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Impact of symptom duration on the effectiveness of intradiscal condoliase injection for lumbar disc herniation: A multicenter retrospective study.

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Title: Impact of symptom duration on the effectiveness of intradiscal condoliase injection for lumbar disc herniation: A multicenter retrospective study.
Authors: Watanabe K; Department of Orthopaedic Surgery, Keio University, Tokyo, Japan. Electronic address: kw197251@keio.jp., Takahashi Y; Department of Orthopaedic Surgery, Japanese Red Cross Shizuoka Hospital, Shizuoka, Japan., Michikawa T; Department of Environmental and Occupational Health, School of Medicine, Toho University, Tokyo, Japan., Takahashi T; Department of Orthopedics, Institute of Science Tokyo, Tokyo, Japan., Banno T; Department of Orthopaedic Surgery, Hamamatsu University School of Medicine, Hamamatsu, Japan., Sakaki K; Department of Orthopaedic Surgery, Saiseikai Kawaguchi General Hospital, Kawaguchi, Japan., Arai Y; Department of Orthopaedic Surgery, Saiseikai Kawaguchi General Hospital, Kawaguchi, Japan., Takano Y; Department of Orthopaedic Surgery, Inanami Spine and Joint Hospital, Tokyo, Japan., Eguchi Y; Department of Orthopaedic Surgery, JCHO Tokyo Joto Hospital, Tokyo, Japan; Department of Orthopaedic Surgery, Chiba University, Chiba, Japan., Taniguchi Y; Department of Orthopaedic Surgery, The University of Tokyo, Tokyo, Japan., Maki S; Department of Orthopaedic Surgery, Chiba University, Chiba, Japan., Aoki Y; Department of Orthopaedic Surgery, Eastern Chiba Medical Center, Togane, Japan., Fujii S; Department of Orthopaedic Surgery, Saiseikai Kawaguchi General Hospital, Kawaguchi, Japan., Sakaeda K; Department of Orthopedics, Institute of Science Tokyo, Tokyo, Japan., Matsukura Y; Department of Orthopedics, Institute of Science Tokyo, Tokyo, Japan., Akazawa T; Department of Orthopaedic Surgery, St. Marianna University School of Medicine, Kawasaki, Japan., Minamide A; Department of Orthopaedic Surgery, Kansai Medical University Medical Center, Osaka, Japan., Nojiri H; Department of Orthopaedic Surgery, Juntendo University, Tokyo, Japan., Sakai K; Department of Orthopaedic Surgery, Saiseikai Kawaguchi General Hospital, Kawaguchi, Japan., Kato S; Department of Orthopaedic Surgery, Kanazawa University, Kanazawa, Japan., Tamai K; Department of Orthopaedic Surgery, Osaka Metropolitan University Graduate School of Medicine, Osaka, Japan., Suzuki H; Department of Orthopaedic Surgery, Tokyo Medical University, Tokyo, Japan., Miyagi M; Department of Orthopaedic Surgery, Kitasato University School of Medicine, Sagamihara, Japan., Yoshii T; Department of Orthopedics, Institute of Science Tokyo, Tokyo, Japan., Yamada H; Department of Orthopaedic Surgery, Wakayama Medical University, Wakayama, Japan., Kaito T; Department of Orthopaedic Surgery, Osaka Rosai Hospital, Sakai, Japan., Hiraizumi Y; Department of Orthopaedic Surgery, Showa University School of Medicine, Tokyo, Japan., Yamagata M; Department of Orthopaedic Surgery, Oyuminochuobyoin Mobara Clinic, Mobara, Japan., Nakamura M; Department of Orthopaedic Surgery, Keio University, Tokyo, Japan., Hosogane N; Department of Orthopaedic Surgery, Kyorin University, Tokyo, Japan., Ohtori S; Department of Orthopaedic Surgery, Chiba University, Chiba, Japan., Hirai T; Department of Orthopedics, Institute of Science Tokyo, Tokyo, Japan.
Source: Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association [J Orthop Sci] 2026 Mar 05. Date of Electronic Publication: 2026 Mar 05.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Country of Publication: Japan NLM ID: 9604934 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1436-2023 (Electronic) Linking ISSN: 09492658 NLM ISO Abbreviation: J Orthop Sci Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Impact of symptom duration on the effectiveness of intradiscal condoliase injection for lumbar disc herniation: A multicenter retrospective study.
