Quantification and transcriptome profiling reveal abundant, dynamic and translatable dephospho-CoA-capped RNAs.

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Title: Quantification and transcriptome profiling reveal abundant, dynamic and translatable dephospho-CoA-capped RNAs.
Authors: Hu H; Beijing Advanced Center of RNA Biology (BEACON), State Key Laboratory for Gene Function and Modulation Research, Peking-Tsinghua Joint Center for Life Sciences, School of Life Sciences, Peking University, Beijing, China. hao.hu@pku.edu.cn., Zhang Q; Beijing Advanced Center of RNA Biology (BEACON), State Key Laboratory for Gene Function and Modulation Research, Peking-Tsinghua Joint Center for Life Sciences, School of Life Sciences, Peking University, Beijing, China., Ma X; College of Life Sciences, Tianjin Key Laboratory of Animal and Plant Resistance, Tianjin Normal University, Tianjin, China., Chu HF; Department of Biological Sciences, Columbia University, New York, NY, USA., Wang H; Beijing Advanced Center of RNA Biology (BEACON), State Key Laboratory for Gene Function and Modulation Research, Peking-Tsinghua Joint Center for Life Sciences, School of Life Sciences, Peking University, Beijing, China., Guo Y; Beijing Advanced Center of RNA Biology (BEACON), State Key Laboratory for Gene Function and Modulation Research, Peking-Tsinghua Joint Center for Life Sciences, School of Life Sciences, Peking University, Beijing, China., Bai Y; Beijing Advanced Center of RNA Biology (BEACON), State Key Laboratory for Gene Function and Modulation Research, Peking-Tsinghua Joint Center for Life Sciences, School of Life Sciences, Peking University, Beijing, China., Wang Q; Beijing Advanced Center of RNA Biology (BEACON), State Key Laboratory for Gene Function and Modulation Research, Peking-Tsinghua Joint Center for Life Sciences, School of Life Sciences, Peking University, Beijing, China., Li Z; Interdisciplinary Science Center, State Key Laboratory of Integrated Management of Pest Insects and Rodents, Institute of Zoology, Chinese Academy of Sciences, Beijing, China., Zhao J; Beijing Advanced Center of RNA Biology (BEACON), State Key Laboratory for Gene Function and Modulation Research, Peking-Tsinghua Joint Center for Life Sciences, School of Life Sciences, Peking University, Beijing, China., Lin H; Beijing Advanced Center of RNA Biology (BEACON), State Key Laboratory for Gene Function and Modulation Research, Peking-Tsinghua Joint Center for Life Sciences, School of Life Sciences, Peking University, Beijing, China., You C; College of Life Sciences, Guangdong Provincial Key Laboratory for the Development Biology and Environmental Adaptation of Agricultural Organisms, South China Agricultural University, Guangzhou, Guangdong, China., Li X; Interdisciplinary Science Center, State Key Laboratory of Integrated Management of Pest Insects and Rodents, Institute of Zoology, Chinese Academy of Sciences, Beijing, China., Tong L; Department of Biological Sciences, Columbia University, New York, NY, USA., Chen X; Beijing Advanced Center of RNA Biology (BEACON), State Key Laboratory for Gene Function and Modulation Research, Peking-Tsinghua Joint Center for Life Sciences, School of Life Sciences, Peking University, Beijing, China. xuemei.chen@pku.edu.cn.
Source: Nature biotechnology [Nat Biotechnol] 2026 Mar 04. Date of Electronic Publication: 2026 Mar 04.
Publication Type: Journal Article
Journal Info: Publisher: Nature America Publishing Country of Publication: United States NLM ID: 9604648 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1546-1696 (Electronic) Linking ISSN: 10870156 NLM ISO Abbreviation: Nat Biotechnol Subsets: MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Hu+H%22">Hu H</searchLink>; Beijing Advanced Center of RNA Biology (BEACON), State Key Laboratory for Gene Function and Modulation Research, Peking-Tsinghua Joint Center for Life Sciences, School of Life Sciences, Peking University, Beijing, China. hao.hu@pku.edu.cn.<br /><searchLink fieldCode="AU" term="%22Zhang+Q%22">Zhang Q</searchLink>; Beijing Advanced Center of RNA Biology (BEACON), State Key Laboratory for Gene Function and Modulation Research, Peking-Tsinghua Joint Center for Life Sciences, School of Life Sciences, Peking University, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Ma+X%22">Ma X</searchLink>; College of Life Sciences, Tianjin Key Laboratory of Animal and Plant Resistance, Tianjin Normal University, Tianjin, China.<br /><searchLink fieldCode="AU" term="%22Chu+HF%22">Chu HF</searchLink>; Department of Biological Sciences, Columbia University, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Wang+H%22">Wang H</searchLink>; Beijing Advanced Center of RNA Biology (BEACON), State Key Laboratory for Gene Function and Modulation Research, Peking-Tsinghua Joint Center for Life Sciences, School of Life Sciences, Peking University, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Guo+Y%22">Guo Y</searchLink>; Beijing Advanced Center of RNA Biology (BEACON), State Key Laboratory for Gene Function and Modulation Research, Peking-Tsinghua Joint Center for Life Sciences, School of Life Sciences, Peking University, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Bai+Y%22">Bai Y</searchLink>; Beijing Advanced Center of RNA Biology (BEACON), State Key Laboratory for Gene Function and Modulation Research, Peking-Tsinghua Joint Center for Life Sciences, School of Life Sciences, Peking University, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Wang+Q%22">Wang Q</searchLink>; Beijing Advanced Center of RNA Biology (BEACON), State Key Laboratory for Gene Function and Modulation Research, Peking-Tsinghua Joint Center for Life Sciences, School of Life Sciences, Peking University, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Li+Z%22">Li Z</searchLink>; Interdisciplinary Science Center, State Key Laboratory of Integrated Management of Pest Insects and Rodents, Institute of Zoology, Chinese Academy of Sciences, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Zhao+J%22">Zhao J</searchLink>; Beijing Advanced Center of RNA Biology (BEACON), State Key Laboratory for Gene Function and Modulation Research, Peking-Tsinghua Joint Center for Life Sciences, School of Life Sciences, Peking University, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Lin+H%22">Lin H</searchLink>; Beijing Advanced Center of RNA Biology (BEACON), State Key Laboratory for Gene Function and Modulation Research, Peking-Tsinghua Joint Center for Life Sciences, School of Life Sciences, Peking University, Beijing, China.<br /><searchLink fieldCode="AU" term="%22You+C%22">You C</searchLink>; College of Life Sciences, Guangdong Provincial Key Laboratory for the Development Biology and Environmental Adaptation of Agricultural Organisms, South China Agricultural University, Guangzhou, Guangdong, China.<br /><searchLink fieldCode="AU" term="%22Li+X%22">Li X</searchLink>; Interdisciplinary Science Center, State Key Laboratory of Integrated Management of Pest Insects and Rodents, Institute of Zoology, Chinese Academy of Sciences, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Tong+L%22">Tong L</searchLink>; Department of Biological Sciences, Columbia University, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Chen+X%22">Chen X</searchLink>; Beijing Advanced Center of RNA Biology (BEACON), State Key Laboratory for Gene Function and Modulation Research, Peking-Tsinghua Joint Center for Life Sciences, School of Life Sciences, Peking University, Beijing, China. xuemei.chen@pku.edu.cn.
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