Comparison of first-line cetuximab and panitumumab plus doublet chemotherapies for left-sided colorectal cancer: a multicenter real-world observational study by the Japanese Society for Cancer of the Colon and Rectum.

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Title: Comparison of first-line cetuximab and panitumumab plus doublet chemotherapies for left-sided colorectal cancer: a multicenter real-world observational study by the Japanese Society for Cancer of the Colon and Rectum.
Authors: Kawagoe R; Department of Gastroenterology, Faculty of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, 305-8575, Japan., Moriwaki T; Department of Gastroenterology and Hepatology, Kurashiki Central Hospital, 1-1-1 Miwa, Kurashiki, 710-8602, Japan. tmoriwak@gmail.com., Yamazaki K; Division of Gastrointestinal Oncology, Shizuoka Cancer Center, 1007 Shimonagakubo, Suntou-gun, Nagaizumi-cho, Shizuoka, 411-8777, Japan., Yukami H; Department of Gastroenterology and Gastrointestinal Oncology, National Cancer Center Hospital East, 6-5-1 Kashiwanoha, Kashiwa, 277-8577, Japan.; Cancer Chemotherapy Center, Osaka Medical and Pharmaceutical University Hospital, 2-7 Daigaku-machi, Takatsuki, 569-8686, Japan., Uetake H; Department of Clinical Research, National Hospital Organization Disaster Medical Center, 3256 Midori-cho, Tachikawa, 190-0014, Japan., Tsuda M; Department of Gastroenterological Oncology, Hyogo Cancer Center, 13-70 Kitaouji-cho, Akashi, 673-8558, Japan., Suto T; Department of Gastroenterological Surgery, Yamagata Prefectural Central Hospital, 1800 Aoyagi, Yamagata, 990-2292, Japan., Sugimoto N; Department of Genetic Oncology, Osaka International Cancer Institute, 3-1-69 Otemae, Chuo-ku, Osaka, 541-8567, Japan., Ojima H; Department of Gastroenterological Surgery, Gunma Prefectural Cancer Center, 617-1 Takahayashi-nishi-cho, Ota, 373-8550, Japan., Takii Y; Department of Gastroenterological Surgery, Niigata Cancer Center Hospital, 2-15-3 Kawagishi-cho, Chuo-ku, Niigata, 951-8566, Japan., Yasui H; Department of Medical Oncology, Kobe City Medical Center General Hospital, 2-1-1 Minatojima-minami-machi, Chuo-ku, Kobe, 650-0047, Japan., Komoda M; Department of Gastrointestinal and Medical Oncology, National Hospital Organization Kyushu Cancer Center, 3-1-1 Notame, Minami-ku, Fukuoka, 811-1395, Japan., Shimada Y; Division of Clinical Oncology, Kochi Health Sciences Center, 2125-1 Ike, Kochi, 781-8555, Japan., Tsuji A; Department of Clinical Oncology, Kagawa University Faculty of Medicine, 1750-1 Ikenobe, Kita-gun, Miki-cho, Kagawa, 761-0793, Japan., Yamaguchi T; Cancer Chemotherapy Center, Osaka Medical and Pharmaceutical University Hospital, 2-7 Daigaku-machi, Takatsuki, 569-8686, Japan., Sawada R; Division of Gastroenterology and Hepatology, Department of Internal Medicine, The Jikei University School of Medicine, 3-19-18 Nishi-shinbashi, Minato-ku, Tokyo, 105-8471, Japan., Shinozaki K; Division of Clinical Oncology, Hiroshima Prefectural Hospital, 1-5-54 Ujinakanda, Minami-ku, Hiroshima, 734-8530, Japan., Otsu S; Department of Medical Oncology and Hematology, Oita University Faculty of Medicine, 1-1 Idaigaoka, Hasama-machi, Yufu, 879-5593, Japan., Shigeyasu K; Department of Gastroenterological Surgery, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, 2-5-1 Shikata-cho, Kita-ku, Okayama, 700-8558, Japan., Tsuchihashi K; Department of Hematology, Oncology and Cardiovascular Medicine, Kyushu University Hospital, 3-1-1 Maidashi, Higashi-ku, Fukuoka, 812-8582, Japan., Tamura T; Department of Medical Oncology, Kindai University Nara Hospital, 1248-1 Otoda-cho, Ikoma, 630-0293, Japan., Shiozawa M; Division of Gastrointestinal Surgery, Kanagawa Cancer Center, 2-3-2 Nakao, Asahi-ku, Yokohama, 241-8515, Japan., Ueno H; Department of Surgery, National Defense Medical College, 3-2 Namiki, Tokorozawa, 359-8513, Japan., Denda T; Division of Gastroenterology, Chiba Cancer Center, 666-2 Nitona-cho, Chuo-ku, Chiba, 260-8717, Japan., Ito T; Department of Gastroenterology, Japan Baptist Hospital, 47 Kitashirakawa-yamanomoto-cho, Sakyo-ku, Kyoto, 606-8273, Japan., Takashima A; Division of Gastrointestinal Medical Oncology, National Cancer Center Hospital, 5-1-1 Tsukiji, Chuo-ku, Tokyo, 104-0045, Japan.
