Predictors of glucocorticoid-free clinical remission in patients with newly diagnosed microscopic polyangiitis and granulomatosis with polyangiitis: a retrospective cohort study using a nationwide registry in Japan (J-CANVAS).

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Title: Predictors of glucocorticoid-free clinical remission in patients with newly diagnosed microscopic polyangiitis and granulomatosis with polyangiitis: a retrospective cohort study using a nationwide registry in Japan (J-CANVAS).
Authors: Ushio Y; Division of Hematology, Rheumatology and Respiratory Medicine, Department of Internal Medicine, Faculty of Medicine, Kagawa University, 1750-1 Ikenobe, Miki, Kagawa, 761-0793, Japan., Wakiya R; Division of Hematology, Rheumatology and Respiratory Medicine, Department of Internal Medicine, Faculty of Medicine, Kagawa University, 1750-1 Ikenobe, Miki, Kagawa, 761-0793, Japan., Shimada H; Division of Hematology, Rheumatology and Respiratory Medicine, Department of Internal Medicine, Faculty of Medicine, Kagawa University, 1750-1 Ikenobe, Miki, Kagawa, 761-0793, Japan., Sugihara K; Division of Hematology, Rheumatology and Respiratory Medicine, Department of Internal Medicine, Faculty of Medicine, Kagawa University, 1750-1 Ikenobe, Miki, Kagawa, 761-0793, Japan., Omura S; Inflammation and Immunology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan., Nakagomi D; Department of Rheumatology, University of Yamanashi Hospital, Chuo, Yamanashi, Japan., Abe Y; Department of Internal Medicine and Rheumatology, Juntendo University, Tokyo, Japan., Wada M; Center for Rheumatic Disease, Japanese Red Cross Society Kyoto Daiichi Hospital, Kyoto, Japan., Takizawa N; Department of Rheumatology, Chubu Rosai Hospital, Nagoya, Japan., Nomura A; Immuno-Rheumatology Center, St. Luke's International Hospital, Tokyo, Japan., Kukida Y; Department of Rheumatology, Japanese Red Cross Society Kyoto Daini Hospital, Kyoto, Japan., Kondo N; Department of Nephrology, Kyoto Katsura Hospital, Kyoto, Japan., Takagi H; Department of Hematology and Rheumatology, Kagoshima University Hospital, Kagoshima, Japan., Endo K; Department of General Internal Medicine, Tottori Red Cross Hospital, Tottori, Japan., Hirata S; Department of Clinical Immunology and Rheumatology, Hiroshima University Hospital, Hiroshima, Japan., Azuma N; Department of Diabetes, Endocrinology and Clinical Immunology, Hyogo Medical University School of Medicine, Nishinomiya, Japan., Takeuchi T; Department of Internal Medicine (IV), Osaka Medical and Pharmaceutical University, Takatsuki, Japan., Fukui S; Department of Immunology and Rheumatology, Division of Advanced Preventive Medical Sciences, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan., Kamada K; Department of Rheumatology, Endocrinology and Nephrology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo, Japan., Yanai R; Division of Rheumatology, Department of Medicine, Showa Medical University School of Medicine, Tokyo, Japan., Matsuo Y; Department of Rheumatology, Tokyo Kyosai Hospital, Tokyo, Japan., Shimojima Y; Department of Medicine (Neurology and Rheumatology), Shinshu University School of Medicine, Matsumoto, Japan., Nishioka R; Department of Nephrology and Rheumatology, Graduate School of Medical Science, Kanazawa University, Kanazawa, Japan., Okazaki R; Division of Respiratory Medicine and Rheumatology, Department of Multidisciplinary Internal Medicine, Faculty of Medicine, Tottori University, Yonago, Japan., Takata T; Division of Gastroenterology and Nephrology, Tottori University, Yonago, Japan., Moriyama M; Department of Rheumatology, Shimane University Faculty of Medicine, Izumo, Japan., Takatani A; Rheumatic Disease Center, Sasebo Chuo Hospital, Sasebo, Japan.; Department of Public Health, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan., Miyawaki Y; Department of Nephrology, Rheumatology, Endocrinology and Metabolism, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan., Shirai T; Department of Rheumatology, Tohoku University Hospital, Sendai, Japan., Ito T; Division of Nephrology, Department of Internal Medicine, Teikyo University Chiba Medical Center, Ichihara, Japan., Matsumoto I; Department of Rheumatology, Institute of Medicine, University of Tsukuba, Tsukuba, Japan., Takada T; Department of General Medicine, Shirakawa Satellite for Teaching and Research (STAR), Fukushima Medical University, Shirakawa, Japan., Ito-Ihara T; The Clinical and Translational Research Center, University Hospital, Kyoto Prefectural University of Medicine, Kyoto, Japan., Kida T; Inflammation and Immunology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan., Yajima N; Division of Rheumatology, Department of Medicine, Showa Medical University School of Medicine, Tokyo, Japan., Kawaguchi T; Department of Clinical Assessment, Tokyo University of Pharmacy and Life Sciences, Tokyo, Japan., Kawahito Y; Inflammation and Immunology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan., Dobashi H; Division of Hematology, Rheumatology and Respiratory Medicine, Department of Internal Medicine, Faculty of Medicine, Kagawa University, 1750-1 Ikenobe, Miki, Kagawa, 761-0793, Japan. dobashi.hiroaki@kagawa-u.ac.jp.