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  Data: <searchLink fieldCode="AU" term="%22Watanabe+K%22">Watanabe K</searchLink>; Department of Orthopaedic Surgery, Keio University, Tokyo, Japan. Electronic address: kw197251@keio.jp.<br /><searchLink fieldCode="AU" term="%22Takahashi+Y%22">Takahashi Y</searchLink>; Department of Orthopaedic Surgery, Japanese Red Cross Shizuoka Hospital, Shizuoka, Japan.<br /><searchLink fieldCode="AU" term="%22Michikawa+T%22">Michikawa T</searchLink>; Department of Environmental and Occupational Health, School of Medicine, Toho University, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Takahashi+T%22">Takahashi T</searchLink>; Department of Orthopedics, Institute of Science Tokyo, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Banno+T%22">Banno T</searchLink>; Department of Orthopaedic Surgery, Hamamatsu University School of Medicine, Hamamatsu, Japan.<br /><searchLink fieldCode="AU" term="%22Sakaki+K%22">Sakaki K</searchLink>; Department of Orthopaedic Surgery, Saiseikai Kawaguchi General Hospital, Kawaguchi, Japan.<br /><searchLink fieldCode="AU" term="%22Arai+Y%22">Arai Y</searchLink>; Department of Orthopaedic Surgery, Saiseikai Kawaguchi General Hospital, Kawaguchi, Japan.<br /><searchLink fieldCode="AU" term="%22Takano+Y%22">Takano Y</searchLink>; Department of Orthopaedic Surgery, Inanami Spine and Joint Hospital, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Eguchi+Y%22">Eguchi Y</searchLink>; Department of Orthopaedic Surgery, JCHO Tokyo Joto Hospital, Tokyo, Japan; Department of Orthopaedic Surgery, Chiba University, Chiba, Japan.<br /><searchLink fieldCode="AU" term="%22Taniguchi+Y%22">Taniguchi Y</searchLink>; Department of Orthopaedic Surgery, The University of Tokyo, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Maki+S%22">Maki S</searchLink>; Department of Orthopaedic Surgery, Chiba University, Chiba, Japan.<br /><searchLink fieldCode="AU" term="%22Aoki+Y%22">Aoki Y</searchLink>; Department of Orthopaedic Surgery, Eastern Chiba Medical Center, Togane, Japan.<br /><searchLink fieldCode="AU" term="%22Fujii+S%22">Fujii S</searchLink>; Department of Orthopaedic Surgery, Saiseikai Kawaguchi General Hospital, Kawaguchi, Japan.<br /><searchLink fieldCode="AU" term="%22Sakaeda+K%22">Sakaeda K</searchLink>; Department of Orthopedics, Institute of Science Tokyo, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Matsukura+Y%22">Matsukura Y</searchLink>; Department of Orthopedics, Institute of Science Tokyo, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Akazawa+T%22">Akazawa T</searchLink>; Department of Orthopaedic Surgery, St. Marianna University School of Medicine, Kawasaki, Japan.<br /><searchLink fieldCode="AU" term="%22Minamide+A%22">Minamide A</searchLink>; Department of Orthopaedic Surgery, Kansai Medical University Medical Center, Osaka, Japan.<br /><searchLink fieldCode="AU" term="%22Nojiri+H%22">Nojiri H</searchLink>; Department of Orthopaedic Surgery, Juntendo University, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Sakai+K%22">Sakai K</searchLink>; Department of Orthopaedic Surgery, Saiseikai Kawaguchi General Hospital, Kawaguchi, Japan.<br /><searchLink fieldCode="AU" term="%22Kato+S%22">Kato S</searchLink>; Department of Orthopaedic Surgery, Kanazawa University, Kanazawa, Japan.<br /><searchLink fieldCode="AU" term="%22Tamai+K%22">Tamai K</searchLink>; Department of Orthopaedic Surgery, Osaka Metropolitan University Graduate School of Medicine, Osaka, Japan.<br /><searchLink fieldCode="AU" term="%22Suzuki+H%22">Suzuki H</searchLink>; Department of Orthopaedic Surgery, Tokyo Medical University, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Miyagi+M%22">Miyagi M</searchLink>; Department of Orthopaedic Surgery, Kitasato University School of Medicine, Sagamihara, Japan.<br /><searchLink fieldCode="AU" term="%22Yoshii+T%22">Yoshii T</searchLink>; Department of Orthopedics, Institute of Science Tokyo, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Yamada+H%22">Yamada H</searchLink>; Department of Orthopaedic Surgery, Wakayama Medical University, Wakayama, Japan.<br /><searchLink fieldCode="AU" term="%22Kaito+T%22">Kaito T</searchLink>; Department of Orthopaedic Surgery, Osaka Rosai Hospital, Sakai, Japan.<br /><searchLink fieldCode="AU" term="%22Hiraizumi+Y%22">Hiraizumi Y</searchLink>; Department of Orthopaedic Surgery, Showa University School of Medicine, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Yamagata+M%22">Yamagata M</searchLink>; Department of Orthopaedic Surgery, Oyuminochuobyoin Mobara Clinic, Mobara, Japan.<br /><searchLink fieldCode="AU" term="%22Nakamura+M%22">Nakamura M</searchLink>; Department of Orthopaedic Surgery, Keio University, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Hosogane+N%22">Hosogane N</searchLink>; Department of Orthopaedic Surgery, Kyorin University, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Ohtori+S%22">Ohtori S</searchLink>; Department of Orthopaedic Surgery, Chiba University, Chiba, Japan.<br /><searchLink fieldCode="AU" term="%22Hirai+T%22">Hirai T</searchLink>; Department of Orthopedics, Institute of Science Tokyo, Tokyo, Japan.
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  Data: <searchLink fieldCode="JN" term="%229604934%22">Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association</searchLink> [J Orthop Sci] 2026 Mar 05. <i>Date of Electronic Publication: </i>2026 Mar 05.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier%22">Elsevier </searchLink><i>Country of Publication: </i>Japan <i>NLM ID: </i>9604934 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1436-2023 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2209492658%22">09492658 </searchLink><i>NLM ISO Abbreviation: </i>J Orthop Sci <i>Subsets: </i>MEDLINE
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