Semaglutide Effects on Insulin Sensitivity and β-Cell Function in Patients With Schizophrenia, Prediabetes, and Obesity Treated With Second-Generation Antipsychotics: Findings From the HISTORI Trial, a 30-Week Randomized, Placebo-Controlled Trial With Semaglutide 1.0 mg Weekly.

Saved in:
Bibliographic Details
Title: Semaglutide Effects on Insulin Sensitivity and β-Cell Function in Patients With Schizophrenia, Prediabetes, and Obesity Treated With Second-Generation Antipsychotics: Findings From the HISTORI Trial, a 30-Week Randomized, Placebo-Controlled Trial With Semaglutide 1.0 mg Weekly.
Authors: Ganeshalingam AA; Endocrine Research Unit, Department of Endocrinology, Odense University Hospital, Odense, Denmark.; Department of Clinical Research, Faculty of Health Science, University of Southern Denmark, Odense, Denmark.; Steno Diabetes Center Odense, Odense University Hospital, Odense, Denmark., Uhrenholt N; Department of Clinical Research, Faculty of Health Science, University of Southern Denmark, Odense, Denmark.; Research Unit for Clinical Psychopharmacology, Psychiatry West in Region Zealand, Slagelse, Denmark.; Child and Adolescent Psychiatry Odense, Mental Health Services in the Region of Southern Denmark, Odense, Denmark.; Psychiatric Research Unit, Copenhagen University Hospital-Psychiatry Region Zealand, Slagelse, Denmark., Arnfred S; Psychiatric Research Unit, Copenhagen University Hospital-Psychiatry Region Zealand, Slagelse, Denmark.; Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark., Gæde P; Department of Internal Medicine, Geriatrics and Neurology, Næstved, Slagelse og Ringsted Sygehuse, Slagelse, Denmark.; IRS-Department of Regional Health Research, Faculty of Health Science, University of Southern Denmark, Odense, Denmark., Pedersen AK; OUH, OPEN-Open Patient Data Explorative Network (Odense), Odense, Denmark., Bilenberg N; Department of Clinical Research, Faculty of Health Science, University of Southern Denmark, Odense, Denmark.; Child and Adolescent Psychiatry Odense, Mental Health Services in the Region of Southern Denmark, Odense, Denmark., Frystyk J; Endocrine Research Unit, Department of Endocrinology, Odense University Hospital, Odense, Denmark.; Department of Clinical Research, Faculty of Health Science, University of Southern Denmark, Odense, Denmark.; Steno Diabetes Center Odense, Odense University Hospital, Odense, Denmark.
Source: Diabetes care [Diabetes Care] 2026 May 01; Vol. 49 (5), pp. 800-807.
Publication Type: Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
Journal Info: Publisher: American Diabetes Association Country of Publication: United States NLM ID: 7805975 Publication Model: Print Cited Medium: Internet ISSN: 1935-5548 (Electronic) Linking ISSN: 01495992 NLM ISO Abbreviation: Diabetes Care Subsets: MEDLINE
Database: MEDLINE Ultimate
Full text is not displayed to guests.
