Impact of proton pump inhibitors on immunotherapy is modulated by prior chemotherapy and linked to gut microbiome-immune cell signatures.
Saved in:
| Title: | Impact of proton pump inhibitors on immunotherapy is modulated by prior chemotherapy and linked to gut microbiome-immune cell signatures. |
|---|---|
| Authors: | Petouhoff A; The Ohio State University Comprehensive Cancer Center, Columbus, OH, USA., Hicks R; The Ohio State University Comprehensive Cancer Center, Columbus, OH, USA., Husain M; The Ohio State University Comprehensive Cancer Center, Columbus, OH, USA., Hoyd R; The Ohio State University Comprehensive Cancer Center, Columbus, OH, USA., Xu M; The Ohio State University Comprehensive Cancer Center, Columbus, OH, USA., Dravillas C; The Ohio State University Comprehensive Cancer Center, Columbus, OH, USA., Patel SH; The Ohio State University Comprehensive Cancer Center, Columbus, OH, USA., Johns A; The Ohio State University Comprehensive Cancer Center, Columbus, OH, USA., Grogan M; The Ohio State University Comprehensive Cancer Center, Columbus, OH, USA., Li M; The Ohio State University Comprehensive Cancer Center, Columbus, OH, USA.; Division of Medical Oncology, Department of Internal Medicine, 1800 Cannon Drive, Suite 1335, Columbus, OH, 43210, USA., Lopez G; The Ohio State University Comprehensive Cancer Center, Columbus, OH, USA., Miah A; The Ohio State University Comprehensive Cancer Center, Columbus, OH, USA., Liu Y; The Ohio State University Comprehensive Cancer Center, Columbus, OH, USA., Muniak M; The Ohio State University Comprehensive Cancer Center, Columbus, OH, USA., Schmidt M; The Ohio State University Comprehensive Cancer Center, Columbus, OH, USA., Das A; The Ohio State University Comprehensive Cancer Center, Columbus, OH, USA., Lathrop H; The Ohio State University Comprehensive Cancer Center, Columbus, OH, USA., Das P; The Ohio State University Comprehensive Cancer Center, Columbus, OH, USA., Secor A; The Ohio State University Comprehensive Cancer Center, Columbus, OH, USA., Haddad T; The Ohio State University Comprehensive Cancer Center, Columbus, OH, USA., Tinoco G; The Ohio State University Comprehensive Cancer Center, Columbus, OH, USA.; Division of Medical Oncology, Department of Internal Medicine, 1800 Cannon Drive, Suite 1335, Columbus, OH, 43210, USA., Carbone D; The Ohio State University Comprehensive Cancer Center, Columbus, OH, USA.; Pelotonia Institute for Immuno-Oncology, The Ohio State University Comprehensive Cancer Center, 460 W 12th Ave, Columbus, OH, 43210, USA.; Division of Medical Oncology, Department of Internal Medicine, 1800 Cannon Drive, Suite 1335, Columbus, OH, 43210, USA., Kendra K; The Ohio State University Comprehensive Cancer Center, Columbus, OH, USA.; Division of Medical Oncology, Department of Internal Medicine, 1800 Cannon Drive, Suite 1335, Columbus, OH, 43210, USA., Otterson GA; The Ohio State University Comprehensive Cancer Center, Columbus, OH, USA.; Division of Medical Oncology, Department of Internal Medicine, 1800 Cannon Drive, Suite 1335, Columbus, OH, 43210, USA., Presley CJ; The Ohio State University Comprehensive Cancer Center, Columbus, OH, USA.; Division of Medical Oncology, Department of Internal Medicine, 1800 Cannon Drive, Suite 1335, Columbus, OH, 43210, USA., Mace T; The Ohio State University Comprehensive Cancer Center, Columbus, OH, USA.; Division of Gastroenterology, Hepatology, and Nutrition, Department of Internal Medicine, 420 W. 12th Ave, OH, 43210, Columbus, USA., Spakowicz D; The Ohio State University Comprehensive Cancer Center, Columbus, OH, USA. Daniel.Spakowicz@osumc.edu.; Pelotonia Institute for Immuno-Oncology, The Ohio State University Comprehensive Cancer Center, 460 W 12th Ave, Columbus, OH, 43210, USA. Daniel.Spakowicz@osumc.edu.; Division of Medical Oncology, Department of Internal Medicine, 1800 Cannon Drive, Suite 1335, Columbus, OH, 43210, USA. Daniel.Spakowicz@osumc.edu., Owen DH; The Ohio State University Comprehensive Cancer Center, Columbus, OH, USA. Dwight.Owen@osumc.edu.; Pelotonia Institute for Immuno-Oncology, The Ohio State University Comprehensive Cancer Center, 460 W 12th Ave, Columbus, OH, 43210, USA. Dwight.Owen@osumc.edu.; Division of Medical Oncology, Department of Internal Medicine, 1800 Cannon Drive, Suite 1335, Columbus, OH, 43210, USA. Dwight.Owen@osumc.edu. |
| Source: | Cancer immunology, immunotherapy : CII [Cancer Immunol Immunother] 2026 Mar 09; Vol. 75 (4). Date of Electronic Publication: 2026 Mar 09. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Springer Verlag Country of Publication: Germany NLM ID: 8605732 Publication Model: Electronic Cited Medium: Internet ISSN: 1432-0851 (Electronic) Linking ISSN: 03407004 NLM ISO Abbreviation: Cancer Immunol Immunother Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
|
Full text is not displayed to guests.
Login for full access.
|
|
| ISSN: | 1432-0851 |
|---|---|
| DOI: | 10.1007/s00262-026-04346-7 |
