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REAL208, a Liposome-based Formulation of Phosphodiesterase Inhibitor, Protects Acute Kidney Deficiency in Mice.

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Title: REAL208, a Liposome-based Formulation of Phosphodiesterase Inhibitor, Protects Acute Kidney Deficiency in Mice.
Authors: Tsai JC; Department of Pharmacy, Realinn Life Science Limited, Taoyuan, 337, Taiwan.; Taipei Heart Institute, Taipei Medical University, Taipei, 110, Taiwan.; Division of Cardiology and Cardiovascular Research Center, Taipei Medical University Hospital, Taipei, 110, Taiwan., Lin YW; Institute of Oral Biology, National Yang Ming Chiao Tung University (Taipei Campus), Taipei, 112, Taiwan., Huang CY; Taipei Heart Institute, Taipei Medical University, Taipei, 110, Taiwan.; Division of Cardiology and Cardiovascular Research Center, Taipei Medical University Hospital, Taipei, 110, Taiwan.; Division of Cardiology, Department of Internal Medicine, School of Medicine, College of Medicine, Taipei Medical University, Taipei, 110, Taiwan., Shih CM; Taipei Heart Institute, Taipei Medical University, Taipei, 110, Taiwan.; Division of Cardiology and Cardiovascular Research Center, Taipei Medical University Hospital, Taipei, 110, Taiwan.; Division of Cardiology, Department of Internal Medicine, School of Medicine, College of Medicine, Taipei Medical University, Taipei, 110, Taiwan., Wu YT; School of Pharmacy, College of Pharmacy, Kaohsiung Medical University, Kaohsiung, 807, Taiwan., Kurosaki T; Lipid Division, Nippon Fine Chemical CO., LTD., , Takasago, Hyogo, 676, Japan., Inoue Y; Lipid Division, Nippon Fine Chemical CO., LTD., , Takasago, Hyogo, 676, Japan., Du YC; Department of Pharmacy, Realinn Life Science Limited, Taoyuan, 337, Taiwan., Lin FY; Taipei Heart Institute, Taipei Medical University, Taipei, 110, Taiwan. g870905@tmu.edu.tw.; Division of Cardiology and Cardiovascular Research Center, Taipei Medical University Hospital, Taipei, 110, Taiwan. g870905@tmu.edu.tw.; Division of Cardiology, Department of Internal Medicine, School of Medicine, College of Medicine, Taipei Medical University, Taipei, 110, Taiwan. g870905@tmu.edu.tw.
Source: Pharmaceutical research [Pharm Res] 2026 Apr; Vol. 43 (4), pp. 1157-1175. Date of Electronic Publication: 2026 Mar 06.
Publication Type: Journal Article
Journal Info: Publisher: Kluwer Academic/Plenum Publishers Country of Publication: United States NLM ID: 8406521 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1573-904X (Electronic) Linking ISSN: 07248741 NLM ISO Abbreviation: Pharm Res Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: REAL208, a Liposome-based Formulation of Phosphodiesterase Inhibitor, Protects Acute Kidney Deficiency in Mice.
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  Data: <searchLink fieldCode="AU" term="%22Tsai+JC%22">Tsai JC</searchLink>; Department of Pharmacy, Realinn Life Science Limited, Taoyuan, 337, Taiwan.; Taipei Heart Institute, Taipei Medical University, Taipei, 110, Taiwan.; Division of Cardiology and Cardiovascular Research Center, Taipei Medical University Hospital, Taipei, 110, Taiwan.<br /><searchLink fieldCode="AU" term="%22Lin+YW%22">Lin YW</searchLink>; Institute of Oral Biology, National Yang Ming Chiao Tung University (Taipei Campus), Taipei, 112, Taiwan.<br /><searchLink fieldCode="AU" term="%22Huang+CY%22">Huang CY</searchLink>; Taipei Heart Institute, Taipei Medical University, Taipei, 110, Taiwan.; Division of Cardiology and Cardiovascular Research Center, Taipei Medical University Hospital, Taipei, 110, Taiwan.; Division of Cardiology, Department of Internal Medicine, School of Medicine, College of Medicine, Taipei Medical University, Taipei, 110, Taiwan.<br /><searchLink fieldCode="AU" term="%22Shih+CM%22">Shih CM</searchLink>; Taipei Heart Institute, Taipei Medical University, Taipei, 110, Taiwan.; Division of Cardiology and Cardiovascular Research Center, Taipei Medical University Hospital, Taipei, 110, Taiwan.; Division of Cardiology, Department of Internal Medicine, School of Medicine, College of Medicine, Taipei Medical University, Taipei, 110, Taiwan.<br /><searchLink fieldCode="AU" term="%22Wu+YT%22">Wu YT</searchLink>; School of Pharmacy, College of Pharmacy, Kaohsiung Medical University, Kaohsiung, 807, Taiwan.<br /><searchLink fieldCode="AU" term="%22Kurosaki+T%22">Kurosaki T</searchLink>; Lipid Division, Nippon Fine Chemical CO., LTD., , Takasago, Hyogo, 676, Japan.<br /><searchLink fieldCode="AU" term="%22Inoue+Y%22">Inoue Y</searchLink>; Lipid Division, Nippon Fine Chemical CO., LTD., , Takasago, Hyogo, 676, Japan.<br /><searchLink fieldCode="AU" term="%22Du+YC%22">Du YC</searchLink>; Department of Pharmacy, Realinn Life Science Limited, Taoyuan, 337, Taiwan.<br /><searchLink fieldCode="AU" term="%22Lin+FY%22">Lin FY</searchLink>; Taipei Heart Institute, Taipei Medical University, Taipei, 110, Taiwan. g870905@tmu.edu.tw.; Division of Cardiology and Cardiovascular Research Center, Taipei Medical University Hospital, Taipei, 110, Taiwan. g870905@tmu.edu.tw.; Division of Cardiology, Department of Internal Medicine, School of Medicine, College of Medicine, Taipei Medical University, Taipei, 110, Taiwan. g870905@tmu.edu.tw.
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  Data: <searchLink fieldCode="JN" term="%228406521%22">Pharmaceutical research</searchLink> [Pharm Res] 2026 Apr; Vol. 43 (4), pp. 1157-1175. <i>Date of Electronic Publication: </i>2026 Mar 06.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Kluwer+Academic%2FPlenum+Publishers%22">Kluwer Academic/Plenum Publishers </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>8406521 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1573-904X (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2207248741%22">07248741 </searchLink><i>NLM ISO Abbreviation: </i>Pharm Res <i>Subsets: </i>MEDLINE
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RecordInfo BibRecord:
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      – Type: doi
        Value: 10.1007/s11095-026-04065-9
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      – Code: eng
        Text: English
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              M: 04
              Text: 2026 Apr
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              Y: 2026
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