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Dietary copper-driven colonic dysbiosis mediates oxidative stress and butyrate deficiency to facilitate the spread of resistome in pigs.

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Title: Dietary copper-driven colonic dysbiosis mediates oxidative stress and butyrate deficiency to facilitate the spread of resistome in pigs.
Authors: Wen Y; State Key Laboratory for the Quality and Safety of Agro-Products, Zhejiang Provincial Key Laboratory of Agricultural Microbiomics, Institute of Agro-Product Safety and Nutrition, Zhejiang Academy of Agricultural Sciences, Hangzhou, China., Gao M; School of Life Sciences, Westlake University, Hangzhou, China., Wang Z; State Key Laboratory of Animal Nutrition, Frontiers Science Center for Molecular Design Breeding (MOE), China Agricultural University, Beijing, China., Liu X; State Key Laboratory of Animal Nutrition, Frontiers Science Center for Molecular Design Breeding (MOE), China Agricultural University, Beijing, China., Zhang Y; College of Environmental Science and Engineering, Tongji University, Shanghai, China., Lin G; Institute of Quality Standards and Testing Technology for Agricultural Products, Chinese Academy of Agricultural Sciences, Key Laboratory of Agrifood Safety and Quality, Ministry of Agriculture and Rural Affairs, Beijing, China., He P; State Key Laboratory of Animal Nutrition, Frontiers Science Center for Molecular Design Breeding (MOE), China Agricultural University, Beijing, China., Yang H; State Key Laboratory for the Quality and Safety of Agro-Products, Zhejiang Provincial Key Laboratory of Agricultural Microbiomics, Institute of Agro-Product Safety and Nutrition, Zhejiang Academy of Agricultural Sciences, Hangzhou, China. yanghua@zaas.ac.cn., Xiao Y; State Key Laboratory for the Quality and Safety of Agro-Products, Zhejiang Provincial Key Laboratory of Agricultural Microbiomics, Institute of Agro-Product Safety and Nutrition, Zhejiang Academy of Agricultural Sciences, Hangzhou, China. xiaoyp@zaas.ac.cn., Lyu W; State Key Laboratory for the Quality and Safety of Agro-Products, Zhejiang Provincial Key Laboratory of Agricultural Microbiomics, Institute of Agro-Product Safety and Nutrition, Zhejiang Academy of Agricultural Sciences, Hangzhou, China. lvwt@zaas.ac.cn.
Source: NPJ biofilms and microbiomes [NPJ Biofilms Microbiomes] 2026 Mar 05; Vol. 12 (1). Date of Electronic Publication: 2026 Mar 05.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: United States NLM ID: 101666944 Publication Model: Electronic Cited Medium: Internet ISSN: 2055-5008 (Electronic) Linking ISSN: 20555008 NLM ISO Abbreviation: NPJ Biofilms Microbiomes Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Dietary copper-driven colonic dysbiosis mediates oxidative stress and butyrate deficiency to facilitate the spread of resistome in pigs.
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  Data: <searchLink fieldCode="AU" term="%22Wen+Y%22">Wen Y</searchLink>; State Key Laboratory for the Quality and Safety of Agro-Products, Zhejiang Provincial Key Laboratory of Agricultural Microbiomics, Institute of Agro-Product Safety and Nutrition, Zhejiang Academy of Agricultural Sciences, Hangzhou, China.<br /><searchLink fieldCode="AU" term="%22Gao+M%22">Gao M</searchLink>; School of Life Sciences, Westlake University, Hangzhou, China.<br /><searchLink fieldCode="AU" term="%22Wang+Z%22">Wang Z</searchLink>; State Key Laboratory of Animal Nutrition, Frontiers Science Center for Molecular Design Breeding (MOE), China Agricultural University, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Liu+X%22">Liu X</searchLink>; State Key Laboratory of Animal Nutrition, Frontiers Science Center for Molecular Design Breeding (MOE), China Agricultural University, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Zhang+Y%22">Zhang Y</searchLink>; College of Environmental Science and Engineering, Tongji University, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Lin+G%22">Lin G</searchLink>; Institute of Quality Standards and Testing Technology for Agricultural Products, Chinese Academy of Agricultural Sciences, Key Laboratory of Agrifood Safety and Quality, Ministry of Agriculture and Rural Affairs, Beijing, China.<br /><searchLink fieldCode="AU" term="%22He+P%22">He P</searchLink>; State Key Laboratory of Animal Nutrition, Frontiers Science Center for Molecular Design Breeding (MOE), China Agricultural University, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Yang+H%22">Yang H</searchLink>; State Key Laboratory for the Quality and Safety of Agro-Products, Zhejiang Provincial Key Laboratory of Agricultural Microbiomics, Institute of Agro-Product Safety and Nutrition, Zhejiang Academy of Agricultural Sciences, Hangzhou, China. yanghua@zaas.ac.cn.<br /><searchLink fieldCode="AU" term="%22Xiao+Y%22">Xiao Y</searchLink>; State Key Laboratory for the Quality and Safety of Agro-Products, Zhejiang Provincial Key Laboratory of Agricultural Microbiomics, Institute of Agro-Product Safety and Nutrition, Zhejiang Academy of Agricultural Sciences, Hangzhou, China. xiaoyp@zaas.ac.cn.<br /><searchLink fieldCode="AU" term="%22Lyu+W%22">Lyu W</searchLink>; State Key Laboratory for the Quality and Safety of Agro-Products, Zhejiang Provincial Key Laboratory of Agricultural Microbiomics, Institute of Agro-Product Safety and Nutrition, Zhejiang Academy of Agricultural Sciences, Hangzhou, China. lvwt@zaas.ac.cn.
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  Data: <searchLink fieldCode="JN" term="%22101666944%22">NPJ biofilms and microbiomes</searchLink> [NPJ Biofilms Microbiomes] 2026 Mar 05; Vol. 12 (1). <i>Date of Electronic Publication: </i>2026 Mar 05.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Publishing+Group%22">Nature Publishing Group </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101666944 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2055-5008 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2220555008%22">20555008 </searchLink><i>NLM ISO Abbreviation: </i>NPJ Biofilms Microbiomes <i>Subsets: </i>MEDLINE
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        Value: 10.1038/s41522-026-00949-1
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            – D: 05
              M: 03
              Text: 2026 Mar 05
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