View in EDS

Elucidating the pharmacological mechanism of Yangming-Kaixin-Yizhi formula in inhibiting neuronal ferroptosis via Nrf2 in Alzheimer's disease: a study combining network pharmacology, transcriptomics, and experimental validation.

Saved in:
Bibliographic Details
Title: Elucidating the pharmacological mechanism of Yangming-Kaixin-Yizhi formula in inhibiting neuronal ferroptosis via Nrf2 in Alzheimer's disease: a study combining network pharmacology, transcriptomics, and experimental validation.
Authors: Xiong R; Department of Pharmacy, Jiangbei Campus of The First Affiliated Hospital of Army Medical University (The 958th Hospital of Chinese People's Liberation Army), Chongqing, China., Liu P; Research Institute of Acupuncture and Meridian, Anhui University of Chinese Medicine, Hefei, China., Wang L; Department of Pharmacy, Jiangbei Campus of The First Affiliated Hospital of Army Medical University (The 958th Hospital of Chinese People's Liberation Army), Chongqing, China., Zhang S; Department of Pharmacy, Jiangbei Campus of The First Affiliated Hospital of Army Medical University (The 958th Hospital of Chinese People's Liberation Army), Chongqing, China., Liu H; Department of Pharmacy, Jiangbei Campus of The First Affiliated Hospital of Army Medical University (The 958th Hospital of Chinese People's Liberation Army), Chongqing, China., Rong C; Key Laboratory of Chinese Medicine Clinical Research, Education Department of Guangxi Zhuang Autonomous Region, The First Affiliated Hospital of Guangxi University of Chinese Medicine, Guangxi Health Commission Guangxi Key Laboratory of Molecular Biology of Preventive Medicine of Traditional Chinese Medicine, Nanning, China., Kehriman N; Department of Pharmacy, Jiangbei Campus of The First Affiliated Hospital of Army Medical University (The 958th Hospital of Chinese People's Liberation Army), Chongqing, China., Wang J; Department of Pharmacy, Jiangbei Campus of The First Affiliated Hospital of Army Medical University (The 958th Hospital of Chinese People's Liberation Army), Chongqing, China., Wang J; Research Institute of Acupuncture and Meridian, Anhui University of Chinese Medicine, Hefei, China. wangjing2161@ahtcm.edu.cn., Lai X; Department of Pharmacy, Jiangbei Campus of The First Affiliated Hospital of Army Medical University (The 958th Hospital of Chinese People's Liberation Army), Chongqing, China. lxd0926@tmmu.edu.cn., Tang Y; Laboratory Animal Centre, Model Animal and Human Disease Research of Luzhou Key Laboratory, Southwest Medical University, Luzhou, China. tangy1989@swmu.edu.cn.; College of Integeration of Traditional Chinese and Western Medicine, The Affiliated Traditional Chinese Medicine Hospital, Southwest Medical University, Luzhou, China. tangy1989@swmu.edu.cn.
Source: Metabolic brain disease [Metab Brain Dis] 2026 Mar 07; Vol. 41 (1). Date of Electronic Publication: 2026 Mar 07.
Publication Type: Journal Article
Journal Info: Publisher: Springer Country of Publication: United States NLM ID: 8610370 Publication Model: Electronic Cited Medium: Internet ISSN: 1573-7365 (Electronic) Linking ISSN: 08857490 NLM ISO Abbreviation: Metab Brain Dis Subsets: MEDLINE
Database: MEDLINE Ultimate
FullText Text:
  Availability: 0
Header DbId: mdl
DbLabel: MEDLINE Ultimate
An: 41793523
AccessLevel: 2
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Elucidating the pharmacological mechanism of Yangming-Kaixin-Yizhi formula in inhibiting neuronal ferroptosis via Nrf2 in Alzheimer's disease: a study combining network pharmacology, transcriptomics, and experimental validation.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AU" term="%22Xiong+R%22">Xiong R</searchLink>; Department of Pharmacy, Jiangbei Campus of The First Affiliated Hospital of Army Medical University (The 958th Hospital of Chinese People's Liberation Army), Chongqing, China.<br /><searchLink fieldCode="AU" term="%22Liu+P%22">Liu P</searchLink>; Research Institute of Acupuncture and Meridian, Anhui University of Chinese Medicine, Hefei, China.<br /><searchLink fieldCode="AU" term="%22Wang+L%22">Wang L</searchLink>; Department of Pharmacy, Jiangbei Campus of The First Affiliated Hospital of Army Medical University (The 958th Hospital of Chinese People's Liberation Army), Chongqing, China.<br /><searchLink fieldCode="AU" term="%22Zhang+S%22">Zhang S</searchLink>; Department of Pharmacy, Jiangbei Campus of The First Affiliated Hospital of Army Medical University (The 958th Hospital of Chinese People's Liberation Army), Chongqing, China.