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Influence of multiple trauma on the effect of transfusion strategies in patients with traumatic brain injury: a sub-study of the HEMOTION trial.

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Title: Influence of multiple trauma on the effect of transfusion strategies in patients with traumatic brain injury: a sub-study of the HEMOTION trial.
Authors: Bouras M; Centre Hospitalier Universitaire (CHU) de Québec-Université Laval Research Center, Population Health and Optimal Health Practices Research Unit (Trauma-Emergency-Critical Care Medicine), Quebec City, Canada.; Department of Anesthesiology and Critical Care Medicine, Division of Critical Care Medicine, Université Laval, Quebec City, Canada.; Department of Anesthesiology and Critical Care Medicine, Centre Hospitalier Régional Universitaire de Brest, Brest, France., Lauzier F; Centre Hospitalier Universitaire (CHU) de Québec-Université Laval Research Center, Population Health and Optimal Health Practices Research Unit (Trauma-Emergency-Critical Care Medicine), Quebec City, Canada.; Department of Anesthesiology and Critical Care Medicine, Division of Critical Care Medicine, Université Laval, Quebec City, Canada.; Department of Medicine, Faculty of Medicine, Université Laval, Quebec City, Canada., Fergusson DA; Ottawa Hospital Research Institute, Ottawa, Canada.; Faculty of Medicine, University of Ottawa, Ottawa, Canada.; School of Epidemiology and Public Health, University of Ottawa, Ottawa, Ontario, Canada., Neveu X; Centre Hospitalier Universitaire (CHU) de Québec-Université Laval Research Center, Population Health and Optimal Health Practices Research Unit (Trauma-Emergency-Critical Care Medicine), Quebec City, Canada., Clayton L; Centre Hospitalier Universitaire (CHU) de Québec-Université Laval Research Center, Population Health and Optimal Health Practices Research Unit (Trauma-Emergency-Critical Care Medicine), Quebec City, Canada.; Centre Hospitalier Universitaire Sainte-Justine, Université de Montréal, Montreal, Canada., Patton MP; Centre Hospitalier Universitaire (CHU) de Québec-Université Laval Research Center, Population Health and Optimal Health Practices Research Unit (Trauma-Emergency-Critical Care Medicine), Quebec City, Canada., Costerousse O; Centre Hospitalier Universitaire (CHU) de Québec-Université Laval Research Center, Population Health and Optimal Health Practices Research Unit (Trauma-Emergency-Critical Care Medicine), Quebec City, Canada., English SW; Ottawa Hospital Research Institute, Ottawa, Canada.; Faculty of Medicine, University of Ottawa, Ottawa, Canada.; School of Epidemiology and Public Health, University of Ottawa, Ottawa, Ontario, Canada., Docherty A; Usher Institute of Population Health Sciences, Edinburgh Medical School, University of Edinburgh, Edinburgh, UK.; Department of Anaesthesia, Critical Care and Pain Medicine, Edinburgh Medical School, University of Edinburgh, Edinburgh, UK., Malbouisson LMS; Surgical Intensive Care Unit, Anesthesiology Division, Hospital das Clínicas, University of São Paulo Medical School, São Paulo, Brazil., Zarychanski R; Department of Internal Medicine, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, Canada.; Department of Medical Oncology/Haematology, The Paul Albrechtsen Research Institute, CancerCare Manitoba, Winnipeg, Canada., Moore L; Department of Anesthesiology and Critical Care Medicine, Division of Critical Care Medicine, Université Laval, Quebec City, Canada.; Department of Social and Preventive Medicine, Faculty of Medicine, Université Laval, Quebec City, Canada., Lessard Bonaventure P; Department of Anesthesiology and Critical Care Medicine, Division of Critical Care Medicine, Université Laval, Quebec City, Canada.; Department of Surgery, Division of Neurosurgery, Faculty of Medicine, Université Laval, Quebec City, Canada., Laroche V; Centre Hospitalier Universitaire (CHU) de Québec-Université Laval Research Center, Population Health and Optimal Health Practices Research Unit (Trauma-Emergency-Critical Care Medicine), Quebec City, Canada.; Department of Medicine, Faculty of Medicine, Université Laval, Quebec City, Canada., Verret M; Centre Hospitalier Universitaire (CHU) de Québec-Université Laval Research Center, Population Health and Optimal Health Practices Research Unit (Trauma-Emergency-Critical Care Medicine), Quebec City, Canada.; Department of Anesthesiology and Critical Care Medicine, Division of Critical Care