Source: Arthritis research & therapy [Arthritis Res Ther] 2026 Mar 10; Vol. 28 (1). Date of Electronic Publication: 2026 Mar 10.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101154438 Publication Model: Electronic Cited Medium: Internet ISSN: 1478-6362 (Electronic) Linking ISSN: 14786354 NLM ISO Abbreviation: Arthritis Res Ther Subsets: MEDLINE; In Process
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  Data: Predictors of glucocorticoid-free clinical remission in patients with newly diagnosed microscopic polyangiitis and granulomatosis with polyangiitis: a retrospective cohort study using a nationwide registry in Japan (J-CANVAS).
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  Data: <searchLink fieldCode="AU" term="%22Ushio+Y%22">Ushio Y</searchLink>; Division of Hematology, Rheumatology and Respiratory Medicine, Department of Internal Medicine, Faculty of Medicine, Kagawa University, 1750-1 Ikenobe, Miki, Kagawa, 761-0793, Japan.<br /><searchLink fieldCode="AU" term="%22Wakiya+R%22">Wakiya R</searchLink>; Division of Hematology, Rheumatology and Respiratory Medicine, Department of Internal Medicine, Faculty of Medicine, Kagawa University, 1750-1 Ikenobe, Miki, Kagawa, 761-0793, Japan.<br /><searchLink fieldCode="AU" term="%22Shimada+H%22">Shimada H</searchLink>; Division of Hematology, Rheumatology and Respiratory Medicine, Department of Internal Medicine, Faculty of Medicine, Kagawa University, 1750-1 Ikenobe, Miki, Kagawa, 761-0793, Japan.<br /><searchLink fieldCode="AU" term="%22Sugihara+K%22">Sugihara K</searchLink>; Division of Hematology, Rheumatology and Respiratory Medicine, Department of Internal Medicine, Faculty of Medicine, Kagawa University, 1750-1 Ikenobe, Miki, Kagawa, 761-0793, Japan.<br /><searchLink fieldCode="AU" term="%22Omura+S%22">Omura S</searchLink>; Inflammation and Immunology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan.<br /><searchLink fieldCode="AU" term="%22Nakagomi+D%22">Nakagomi D</searchLink>; Department of Rheumatology, University of Yamanashi Hospital, Chuo, Yamanashi, Japan.<br /><searchLink fieldCode="AU" term="%22Abe+Y%22">Abe Y</searchLink>; Department of Internal Medicine and Rheumatology, Juntendo University, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Wada+M%22">Wada M</searchLink>; Center for Rheumatic Disease, Japanese Red Cross Society Kyoto Daiichi Hospital, Kyoto, Japan.<br /><searchLink fieldCode="AU" term="%22Takizawa+N%22">Takizawa N</searchLink>; Department of Rheumatology, Chubu Rosai Hospital, Nagoya, Japan.<br /><searchLink fieldCode="AU" term="%22Nomura+A%22">Nomura A</searchLink>; Immuno-Rheumatology Center, St. Luke's International Hospital, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Kukida+Y%22">Kukida Y</searchLink>; Department of Rheumatology, Japanese Red Cross Society Kyoto Daini Hospital, Kyoto, Japan.<br /><searchLink fieldCode="AU" term="%22Kondo+N%22">Kondo N</searchLink>; Department of Nephrology, Kyoto Katsura Hospital, Kyoto, Japan.<br /><searchLink fieldCode="AU" term="%22Takagi+H%22">Takagi H</searchLink>; Department of Hematology and Rheumatology, Kagoshima University Hospital, Kagoshima, Japan.<br /><searchLink fieldCode="AU" term="%22Endo+K%22">Endo K</searchLink>; Department of General Internal Medicine, Tottori Red Cross Hospital, Tottori, Japan.<br /><searchLink fieldCode="AU" term="%22Hirata+S%22">Hirata S</searchLink>; Department of Clinical Immunology and Rheumatology, Hiroshima University Hospital, Hiroshima, Japan.<br /><searchLink fieldCode="AU" term="%22Azuma+N%22">Azuma N</searchLink>; Department of Diabetes, Endocrinology and Clinical Immunology, Hyogo Medical University School of Medicine, Nishinomiya, Japan.<br /><searchLink fieldCode="AU" term="%22Takeuchi+T%22">Takeuchi T</searchLink>; Department of Internal Medicine (IV), Osaka Medical and Pharmaceutical University, Takatsuki, Japan.