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3D region-growing nnU-Net improves pulmonary embolism detection on CTPA: a dual-cohort validation study.

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Title: 3D region-growing nnU-Net improves pulmonary embolism detection on CTPA: a dual-cohort validation study.
Authors: Lanza E; Department of Biomedical Sciences, Humanitas University, Milan, Italy. ezio.lanza@humanitas.it.; Department of Diagnostic and Interventional Radiology, IRCCS Humanitas Research Hospital, Milan, Italy. ezio.lanza@humanitas.it., Ammirabile A; Department of Biomedical Sciences, Humanitas University, Milan, Italy.; Department of Diagnostic and Interventional Radiology, IRCCS Humanitas Research Hospital, Milan, Italy., Vanzulli A; Department of Biomedical Sciences, Humanitas University, Milan, Italy.; Diagnostic and Interventional Radiology Residency Program, Università degli Studi di Milano, Milan, Italy.; Department of Diagnostic and Interventional Radiology, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy., Lisi C; Department of Biomedical Sciences, Humanitas University, Milan, Italy.; Department of Diagnostic and Interventional Radiology, IRCCS Humanitas Research Hospital, Milan, Italy., Perera AS; Department of Biomedical Sciences, Humanitas University, Milan, Italy., Lucia AMA; Department of Biomedical Sciences, Humanitas University, Milan, Italy.; Department of Diagnostic and Interventional Radiology, IRCCS Humanitas Research Hospital, Milan, Italy., Mininni A; Department of Biomedical Sciences, Humanitas University, Milan, Italy.; Department of Diagnostic and Interventional Radiology, IRCCS Humanitas Research Hospital, Milan, Italy., Levi R; Department of Biomedical Sciences, Humanitas University, Milan, Italy.; Department of Diagnostic and Interventional Radiology, IRCCS Humanitas Research Hospital, Milan, Italy., Francone M; Department of Radiological, Oncological and Pathological Sciences, Sapienza University of Rome, Rome, Italy., Laghi A; Department of Biomedical Sciences, Humanitas University, Milan, Italy.; Department of Diagnostic and Interventional Radiology, IRCCS Humanitas Research Hospital, Milan, Italy.
Source: European radiology experimental [Eur Radiol Exp] 2026 Mar 04; Vol. 10 (1). Date of Electronic Publication: 2026 Mar 04.
Publication Type: Journal Article; Validation Study
Journal Info: Publisher: SpringerOpen Country of Publication: England NLM ID: 101721752 Publication Model: Electronic Cited Medium: Internet ISSN: 2509-9280 (Electronic) Linking ISSN: 25099280 NLM ISO Abbreviation: Eur Radiol Exp Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: 3D region-growing nnU-Net improves pulmonary embolism detection on CTPA: a dual-cohort validation study.
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  Data: <searchLink fieldCode="AU" term="%22Lanza+E%22">Lanza E</searchLink>; Department of Biomedical Sciences, Humanitas University, Milan, Italy. ezio.lanza@humanitas.it.; Department of Diagnostic and Interventional Radiology, IRCCS Humanitas Research Hospital, Milan, Italy. ezio.lanza@humanitas.it.<br /><searchLink fieldCode="AU" term="%22Ammirabile+A%22">Ammirabile A</searchLink>; Department of Biomedical Sciences, Humanitas University, Milan, Italy.; Department of Diagnostic and Interventional Radiology, IRCCS Humanitas Research Hospital, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Vanzulli+A%22">Vanzulli A</searchLink>; Department of Biomedical Sciences, Humanitas University, Milan, Italy.; Diagnostic and Interventional Radiology Residency Program, Università degli Studi di Milano, Milan, Italy.; Department of Diagnostic and Interventional Radiology, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Lisi+C%22">Lisi C</searchLink>; Department of Biomedical Sciences, Humanitas University, Milan, Italy.; Department of Diagnostic and Interventional Radiology, IRCCS Humanitas Research Hospital, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Perera+AS%22">Perera AS</searchLink>; Department of Biomedical Sciences, Humanitas University, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Lucia+AMA%22">Lucia AMA</searchLink>; Department of Biomedical Sciences, Humanitas University, Milan, Italy.; Department of Diagnostic and Interventional Radiology, IRCCS Humanitas Research Hospital, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Mininni+A%22">Mininni A</searchLink>; Department of Biomedical Sciences, Humanitas University, Milan, Italy.; Department of Diagnostic and Interventional Radiology, IRCCS Humanitas Research Hospital, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Levi+R%22">Levi R</searchLink>; Department of Biomedical Sciences, Humanitas University, Milan, Italy.; Department of Diagnostic and Interventional Radiology, IRCCS Humanitas Research Hospital, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Francone+M%22">Francone M</searchLink>; Department of Radiological, Oncological and Pathological Sciences, Sapienza University of Rome, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Laghi+A%22">Laghi A</searchLink>; Department of Biomedical Sciences, Humanitas University, Milan, Italy.; Department of Diagnostic and Interventional Radiology, IRCCS Humanitas Research Hospital, Milan, Italy.
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  Data: <searchLink fieldCode="JN" term="%22101721752%22">European radiology experimental</searchLink> [Eur Radiol Exp] 2026 Mar 04; Vol. 10 (1). <i>Date of Electronic Publication: </i>2026 Mar 04.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22SpringerOpen%22">SpringerOpen </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101721752 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2509-9280 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2225099280%22">25099280 </searchLink><i>NLM ISO Abbreviation: </i>Eur Radiol Exp <i>Subsets: </i>MEDLINE
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            – D: 04
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              Text: 2026 Mar 04
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