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Anti-spike IgG Avidity Enhances Neutralization of Severe Acute Respiratory Syndrome Coronavirus 2: A Prospective Study of Primary Infections and Immunizations.

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Title: Anti-spike IgG Avidity Enhances Neutralization of Severe Acute Respiratory Syndrome Coronavirus 2: A Prospective Study of Primary Infections and Immunizations.
Authors: Nurmi V; Department of Virology, Faculty of Medicine, University of Helsinki, Helsinki, Finland., Hedman L; Department of Virology, Faculty of Medicine, University of Helsinki, Helsinki, Finland., Vapalahti K; Department of Veterinary Biosciences, Faculty of Veterinary Medicine, University of Helsinki, Helsinki, Finland.; Department of Medical and Clinical Genetics, Faculty of Medicine, University of Helsinki, Helsinki, Finland., Hepojoki J; Department of Virology, Faculty of Medicine, University of Helsinki, Helsinki, Finland.; Institute of Veterinary Pathology, Vetsuisse Faculty, University of Zürich, Zürich, Switzerland., Uğurlu H; Department of Virology, Faculty of Medicine, University of Helsinki, Helsinki, Finland.; Department of Molecular Biology and Genetics, Faculty of Sciences, Erzurum Technical University, Erzurum, Turkey., Iheozor-Ejiofor R; Department of Virology, Faculty of Medicine, University of Helsinki, Helsinki, Finland., Knight C; Nuffield Department of Medicine, Peter Medawar Building for Pathogen Research, University of Oxford, Oxford, United Kingdom., Saksela K; Department of Virology, Faculty of Medicine, University of Helsinki, Helsinki, Finland.; HUS Diagnostic Center, Clinical Microbiology, Helsinki University Hospital and University of Helsinki, Helsinki, Finland., Kantele A; Department of Infectious Diseases, Inflammation Centre, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.; Human Microbiome Research Unit, University of Helsinki, Helsinki, Finland.; Meilahti Vaccine Research Center MeVac, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.; FIMAR, Finnish Multidisciplinary Center of Excellence in Antimicrobial Resistance Research, University of Helsinki, Helsinki, Finland., Hedman K; Department of Virology, Faculty of Medicine, University of Helsinki, Helsinki, Finland.; HUS Diagnostic Center, Clinical Microbiology, Helsinki University Hospital and University of Helsinki, Helsinki, Finland., Vapalahti O; Department of Virology, Faculty of Medicine, University of Helsinki, Helsinki, Finland.; Department of Veterinary Biosciences, Faculty of Veterinary Medicine, University of Helsinki, Helsinki, Finland.; HUS Diagnostic Center, Clinical Microbiology, Helsinki University Hospital and University of Helsinki, Helsinki, Finland.
Source: The Journal of infectious diseases [J Infect Dis] 2026 Jun 16; Vol. 233 (6), pp. e1374-e1385.
Publication Type: Journal Article
Journal Info: Publisher: Oxford University Press Country of Publication: United States NLM ID: 0413675 Publication Model: Print Cited Medium: Internet ISSN: 1537-6613 (Electronic) Linking ISSN: 00221899 NLM ISO Abbreviation: J Infect Dis Subsets: MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Nurmi+V%22">Nurmi V</searchLink>; Department of Virology, Faculty of Medicine, University of Helsinki, Helsinki, Finland.<br /><searchLink fieldCode="AU" term="%22Hedman+L%22">Hedman L</searchLink>; Department of Virology, Faculty of Medicine, University of Helsinki, Helsinki, Finland.<br /><searchLink fieldCode="AU" term="%22Vapalahti+K%22">Vapalahti K</searchLink>; Department of Veterinary Biosciences, Faculty of Veterinary Medicine, University of Helsinki, Helsinki, Finland.; Department of Medical and Clinical Genetics, Faculty of Medicine, University of Helsinki, Helsinki, Finland.<br /><searchLink fieldCode="AU" term="%22Hepojoki+J%22">Hepojoki J</searchLink>; Department of Virology, Faculty of Medicine, University of Helsinki, Helsinki, Finland.; Institute of Veterinary Pathology, Vetsuisse Faculty, University of Zürich, Zürich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Uğurlu+H%22">Uğurlu H</searchLink>; Department of Virology, Faculty of Medicine, University of Helsinki, Helsinki, Finland.; Department of Molecular Biology and Genetics, Faculty of Sciences, Erzurum Technical University, Erzurum, Turkey.<br /><searchLink fieldCode="AU" term="%22Iheozor-Ejiofor+R%22">Iheozor-Ejiofor R</searchLink>; Department of Virology, Faculty of Medicine, University of Helsinki, Helsinki, Finland.<br /><searchLink fieldCode="AU" term="%22Knight+C%22">Knight C</searchLink>; Nuffield Department of Medicine, Peter Medawar Building for Pathogen Research, University of Oxford, Oxford, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Saksela+K%22">Saksela K</searchLink>; Department of Virology, Faculty of Medicine, University of Helsinki, Helsinki, Finland.; HUS Diagnostic Center, Clinical Microbiology, Helsinki University Hospital and University of Helsinki, Helsinki, Finland.<br /><searchLink fieldCode="AU" term="%22Kantele+A%22">Kantele A</searchLink>; Department of Infectious Diseases, Inflammation Centre, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.; Human Microbiome Research Unit, University of Helsinki, Helsinki, Finland.; Meilahti Vaccine Research Center MeVac, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.; FIMAR, Finnish Multidisciplinary Center of Excellence in Antimicrobial Resistance Research, University of Helsinki, Helsinki, Finland.<br /><searchLink fieldCode="AU" term="%22Hedman+K%22">Hedman K</searchLink>; Department of Virology, Faculty of Medicine, University of Helsinki, Helsinki, Finland.; HUS Diagnostic Center, Clinical Microbiology, Helsinki University Hospital and University of Helsinki, Helsinki, Finland.<br /><searchLink fieldCode="AU" term="%22Vapalahti+O%22">Vapalahti O</searchLink>; Department of Virology, Faculty of Medicine, University of Helsinki, Helsinki, Finland.; Department of Veterinary Biosciences, Faculty of Veterinary Medicine, University of Helsinki, Helsinki, Finland.; HUS Diagnostic Center, Clinical Microbiology, Helsinki University Hospital and University of Helsinki, Helsinki, Finland.
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              Text: 2026 Jun 16
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