Source: International journal of clinical oncology [Int J Clin Oncol] 2026 May; Vol. 31 (5), pp. 851-858. Date of Electronic Publication: 2026 Mar 04.
Publication Type: Journal Article; Multicenter Study; Observational Study; Comparative Study
Journal Info: Publisher: Springer-Verlag Tokyo Country of Publication: Japan NLM ID: 9616295 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1437-7772 (Electronic) Linking ISSN: 13419625 NLM ISO Abbreviation: Int J Clin Oncol Subsets: MEDLINE
Database: MEDLINE Ultimate
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PubType: Academic Journal
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  Data: Comparison of first-line cetuximab and panitumumab plus doublet chemotherapies for left-sided colorectal cancer: a multicenter real-world observational study by the Japanese Society for Cancer of the Colon and Rectum.
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  Data: <searchLink fieldCode="AU" term="%22Kawagoe+R%22">Kawagoe R</searchLink>; Department of Gastroenterology, Faculty of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, 305-8575, Japan.<br /><searchLink fieldCode="AU" term="%22Moriwaki+T%22">Moriwaki T</searchLink>; Department of Gastroenterology and Hepatology, Kurashiki Central Hospital, 1-1-1 Miwa, Kurashiki, 710-8602, Japan. tmoriwak@gmail.com.<br /><searchLink fieldCode="AU" term="%22Yamazaki+K%22">Yamazaki K</searchLink>; Division of Gastrointestinal Oncology, Shizuoka Cancer Center, 1007 Shimonagakubo, Suntou-gun, Nagaizumi-cho, Shizuoka, 411-8777, Japan.<br /><searchLink fieldCode="AU" term="%22Yukami+H%22">Yukami H</searchLink>; Department of Gastroenterology and Gastrointestinal Oncology, National Cancer Center Hospital East, 6-5-1 Kashiwanoha, Kashiwa, 277-8577, Japan.; Cancer Chemotherapy Center, Osaka Medical and Pharmaceutical University Hospital, 2-7 Daigaku-machi, Takatsuki, 569-8686, Japan.<br /><searchLink fieldCode="AU" term="%22Uetake+H%22">Uetake H</searchLink>; Department of Clinical Research, National Hospital Organization Disaster Medical Center, 3256 Midori-cho, Tachikawa, 190-0014, Japan.<br /><searchLink fieldCode="AU" term="%22Tsuda+M%22">Tsuda M</searchLink>; Department of Gastroenterological Oncology, Hyogo Cancer Center, 13-70 Kitaouji-cho, Akashi, 673-8558, Japan.<br /><searchLink fieldCode="AU" term="%22Suto+T%22">Suto T</searchLink>; Department of Gastroenterological Surgery, Yamagata Prefectural Central Hospital, 1800 Aoyagi, Yamagata, 990-2292, Japan.<br /><searchLink fieldCode="AU" term="%22Sugimoto+N%22">Sugimoto N</searchLink>; Department of Genetic Oncology, Osaka International Cancer Institute, 3-1-69 Otemae, Chuo-ku, Osaka, 541-8567, Japan.<br /><searchLink fieldCode="AU" term="%22Ojima+H%22">Ojima H</searchLink>; Department of Gastroenterological Surgery, Gunma Prefectural Cancer Center, 617-1 Takahayashi-nishi-cho, Ota, 373-8550, Japan.<br /><searchLink fieldCode="AU" term="%22Takii+Y%22">Takii Y</searchLink>; Department of Gastroenterological Surgery, Niigata Cancer Center Hospital, 2-15-3 Kawagishi-cho, Chuo-ku, Niigata, 951-8566, Japan.<br /><searchLink fieldCode="AU" term="%22Yasui+H%22">Yasui H</searchLink>; Department of Medical Oncology, Kobe City Medical Center General Hospital, 2-1-1 Minatojima-minami-machi, Chuo-ku, Kobe, 650-0047, Japan.