Medicine, Université Laval, Quebec City, Canada., Scales DC; Department of Critical Care Medicine, Sunnybrook Health Sciences Center and Sunnybrook Research Institute, Toronto, Canada.; Interdepartmental Division of Critical Care Medicine, University of Toronto, Toronto, Canada., Adhikari NKJ; Department of Critical Care Medicine, Sunnybrook Health Sciences Center and Sunnybrook Research Institute, Toronto, Canada.; Interdepartmental Division of Critical Care Medicine, University of Toronto, Toronto, Canada., Greenbaum J; Salford Royal Hospital, Northern Care Alliance NHS Foundation Trust, Salford, UK., Kramer A; Departments of Critical Care Medicine and Clinical Neurosciences, Hotchkiss Brain Institute, University of Calgary, Calgary, Canada., Garnelo Rey V; St Mary's Hospital, Imperial College Healthcare NHS Trust, London, UK., Ball I; Department of Medicine and Department of Epidemiology and Biostatistics, Western University, London, Canada., Khwaja K; Departments of Surgery and Critical Care Medicine, McGill University Health Centre, Montreal, Canada., Wise M; Cardiff University, Cardiff, UK.; University of Wales Hospital, Cardiff, UK., Harvey D; Nottingham University Hospitals NHS Trust, Nottingham, UK., Chabanne R; Département Anesthésie Réanimation Et Médecine Périopératoire, Centre Hospitalier Universitaire (CHU) de Clermont-Ferrand, Clermont-Ferrand, France., Pottecher J; Hôpital de Hautepierre, Service d'Anesthésie-Réanimation Et Médecine Péri-Opératoire, Hôpitaux Universitaires de Strasbourg, Strasbourg, France., Rhodes J; Usher Institute of Population Health Sciences, Edinburgh Medical School, University of Edinburgh, Edinburgh, UK., Rigamonti A; Interdepartmental Division of Critical Care Medicine, University of Toronto, Toronto, Canada.; Department of Anesthesia, St. Michael's Hospital, University of Toronto, Toronto, Canada., Burns KEA; Interdepartmental Division of Critical Care Medicine, University of Toronto, Toronto, Canada.; Applied Health Research Centre, Li Ka Shing Knowledge Institute, Unity Health Toronto-St. Michael's Hospital, Toronto, Canada.; Departments of Medicine and Health Research Methods, Evidence and Impact, McMaster University, Hamilton, Canada.; Department of Critical Care, Unity Health Toronto-St. Michael's Hospital, Toronto, Canada., Griesdale DE; Department of Medicine, Division of Critical Care Medicine, Faculty of Medicine, Vancouver General Hospital, University of British Columbia, Vancouver, Canada., Kutsogiannis DJ; Department of Critical Care Medicine, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Canada., Green R; Trauma Nova Scotia, Nova Scotia Health, Halifax, Canada.; Departments of Critical Care, Emergency Medicine, Anesthesia and Surgery, Dalhousie University, Halifax, Canada., Boyd JG; Department of Medicine, Division of Neurology, School of Medicine, Queen's University, Kingston, Canada.; Department of Critical Care Medicine, School of Medicine, Queen's University, Kingston, Canada., Zeiler F; Biomedical Engineering, Faculty of Engineering, University of Manitoba, Winnipeg, Canada.; Department of Human Anatomy and Cell Science, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, Canada.; Department of Surgery, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, Canada., Gomez A; Department of Human Anatomy and Cell Science, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, Canada.; Department of Surgery, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, Canada., Charbonney E; Department of Medicine, Centre Hospitalier de l'Université de Montréal (CHUM), Montreal, Canada.; Department of Medicine, Faculty of Medicine, Université de Montréal, Montreal, Canada.; Centre Intégré Universitaire de Santé et de Services Sociaux (CIUSSS) de la Mauricie-et-du-Centre-du-Québec, Trois-Rivières, Canada., Astles T; Department of Intensive Care Medicine, Liverpool University Hospitals NHS, Liverpool, UK., Sy E; College of Medicine, University of Saskatchewan, Regina, Canada.; Saskatchewan Health Authority-Regina Area, Regina, Canada., Turgeon AF; Centre Hospitalier Universitaire (CHU) de Québec-Université Laval Research Center, Population Health and Optimal Health Practices Research Unit (Trauma-Emergency-Critical Care Medicine), Quebec City, Canada. alexis.turgeon@crchudequebec.ulaval.ca.; Department of Anesthesiology and Critical Care Medicine, Division of Critical Care Medicine, Université Laval, Quebec City, Canada. alexis.turgeon@crchudequebec.ulaval.ca.
