Clinical development of molecular residual disease (MRD) and multi-cancer early detection (MCED) using liquid biopsy multiomics with artificial intelligence (AI).
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| Title: | Clinical development of molecular residual disease (MRD) and multi-cancer early detection (MCED) using liquid biopsy multiomics with artificial intelligence (AI). |
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| Authors: | Shibuki T; Department of Hepatobiliary and Pancreatic Oncology, National Cancer Center Hospital East, Kashiwa, Japan. tshibuki@east.ncc.go.jp.; Department for the Promotion of Drug and Diagnostic Development, Division of Drug and Diagnostic Development Promotion, Translational Research Support Office, National Cancer Center Hospital East, 6-5-1, Kashiwanoha, Kashiwa, Chiba, 277-8577, Japan. tshibuki@east.ncc.go.jp., Yamashita R; Division of Translational Informatics, Exploratory Oncology Research and Clinical Trial Center, National Cancer Center Hospital East, Kashiwa, Japan., Hashimoto T; Department for the Promotion of Drug and Diagnostic Development, Division of Drug and Diagnostic Development Promotion, Translational Research Support Office, National Cancer Center Hospital East, 6-5-1, Kashiwanoha, Kashiwa, Chiba, 277-8577, Japan.; Department of Gastroenterology and Gastrointestinal Oncology, National Cancer Center Hospital East, Kashiwa, Japan., Fujisawa T; Department for the Promotion of Drug and Diagnostic Development, Division of Drug and Diagnostic Development Promotion, Translational Research Support Office, National Cancer Center Hospital East, 6-5-1, Kashiwanoha, Kashiwa, Chiba, 277-8577, Japan.; Department of Head and Neck Medical Oncology, National Cancer Center Hospital East, Kashiwa, Japan., Imai M; Department for the Promotion of Drug and Diagnostic Development, Division of Drug and Diagnostic Development Promotion, Translational Research Support Office, National Cancer Center Hospital East, 6-5-1, Kashiwanoha, Kashiwa, Chiba, 277-8577, Japan., Yuda J; Department of Hematology, National Cancer Center Hospital East, Kashiwa, Japan., Kuwata T; Department of Genetic Medicine and Services, National Cancer Center Hospital East, Kashiwa, Japan., Misumi T; Department of Data Science, National Cancer Center Hospital East, Chiba, Japan., Nakamura Y; Department for the Promotion of Drug and Diagnostic Development, Division of Drug and Diagnostic Development Promotion, Translational Research Support Office, National Cancer Center Hospital East, 6-5-1, Kashiwanoha, Kashiwa, Chiba, 277-8577, Japan.; Department of Gastroenterology and Gastrointestinal Oncology, National Cancer Center Hospital East, Kashiwa, Japan., Bando H; Department for the Promotion of Drug and Diagnostic Development, Division of Drug and Diagnostic Development Promotion, Translational Research Support Office, National Cancer Center Hospital East, 6-5-1, Kashiwanoha, Kashiwa, Chiba, 277-8577, Japan.; Department of Gastroenterology and Gastrointestinal Oncology, National Cancer Center Hospital East, Kashiwa, Japan., Kojima K; Tohoku Medical Megabank Organization, Tohoku University, Sendai, Japan., Tokioka S; Tohoku Medical Megabank Organization, Tohoku University, Sendai, Japan., Chiba I; Tohoku Medical Megabank Organization, Tohoku University, Sendai, Japan., Nakaya N; Tohoku Medical Megabank Organization, Tohoku University, Sendai, Japan., Hozawa A; Tohoku Medical Megabank Organization, Tohoku University, Sendai, Japan., Koshiba S; Tohoku Medical Megabank Organization, Tohoku University, Sendai, Japan., Fuse N; Tohoku Medical Megabank Organization, Tohoku University, Sendai, Japan., Saito S; Tohoku Medical Megabank Organization, Tohoku University, Sendai, Japan.; Advanced Research Center for Innovations in Next-Generation Medicine, Tohoku University, Sendai, Japan., Shimizu R; Tohoku Medical Megabank Organization, Tohoku University, Sendai, Japan., Park WY; GxD Inc., Kashiwa, Japan.; Translational Genomics Center, Samsung Medical Center, Seoul, Korea., Kinoshita K; Tohoku Medical Megabank Organization, Tohoku University, Sendai, Japan., Yoshino T; Department of Gastroenterology and Gastrointestinal Oncology, National Cancer Center Hospital East, Kashiwa, Japan. |
| Source: | International journal of clinical oncology [Int J Clin Oncol] 2026 May; Vol. 31 (5), pp. 843-850. Date of Electronic Publication: 2026 Mar 06. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Springer-Verlag Tokyo Country of Publication: Japan NLM ID: 9616295 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1437-7772 (Electronic) Linking ISSN: 13419625 NLM ISO Abbreviation: Int J Clin Oncol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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