<br /><searchLink fieldCode="AU" term="%22Fukui+S%22">Fukui S</searchLink>; Department of Immunology and Rheumatology, Division of Advanced Preventive Medical Sciences, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan.<br /><searchLink fieldCode="AU" term="%22Kamada+K%22">Kamada K</searchLink>; Department of Rheumatology, Endocrinology and Nephrology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo, Japan.<br /><searchLink fieldCode="AU" term="%22Yanai+R%22">Yanai R</searchLink>; Division of Rheumatology, Department of Medicine, Showa Medical University School of Medicine, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Matsuo+Y%22">Matsuo Y</searchLink>; Department of Rheumatology, Tokyo Kyosai Hospital, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Shimojima+Y%22">Shimojima Y</searchLink>; Department of Medicine (Neurology and Rheumatology), Shinshu University School of Medicine, Matsumoto, Japan.<br /><searchLink fieldCode="AU" term="%22Nishioka+R%22">Nishioka R</searchLink>; Department of Nephrology and Rheumatology, Graduate School of Medical Science, Kanazawa University, Kanazawa, Japan.<br /><searchLink fieldCode="AU" term="%22Okazaki+R%22">Okazaki R</searchLink>; Division of Respiratory Medicine and Rheumatology, Department of Multidisciplinary Internal Medicine, Faculty of Medicine, Tottori University, Yonago, Japan.<br /><searchLink fieldCode="AU" term="%22Takata+T%22">Takata T</searchLink>; Division of Gastroenterology and Nephrology, Tottori University, Yonago, Japan.<br /><searchLink fieldCode="AU" term="%22Moriyama+M%22">Moriyama M</searchLink>; Department of Rheumatology, Shimane University Faculty of Medicine, Izumo, Japan.<br /><searchLink fieldCode="AU" term="%22Takatani+A%22">Takatani A</searchLink>; Rheumatic Disease Center, Sasebo Chuo Hospital, Sasebo, Japan.; Department of Public Health, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan.<br /><searchLink fieldCode="AU" term="%22Miyawaki+Y%22">Miyawaki Y</searchLink>; Department of Nephrology, Rheumatology, Endocrinology and Metabolism, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan.<br /><searchLink fieldCode="AU" term="%22Shirai+T%22">Shirai T</searchLink>; Department of Rheumatology, Tohoku University Hospital, Sendai, Japan.<br /><searchLink fieldCode="AU" term="%22Ito+T%22">Ito T</searchLink>; Division of Nephrology, Department of Internal Medicine, Teikyo University Chiba Medical Center, Ichihara, Japan.<br /><searchLink fieldCode="AU" term="%22Matsumoto+I%22">Matsumoto I</searchLink>; Department of Rheumatology, Institute of Medicine, University of Tsukuba, Tsukuba, Japan.<br /><searchLink fieldCode="AU" term="%22Takada+T%22">Takada T</searchLink>; Department of General Medicine, Shirakawa Satellite for Teaching and Research (STAR), Fukushima Medical University, Shirakawa, Japan.<br /><searchLink fieldCode="AU" term="%22Ito-Ihara+T%22">Ito-Ihara T</searchLink>; The Clinical and Translational Research Center, University Hospital, Kyoto Prefectural University of Medicine, Kyoto, Japan.<br /><searchLink fieldCode="AU" term="%22Kida+T%22">Kida T</searchLink>; Inflammation and Immunology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan.<br /><searchLink fieldCode="AU" term="%22Yajima+N%22">Yajima N</searchLink>; Division of Rheumatology, Department of Medicine, Showa Medical University School of Medicine, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Kawaguchi+T%22">Kawaguchi T</searchLink>; Department of Clinical Assessment, Tokyo University of Pharmacy and Life Sciences, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Kawahito+Y%22">Kawahito Y</searchLink>; Inflammation and Immunology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan.<br /><searchLink fieldCode="AU" term="%22Dobashi+H%22">Dobashi H</searchLink>; Division of Hematology, Rheumatology and Respiratory Medicine, Department of Internal Medicine, Faculty of Medicine, Kagawa University, 1750-1 Ikenobe, Miki, Kagawa, 761-0793, Japan. dobashi.hiroaki@kagawa-u.ac.jp.
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