<br /><searchLink fieldCode="AU" term="%22Liu+H%22">Liu H</searchLink>; Department of Pharmacy, Jiangbei Campus of The First Affiliated Hospital of Army Medical University (The 958th Hospital of Chinese People's Liberation Army), Chongqing, China.<br /><searchLink fieldCode="AU" term="%22Rong+C%22">Rong C</searchLink>; Key Laboratory of Chinese Medicine Clinical Research, Education Department of Guangxi Zhuang Autonomous Region, The First Affiliated Hospital of Guangxi University of Chinese Medicine, Guangxi Health Commission Guangxi Key Laboratory of Molecular Biology of Preventive Medicine of Traditional Chinese Medicine, Nanning, China.<br /><searchLink fieldCode="AU" term="%22Kehriman+N%22">Kehriman N</searchLink>; Department of Pharmacy, Jiangbei Campus of The First Affiliated Hospital of Army Medical University (The 958th Hospital of Chinese People's Liberation Army), Chongqing, China.<br /><searchLink fieldCode="AU" term="%22Wang+J%22">Wang J</searchLink>; Department of Pharmacy, Jiangbei Campus of The First Affiliated Hospital of Army Medical University (The 958th Hospital of Chinese People's Liberation Army), Chongqing, China.<br /><searchLink fieldCode="AU" term="%22Wang+J%22">Wang J</searchLink>; Research Institute of Acupuncture and Meridian, Anhui University of Chinese Medicine, Hefei, China. wangjing2161@ahtcm.edu.cn.<br /><searchLink fieldCode="AU" term="%22Lai+X%22">Lai X</searchLink>; Department of Pharmacy, Jiangbei Campus of The First Affiliated Hospital of Army Medical University (The 958th Hospital of Chinese People's Liberation Army), Chongqing, China. lxd0926@tmmu.edu.cn.<br /><searchLink fieldCode="AU" term="%22Tang+Y%22">Tang Y</searchLink>; Laboratory Animal Centre, Model Animal and Human Disease Research of Luzhou Key Laboratory, Southwest Medical University, Luzhou, China. tangy1989@swmu.edu.cn.; College of Integeration of Traditional Chinese and Western Medicine, The Affiliated Traditional Chinese Medicine Hospital, Southwest Medical University, Luzhou, China. tangy1989@swmu.edu.cn.
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%228610370%22">Metabolic brain disease</searchLink> [Metab Brain Dis] 2026 Mar 07; Vol. 41 (1). <i>Date of Electronic Publication: </i>2026 Mar 07.
– Name: TypePub
  Label: Publication Type
  Group: TypPub
  Data: Journal Article
– Name: TitleSource
  Label: Journal Info
  Group: Src
  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Springer%22">Springer </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>8610370 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1573-7365 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2208857490%22">08857490 </searchLink><i>NLM ISO Abbreviation: </i>Metab Brain Dis <i>Subsets: </i>MEDLINE
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=41793523
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1007/s11011-026-01814-y
    Languages:
      – Code: eng
        Text: English
    Titles:
      – TitleFull: Elucidating the pharmacological mechanism of Yangming-Kaixin-Yizhi formula in inhibiting neuronal ferroptosis via Nrf2 in Alzheimer's disease: a study combining network pharmacology, transcriptomics, and experimental validation.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Xiong R
      – PersonEntity:
          Name:
            NameFull: Liu P
      – PersonEntity:
          Name:
            NameFull: Wang L
      – PersonEntity:
          Name:
            NameFull: Zhang S
      – PersonEntity:
          Name:
            NameFull: Liu H
      – PersonEntity:
          Name:
            NameFull: Rong C
      – PersonEntity:
          Name:
            NameFull: Kehriman N
      – PersonEntity:
          Name:
            NameFull: Wang J
      – PersonEntity:
          Name:
            NameFull: Wang J
      – PersonEntity:
          Name:
            NameFull: Lai X
      – PersonEntity:
          Name:
            NameFull: Tang Y
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 07
              M: 03
              Text: 2026 Mar 07
              Type: published
              Y: 2026
          Identifiers:
            – Type: issn-electronic
              Value: 1573-7365
          Numbering:
            – Type: volume
              Value: 41
            – Type: issue
              Value: 1
          Titles:
            – TitleFull: Metabolic brain disease
              Type: main
ResultId 1