FullText Links:
  – Type: pdflink
Text:
  Availability: 1
Header DbId: mdl
DbLabel: MEDLINE Ultimate
An: 41778920
AccessLevel: 2
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Semaglutide Effects on Insulin Sensitivity and β-Cell Function in Patients With Schizophrenia, Prediabetes, and Obesity Treated With Second-Generation Antipsychotics: Findings From the HISTORI Trial, a 30-Week Randomized, Placebo-Controlled Trial With Semaglutide 1.0 mg Weekly.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AU" term="%22Ganeshalingam+AA%22">Ganeshalingam AA</searchLink>; Endocrine Research Unit, Department of Endocrinology, Odense University Hospital, Odense, Denmark.; Department of Clinical Research, Faculty of Health Science, University of Southern Denmark, Odense, Denmark.; Steno Diabetes Center Odense, Odense University Hospital, Odense, Denmark.<br /><searchLink fieldCode="AU" term="%22Uhrenholt+N%22">Uhrenholt N</searchLink>; Department of Clinical Research, Faculty of Health Science, University of Southern Denmark, Odense, Denmark.; Research Unit for Clinical Psychopharmacology, Psychiatry West in Region Zealand, Slagelse, Denmark.; Child and Adolescent Psychiatry Odense, Mental Health Services in the Region of Southern Denmark, Odense, Denmark.; Psychiatric Research Unit, Copenhagen University Hospital-Psychiatry Region Zealand, Slagelse, Denmark.<br /><searchLink fieldCode="AU" term="%22Arnfred+S%22">Arnfred S</searchLink>; Psychiatric Research Unit, Copenhagen University Hospital-Psychiatry Region Zealand, Slagelse, Denmark.; Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Gæde+P%22">Gæde P</searchLink>; Department of Internal Medicine, Geriatrics and Neurology, Næstved, Slagelse og Ringsted Sygehuse, Slagelse, Denmark.; IRS-Department of Regional Health Research, Faculty of Health Science, University of Southern Denmark, Odense, Denmark.<br /><searchLink fieldCode="AU" term="%22Pedersen+AK%22">Pedersen AK</searchLink>; OUH, OPEN-Open Patient Data Explorative Network (Odense), Odense, Denmark.<br /><searchLink fieldCode="AU" term="%22Bilenberg+N%22">Bilenberg N</searchLink>; Department of Clinical Research, Faculty of Health Science, University of Southern Denmark, Odense, Denmark.; Child and Adolescent Psychiatry Odense, Mental Health Services in the Region of Southern Denmark, Odense, Denmark.<br /><searchLink fieldCode="AU" term="%22Frystyk+J%22">Frystyk J</searchLink>; Endocrine Research Unit, Department of Endocrinology, Odense University Hospital, Odense, Denmark.; Department of Clinical Research, Faculty of Health Science, University of Southern Denmark, Odense, Denmark.; Steno Diabetes Center Odense, Odense University Hospital, Odense, Denmark.
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%227805975%22">Diabetes care</searchLink> [Diabetes Care] 2026 May 01; Vol. 49 (5), pp. 800-807.
– Name: TypePub
  Label: Publication Type
  Group: TypPub
  Data: Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
– Name: TitleSource
  Label: Journal Info
  Group: Src
  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Diabetes+Association%22">American Diabetes Association </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>7805975 <i>Publication Model: </i>Print <i>Cited Medium: </i>Internet <i>ISSN: </i>1935-5548 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2201495992%22">01495992 </searchLink><i>NLM ISO Abbreviation: </i>Diabetes Care <i>Subsets: </i>MEDLINE
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=41778920
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.2337/dc25-2041
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        StartPage: 800
    Titles:
      – TitleFull: Semaglutide Effects on Insulin Sensitivity and β-Cell Function in Patients With Schizophrenia, Prediabetes, and Obesity Treated With Second-Generation Antipsychotics: Findings From the HISTORI Trial, a 30-Week Randomized, Placebo-Controlled Trial With Semaglutide 1.0 mg Weekly.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Ganeshalingam AA
      – PersonEntity:
          Name:
            NameFull: Uhrenholt N
      – PersonEntity:
          Name:
            NameFull: Arnfred S
      – PersonEntity:
          Name:
            NameFull: Gæde P
      – PersonEntity:
          Name:
            NameFull: Pedersen AK
      – PersonEntity:
          Name:
            NameFull: Bilenberg N
      – PersonEntity:
          Name:
            NameFull: Frystyk J
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 01
              M: 05
              Text: 2026 May 01
              Type: published
              Y: 2026
          Identifiers:
            – Type: issn-electronic
              Value: 1935-5548
          Numbering:
            – Type: volume
              Value: 49
            – Type: issue
              Value: 5
          Titles:
            – TitleFull: Diabetes care
              Type: main
ResultId 1