<br /><searchLink fieldCode="AU" term="%22Komoda+M%22">Komoda M</searchLink>; Department of Gastrointestinal and Medical Oncology, National Hospital Organization Kyushu Cancer Center, 3-1-1 Notame, Minami-ku, Fukuoka, 811-1395, Japan.<br /><searchLink fieldCode="AU" term="%22Shimada+Y%22">Shimada Y</searchLink>; Division of Clinical Oncology, Kochi Health Sciences Center, 2125-1 Ike, Kochi, 781-8555, Japan.<br /><searchLink fieldCode="AU" term="%22Tsuji+A%22">Tsuji A</searchLink>; Department of Clinical Oncology, Kagawa University Faculty of Medicine, 1750-1 Ikenobe, Kita-gun, Miki-cho, Kagawa, 761-0793, Japan.<br /><searchLink fieldCode="AU" term="%22Yamaguchi+T%22">Yamaguchi T</searchLink>; Cancer Chemotherapy Center, Osaka Medical and Pharmaceutical University Hospital, 2-7 Daigaku-machi, Takatsuki, 569-8686, Japan.<br /><searchLink fieldCode="AU" term="%22Sawada+R%22">Sawada R</searchLink>; Division of Gastroenterology and Hepatology, Department of Internal Medicine, The Jikei University School of Medicine, 3-19-18 Nishi-shinbashi, Minato-ku, Tokyo, 105-8471, Japan.<br /><searchLink fieldCode="AU" term="%22Shinozaki+K%22">Shinozaki K</searchLink>; Division of Clinical Oncology, Hiroshima Prefectural Hospital, 1-5-54 Ujinakanda, Minami-ku, Hiroshima, 734-8530, Japan.<br /><searchLink fieldCode="AU" term="%22Otsu+S%22">Otsu S</searchLink>; Department of Medical Oncology and Hematology, Oita University Faculty of Medicine, 1-1 Idaigaoka, Hasama-machi, Yufu, 879-5593, Japan.<br /><searchLink fieldCode="AU" term="%22Shigeyasu+K%22">Shigeyasu K</searchLink>; Department of Gastroenterological Surgery, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, 2-5-1 Shikata-cho, Kita-ku, Okayama, 700-8558, Japan.<br /><searchLink fieldCode="AU" term="%22Tsuchihashi+K%22">Tsuchihashi K</searchLink>; Department of Hematology, Oncology and Cardiovascular Medicine, Kyushu University Hospital, 3-1-1 Maidashi, Higashi-ku, Fukuoka, 812-8582, Japan.<br /><searchLink fieldCode="AU" term="%22Tamura+T%22">Tamura T</searchLink>; Department of Medical Oncology, Kindai University Nara Hospital, 1248-1 Otoda-cho, Ikoma, 630-0293, Japan.<br /><searchLink fieldCode="AU" term="%22Shiozawa+M%22">Shiozawa M</searchLink>; Division of Gastrointestinal Surgery, Kanagawa Cancer Center, 2-3-2 Nakao, Asahi-ku, Yokohama, 241-8515, Japan.<br /><searchLink fieldCode="AU" term="%22Ueno+H%22">Ueno H</searchLink>; Department of Surgery, National Defense Medical College, 3-2 Namiki, Tokorozawa, 359-8513, Japan.<br /><searchLink fieldCode="AU" term="%22Denda+T%22">Denda T</searchLink>; Division of Gastroenterology, Chiba Cancer Center, 666-2 Nitona-cho, Chuo-ku, Chiba, 260-8717, Japan.<br /><searchLink fieldCode="AU" term="%22Ito+T%22">Ito T</searchLink>; Department of Gastroenterology, Japan Baptist Hospital, 47 Kitashirakawa-yamanomoto-cho, Sakyo-ku, Kyoto, 606-8273, Japan.<br /><searchLink fieldCode="AU" term="%22Takashima+A%22">Takashima A</searchLink>; Division of Gastrointestinal Medical Oncology, National Cancer Center Hospital, 5-1-1 Tsukiji, Chuo-ku, Tokyo, 104-0045, Japan.
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  Data: <searchLink fieldCode="JN" term="%229616295%22">International journal of clinical oncology</searchLink> [Int J Clin Oncol] 2026 May; Vol. 31 (5), pp. 851-858. <i>Date of Electronic Publication: </i>2026 Mar 04.
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