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The STAT3-ZEB1 axis contributes to CCL2-mediated resistance to osimertinib in lung cancer.

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Title: The STAT3-ZEB1 axis contributes to CCL2-mediated resistance to osimertinib in lung cancer.
Authors: Chang TH; Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan., Tsai MF; Department of Biomedical Sciences, Da-Yeh University, Changhua, Taiwan., Wu SG; Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.; Department of Internal Medicine, National Taiwan University Cancer Center, Taipei, Taiwan., Liu YN; Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan., Wu HD; Department of Integrated Diagnostics & Therapeutics, National Taiwan University Hospital, Taipei, Taiwan., Tsai TH; Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan., Jheng HN; Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan., Hsu CL; Department of Medical Research, National Taiwan University Hospital, Taipei, Taiwan., Yeh PS; Department of Critical Care Medicine, Min-Sheng General Hospital, Taoyuan, Taiwan., Shih JY; Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.; Graduate Institute of Clinical Medicine, College of Medicine, National Taiwan University, Taipei, Taiwan.
Source: Frontiers in oncology [Front Oncol] 2026 Feb 20; Vol. 16, pp. 1699471. Date of Electronic Publication: 2026 Feb 20 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101568867 Publication Model: eCollection Cited Medium: Print ISSN: 2234-943X (Print) Linking ISSN: 2234943X NLM ISO Abbreviation: Front Oncol Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: The STAT3-ZEB1 axis contributes to CCL2-mediated resistance to osimertinib in lung cancer.
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  Data: <searchLink fieldCode="AU" term="%22Chang+TH%22">Chang TH</searchLink>; Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.<br /><searchLink fieldCode="AU" term="%22Tsai+MF%22">Tsai MF</searchLink>; Department of Biomedical Sciences, Da-Yeh University, Changhua, Taiwan.<br /><searchLink fieldCode="AU" term="%22Wu+SG%22">Wu SG</searchLink>; Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.; Department of Internal Medicine, National Taiwan University Cancer Center, Taipei, Taiwan.<br /><searchLink fieldCode="AU" term="%22Liu+YN%22">Liu YN</searchLink>; Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.<br /><searchLink fieldCode="AU" term="%22Wu+HD%22">Wu HD</searchLink>; Department of Integrated Diagnostics & Therapeutics, National Taiwan University Hospital, Taipei, Taiwan.<br /><searchLink fieldCode="AU" term="%22Tsai+TH%22">Tsai TH</searchLink>; Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.<br /><searchLink fieldCode="AU" term="%22Jheng+HN%22">Jheng HN</searchLink>; Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.<br /><searchLink fieldCode="AU" term="%22Hsu+CL%22">Hsu CL</searchLink>; Department of Medical Research, National Taiwan University Hospital, Taipei, Taiwan.<br /><searchLink fieldCode="AU" term="%22Yeh+PS%22">Yeh PS</searchLink>; Department of Critical Care Medicine, Min-Sheng General Hospital, Taoyuan, Taiwan.<br /><searchLink fieldCode="AU" term="%22Shih+JY%22">Shih JY</searchLink>; Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.; Graduate Institute of Clinical Medicine, College of Medicine, National Taiwan University, Taipei, Taiwan.
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  Data: <searchLink fieldCode="JN" term="%22101568867%22">Frontiers in oncology</searchLink> [Front Oncol] 2026 Feb 20; Vol. 16, pp. 1699471. <i>Date of Electronic Publication: </i>2026 Feb 20 (<i>Print Publication: </i>2026).
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Frontiers+Research+Foundation]%22">Frontiers Research Foundation] </searchLink><i>Country of Publication: </i>Switzerland <i>NLM ID: </i>101568867 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Print <i>ISSN: </i>2234-943X (Print) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%222234943X%22">2234943X </searchLink><i>NLM ISO Abbreviation: </i>Front Oncol <i>Subsets: </i>PubMed not MEDLINE
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              Text: 2026 Feb 20
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