Endothelial ADGRF5(GPR116) governs vascular adaptation required for sustained thermogenic remodeling of brown adipose tissue.
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| Title: | Endothelial ADGRF5(GPR116) governs vascular adaptation required for sustained thermogenic remodeling of brown adipose tissue. |
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| Authors: | El-Merahbi R; Institute for Diabetes and Cancer (IDC), Helmholtz Diabetes Center Munich, Neuherberg, Germany; Helmholtz Center Munich, German Research Center for Environmental Health, Computational Health Center, Munich, Germany; German Center for Diabetes Research (DZD), Neuherberg, Germany; Joint Heidelberg-IDC Translational Diabetes Program, Inner Medicine 1, Heidelberg University Hospital, Heidelberg, Germany; Molecular Metabolic Control, Medical Faculty, Technical University of Munich, Germany., Karagiannakou V; Institute for Diabetes and Cancer (IDC), Helmholtz Diabetes Center Munich, Neuherberg, Germany; Helmholtz Center Munich, German Research Center for Environmental Health, Computational Health Center, Munich, Germany; German Center for Diabetes Research (DZD), Neuherberg, Germany; Joint Heidelberg-IDC Translational Diabetes Program, Inner Medicine 1, Heidelberg University Hospital, Heidelberg, Germany; Molecular Metabolic Control, Medical Faculty, Technical University of Munich, Germany., Kardinal R; Biophysical Imaging, Institute of Innate Immunity, Medical Faculty, University of Bonn, Bonn, Germany., Seep L; Life and Medical Sciences (LIMES) Institute and Bonn Center for Mathematical Life Sciences, University of Bonn, Bonn, Germany., Lindner R; Helmholtz Center Munich, German Research Center for Environmental Health, Computational Health Center, Munich, Germany; Helmholtz Center Munich, Core Facility Pathology and Tissue Analytics, Germany., Jäckstein MY; Department of Biochemistry and Molecular Cell Biology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Hildebrand S; Institute of Pharmacology and Toxicology, University Hospital, University of Bonn, Bonn, Germany., Hasic M; Chair of Molecular Nutritional Medicine, TUM School of Life Sciences, Technical University of Munich, Freising, Germany., Korkmaz E; Institute for Diabetes and Cancer (IDC), Helmholtz Diabetes Center Munich, Neuherberg, Germany; Helmholtz Center Munich, German Research Center for Environmental Health, Computational Health Center, Munich, Germany; German Center for Diabetes Research (DZD), Neuherberg, Germany; Joint Heidelberg-IDC Translational Diabetes Program, Inner Medicine 1, Heidelberg University Hospital, Heidelberg, Germany; Molecular Metabolic Control, Medical Faculty, Technical University of Munich, Germany., Jha AK; Institute for Diabetes and Cancer (IDC), Helmholtz Diabetes Center Munich, Neuherberg, Germany; Helmholtz Center Munich, German Research Center for Environmental Health, Computational Health Center, Munich, Germany; German Center for Diabetes Research (DZD), Neuherberg, Germany; Joint Heidelberg-IDC Translational Diabetes Program, Inner Medicine 1, Heidelberg University Hospital, Heidelberg, Germany; Molecular Metabolic Control, Medical Faculty, Technical University of Munich, Germany., Krokidi AT; Institute for Diabetes and Cancer (IDC), Helmholtz Diabetes Center Munich, Neuherberg, Germany; Helmholtz Center Munich, German Research Center for Environmental Health, Computational Health Center, Munich, Germany; German Center for Diabetes Research (DZD), Neuherberg, Germany; Joint Heidelberg-IDC Translational Diabetes Program, Inner Medicine 1, Heidelberg University Hospital, Heidelberg, Germany; Molecular Metabolic Control, Medical Faculty, Technical University of Munich, Germany., Dyar K; Institute for Diabetes and Cancer (IDC), Helmholtz Diabetes Center Munich, Neuherberg, Germany; Helmholtz Center Munich, German Research Center for Environmental Health, Computational Health Center, Munich, Germany; German Center for Diabetes Research (DZD), Neuherberg, Germany; Joint Heidelberg-IDC Translational Diabetes Program, Inner Medicine 1, Heidelberg University Hospital, Heidelberg, Germany; Molecular Metabolic Control, Medical Faculty, Technical University of Munich, Germany., Meissner F; Systems Immunology and Proteomics, Institute of Innate Immunity, Medical Faculty, University of Bonn, Bonn, Germany., Grein S; Life and Medical Sciences (LIMES) Institute and Bonn Center for Mathematical Life Sciences, University of Bonn, Bonn, Germany., Heeren J; Department of Biochemistry and Molecular Cell Biology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Klingenspor M; Chair of Molecular Nutritional Medicine, TUM School of Life Sciences, Technical University of Munich, Freising, Germany., Pfeifer A; Institute of Pharmacology and Toxicology, University Hospital, University of Bonn, Bonn, Germany., Hasenauer J; Life and Medical Sciences (LIMES) Institute and Bonn Center for Mathematical Life Sciences, University of Bonn, Bonn, Germany., Wachten D; Biophysical Imaging, Institute of Innate Immunity, Medical Faculty, University of Bonn, Bonn, Germany., Herzig S; Institute for Diabetes and Cancer (IDC), Helmholtz Diabetes Center Munich, Neuherberg, Germany; Helmholtz Center Munich, German Research Center for Environmental Health, Computational Health Center, Munich, Germany; German Center for Diabetes Research (DZD), Neuherberg, Germany; Joint Heidelberg-IDC Translational Diabetes Program, Inner Medicine 1, Heidelberg University Hospital, Heidelberg, Germany; Molecular Metabolic Control, Medical Faculty, Technical University of Munich, Germany., Georgiadi A; Institute for Diabetes and Cancer (IDC), Helmholtz Diabetes Center Munich, Neuherberg, Germany; Helmholtz Center Munich, German Research Center for Environmental Health, Computational Health Center, Munich, Germany; German Center for Diabetes Research (DZD), Neuherberg, Germany; Joint Heidelberg-IDC Translational Diabetes Program, Inner Medicine 1, Heidelberg University Hospital, Heidelberg, Germany; Molecular Metabolic Control, Medical Faculty, Technical University of Munich, Germany. Electronic address: anastasia.georgiadi@helmholtz-munich.de. |
| Source: | Molecular metabolism [Mol Metab] 2026 May; Vol. 107, pp. 102346. Date of Electronic Publication: 2026 Mar 06. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Elsevier GmbH Country of Publication: Germany NLM ID: 101605730 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2212-8778 (Electronic) Linking ISSN: 22128778 NLM ISO Abbreviation: Mol Metab Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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