Luteolin-Loaded Chitosan Nanoparticles Attenuate Fenvalerate-Induced Nephrotoxicity and Humoral Immune Suppression via NRF2/HO-1 Activation and NF-κB-Mediated Inflammatory and Apoptotic Pathway Inhibition.
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| Title: | Luteolin-Loaded Chitosan Nanoparticles Attenuate Fenvalerate-Induced Nephrotoxicity and Humoral Immune Suppression via NRF2/HO-1 Activation and NF-κB-Mediated Inflammatory and Apoptotic Pathway Inhibition. |
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| Authors: | Hegazy AMS; Department of Anatomy, Faculty of Medicine, Northern Border University, Arar, Saudi Arabia., Al-Ghafari AB; Department of Biochemistry, Faculty of Science, King Abdulaziz University, Jeddah, Saudi Arabia.; Experimental Biochemistry Unit, King Fahd Medical Research Center, King Abdulaziz University, Jeddah, Saudi Arabia.; Editome: Precision Gene Editing Unit, King Fahd Medical Research Center, King Abdulaziz University, Jeddah, Saudi Arabia., Al Doghaither HA; Department of Biochemistry, Faculty of Science, King Abdulaziz University, Jeddah, Saudi Arabia., Elmorsy EM; Center for Health Research, Northern Border University, Arar, Saudi Arabia., M Aboraya D; Basic Sciences Department, Faculty of Physical Therapy, Horus University-Egypt, New Damietta, Egypt., Atta MMF; Department of Biochemistry, Faculty of veterinary medicine, Egyptian Chinese University, Cairo, Egypt., Sobh ZK; Department of Forensic Medicine and Clinical Toxicology, Faculty of Medicine, Alexandria University, Alexandria, Egypt., Sharif AF; Department of Forensic Medicine and Clinical Toxicology, Faculty of Medicine, Tanta University, Tanta, Egypt.; Department of Clinical Medical Sciences, College of Medicine, Dar Al-Uloom University, Riyadh, Saudi Arabia. |
| Source: | Journal of applied toxicology : JAT [J Appl Toxicol] 2026 Mar 05. Date of Electronic Publication: 2026 Mar 05. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: John Wiley And Sons Country of Publication: England NLM ID: 8109495 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1099-1263 (Electronic) Linking ISSN: 0260437X NLM ISO Abbreviation: J Appl Toxicol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 41784154 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Luteolin-Loaded Chitosan Nanoparticles Attenuate Fenvalerate-Induced Nephrotoxicity and Humoral Immune Suppression via NRF2/HO-1 Activation and NF-κB-Mediated Inflammatory and Apoptotic Pathway Inhibition. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Hegazy+AMS%22">Hegazy AMS</searchLink>; Department of Anatomy, Faculty of Medicine, Northern Border University, Arar, Saudi Arabia.<br /><searchLink fieldCode="AU" term="%22Al-Ghafari+AB%22">Al-Ghafari AB</searchLink>; Department of Biochemistry, Faculty of Science, King Abdulaziz University, Jeddah, Saudi Arabia.; Experimental Biochemistry Unit, King Fahd Medical Research Center, King Abdulaziz University, Jeddah, Saudi Arabia.; Editome: Precision Gene Editing Unit, King Fahd Medical Research Center, King Abdulaziz University, Jeddah, Saudi Arabia.<br /><searchLink fieldCode="AU" term="%22Al+Doghaither+HA%22">Al Doghaither HA</searchLink>; Department of Biochemistry, Faculty of Science, King Abdulaziz University, Jeddah, Saudi Arabia.<br /><searchLink fieldCode="AU" term="%22Elmorsy+EM%22">Elmorsy EM</searchLink>; Center for Health Research, Northern Border University, Arar, Saudi Arabia.<br /><searchLink fieldCode="AU" term="%22M+Aboraya+D%22">M Aboraya D</searchLink>; Basic Sciences Department, Faculty of Physical Therapy, Horus University-Egypt, New Damietta, Egypt.<br /><searchLink fieldCode="AU" term="%22Atta+MMF%22">Atta MMF</searchLink>; Department of Biochemistry, Faculty of veterinary medicine, Egyptian Chinese University, Cairo, Egypt.<br /><searchLink fieldCode="AU" term="%22Sobh+ZK%22">Sobh ZK</searchLink>; Department of Forensic Medicine and Clinical Toxicology, Faculty of Medicine, Alexandria University, Alexandria, Egypt.<br /><searchLink fieldCode="AU" term="%22Sharif+AF%22">Sharif AF</searchLink>; Department of Forensic Medicine and Clinical Toxicology, Faculty of Medicine, Tanta University, Tanta, Egypt.; Department of Clinical Medical Sciences, College of Medicine, Dar Al-Uloom University, Riyadh, Saudi Arabia. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%228109495%22">Journal of applied toxicology : JAT</searchLink> [J Appl Toxicol] 2026 Mar 05. <i>Date of Electronic Publication: </i>2026 Mar 05. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22John+Wiley+And+Sons%22">John Wiley And Sons </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>8109495 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1099-1263 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%220260437X%22">0260437X </searchLink><i>NLM ISO Abbreviation: </i>J Appl Toxicol <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=41784154 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1002/jat.70141 Languages: – Code: eng Text: English Titles: – TitleFull: Luteolin-Loaded Chitosan Nanoparticles Attenuate Fenvalerate-Induced Nephrotoxicity and Humoral Immune Suppression via NRF2/HO-1 Activation and NF-κB-Mediated Inflammatory and Apoptotic Pathway Inhibition. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Hegazy AMS – PersonEntity: Name: NameFull: Al-Ghafari AB – PersonEntity: Name: NameFull: Al Doghaither HA – PersonEntity: Name: NameFull: Elmorsy EM – PersonEntity: Name: NameFull: M Aboraya D – PersonEntity: Name: NameFull: Atta MMF – PersonEntity: Name: NameFull: Sobh ZK – PersonEntity: Name: NameFull: Sharif AF IsPartOfRelationships: – BibEntity: Dates: – D: 05 M: 03 Text: 2026 Mar 05 Type: published Y: 2026 Identifiers: – Type: issn-electronic Value: 1099-1263 Titles: – TitleFull: Journal of applied toxicology : JAT Type: main |
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