Corporate Authors: HEMOTION Trial investigators, the Canadian Critical Care Trials Group, the Canadian Perioperative Anesthesia Clinical Trials Group, the Canadian Traumatic Brain Injury Research Consortium
Source: Intensive care medicine [Intensive Care Med] 2026 Feb; Vol. 52 (2), pp. 211-229. Date of Electronic Publication: 2026 Mar 03.
Publication Type: Journal Article; Randomized Controlled Trial
Journal Info: Publisher: Springer Verlag Country of Publication: United States NLM ID: 7704851 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-1238 (Electronic) Linking ISSN: 03424642 NLM ISO Abbreviation: Intensive Care Med Subsets: MEDLINE
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  Data: Influence of multiple trauma on the effect of transfusion strategies in patients with traumatic brain injury: a sub-study of the HEMOTION trial.
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  Data: <searchLink fieldCode="AU" term="%22Bouras+M%22">Bouras M</searchLink>; Centre Hospitalier Universitaire (CHU) de Québec-Université Laval Research Center, Population Health and Optimal Health Practices Research Unit (Trauma-Emergency-Critical Care Medicine), Quebec City, Canada.; Department of Anesthesiology and Critical Care Medicine, Division of Critical Care Medicine, Université Laval, Quebec City, Canada.; Department of Anesthesiology and Critical Care Medicine, Centre Hospitalier Régional Universitaire de Brest, Brest, France.<br /><searchLink fieldCode="AU" term="%22Lauzier+F%22">Lauzier F</searchLink>; Centre Hospitalier Universitaire (CHU) de Québec-Université Laval Research Center, Population Health and Optimal Health Practices Research Unit (Trauma-Emergency-Critical Care Medicine), Quebec City, Canada.; Department of Anesthesiology and Critical Care Medicine, Division of Critical Care Medicine, Université Laval, Quebec City, Canada.; Department of Medicine, Faculty of Medicine, Université Laval, Quebec City, Canada.<br /><searchLink fieldCode="AU" term="%22Fergusson+DA%22">Fergusson DA</searchLink>; 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Cardiff University, Cardiff, UK.; University of Wales Hospital, Cardiff, UK.<br /><searchLink fieldCode="AU" term="%22Harvey+D%22">Harvey D</searchLink>; Nottingham University Hospitals NHS Trust, Nottingham, UK.<br /><searchLink fieldCode="AU" term="%22Chabanne+R%22">Chabanne R</searchLink>; Département Anesthésie Réanimation Et Médecine Périopératoire, Centre Hospitalier Universitaire (CHU) de Clermont-Ferrand, Clermont-Ferrand, France.<br /><searchLink fieldCode="AU" term="%22Pottecher+J%22">Pottecher J</searchLink>; Hôpital de Hautepierre, Service d'Anesthésie-Réanimation Et Médecine Péri-Opératoire, Hôpitaux Universitaires de Strasbourg, Strasbourg, France.<br /><searchLink fieldCode="AU" term="%22Rhodes+J%22">Rhodes J</searchLink>; Usher Institute of Population Health Sciences, Edinburgh Medical School, University of Edinburgh, Edinburgh, UK.<br /><searchLink fieldCode="AU" term="%22Rigamonti+A%22">Rigamonti A</searchLink>; Interdepartmental Division of Critical Care Medicine, University of Toronto, Toronto, Canada.; 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            – Type: issue
              Value: 2
          Titles:
            – TitleFull: Intensive care medicine
              Type: main
ResultId 1