceutical Sciences, Nagoya City University, Nagoya, Aichi, Japan., Miyaki S; Medical Center for Translational and Clinical Research, Hiroshima University Hospital, Hiroshima, Japan., Kondo R; Department of Molecular and Cellular Pharmacology, Graduate School of Pharmaceutical Sciences, Nagoya City University, Nagoya, Aichi, Japan., Bernotiene E; Department of Regenerative Medicine, Innovative Medicine Center, Vilnius, Lithuania.; Faculty of Fundamental Sciences, Vilnius Gediminas Technical University, VilniusTech, Vilnius, Lithuania., Mobasheri A; Department of Regenerative Medicine, Innovative Medicine Center, Vilnius, Lithuania.; Research Unit of Health Sciences and Technology, Faculty of Medicine, University of Oulu, Oulu, Finland.; Department of Joint Surgery, First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.; Faculty of Medicine, Université de Liège, Liege, Belgium., Giles WR; Department of Physiology and Pharmacology, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada., Imaizumi Y; Department of Molecular and Cellular Pharmacology, Graduate School of Pharmaceutical Sciences, Nagoya City University, Nagoya, Aichi, Japan., Yamamura H; Department of Molecular and Cellular Pharmacology, Graduate School of Pharmaceutical Sciences, Nagoya City University, Nagoya, Aichi, Japan. |
| Source: | American journal of physiology. Cell physiology [Am J Physiol Cell Physiol] 2026 Apr 01; Vol. 330 (4), pp. C909-C925. Date of Electronic Publication: 2026 Mar 02. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: American Physiological Society Country of Publication: United States NLM ID: 100901225 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1522-1563 (Electronic) Linking ISSN: 03636143 NLM ISO Abbreviation: Am J Physiol Cell Physiol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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