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Human neuronal differentiation under Aβ exposure: a single-cell transcriptomic and epigenomic dataset.

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Title: Human neuronal differentiation under Aβ exposure: a single-cell transcriptomic and epigenomic dataset.
Authors: Blanco-Luquin I; Neuroepigenetics Unit-Navarrabiomed, Hospital Universitario de Navarra (HUN), Universidad Pública de Navarra (UPNA), IdiSNA (Navarra Institute for Health Research), C/ Irunlarrea, 3, Pamplona, Navarra, 31008, Spain. iblancol@navarra.es., Martínez-de-Morentin X; Division of Biomedical Sciences, King Abdullah University of Science and Technology (KAUST), Thuwal, 23955, Saudi Arabia. xabier.iribarren@kaust.edu.sa., Vilas-Zornoza A; Advanced Genomics Laboratory, Program of Hemato-Oncology, Center for Applied Medical Research (CIMA), University of Navarra, Pamplona, Spain.; Hemato-Oncology Program, Center for Applied Medical Research (CIMA), IDISNA, University of Navarra, Pamplona, Spain.; Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), Pamplona, Spain., Mouzo D; Centre for Haemato-Oncology, Barts Cancer Institute, Queen Mary University of London, Charterhouse Square, London, EC1M 6BQ, UK., Lopez AL; Neuroepigenetics Unit-Navarrabiomed, Hospital Universitario de Navarra (HUN), Universidad Pública de Navarra (UPNA), IdiSNA (Navarra Institute for Health Research), C/ Irunlarrea, 3, Pamplona, Navarra, 31008, Spain., Macías M; Neuroepigenetics Unit-Navarrabiomed, Hospital Universitario de Navarra (HUN), Universidad Pública de Navarra (UPNA), IdiSNA (Navarra Institute for Health Research), C/ Irunlarrea, 3, Pamplona, Navarra, 31008, Spain., Alignani D; Hemato-Oncology Program, Center for Applied Medical Research (CIMA), IDISNA, University of Navarra, Pamplona, Spain.; Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), Pamplona, Spain., Maillo A; Division of Biomedical Sciences, King Abdullah University of Science and Technology (KAUST), Thuwal, 23955, Saudi Arabia., Gonzalez Alvarez AC; Division of Biomedical Sciences, King Abdullah University of Science and Technology (KAUST), Thuwal, 23955, Saudi Arabia., Ibrahim LA; Division of Biomedical Sciences, King Abdullah University of Science and Technology (KAUST), Thuwal, 23955, Saudi Arabia., Lagani V; Division of Biomedical Sciences, King Abdullah University of Science and Technology (KAUST), Thuwal, 23955, Saudi Arabia.; SDAIA-KAUST Center of Excellence in Data Science and Artificial Intelligence, 4700 Thuwal, Jeddah, 23952, Saudi Arabia., Ramírez N; Oncohematology Research Group, Navarrabiomed, University Hospital of Navarra, Public University of Navarra, Navarra Medical Research Institute (IdiSNA), Pamplona, Spain., Tegner J; Division of Biomedical Sciences, King Abdullah University of Science and Technology (KAUST), Thuwal, 23955, Saudi Arabia.; Unit of Computational Medicine, Department of Medicine, Center for Molecular Medicine, Karolinska Institutet, Karolinska University Hospital, L8:05, SE-171 76, Stockholm, Sweden.; Computer, Electrical and Mathematical Sciences and Engineering Division, King Abdullah University of Science and Technology (KAUST), Thuwal, 23955-6900, Saudi Arabia.; Science for Life Laboratory, Tomtebodavagen 23A, SE-17165, Solna, Sweden., Prósper F; Advanced Genomics Laboratory, Program of Hemato-Oncology, Center for Applied Medical Research (CIMA), University of Navarra, Pamplona, Spain.; Hemato-Oncology Program, Center for Applied Medical Research (CIMA), IDISNA, University of Navarra, Pamplona, Spain.; Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), Pamplona, Spain.; Hematology Department, Clínica Universidad de Navarra, University of Navarra, Pamplona, Spain.; Program of Regenerative Medicine, Centre for Applied Medical Research (CIMA), University of Navarra, Pamplona, 31008, Spain; Instituto de Investigación Sanitaria de Navarra (IdiSNA), Pamplona, 31008, Spain., Mendioroz M; Neuroepigenetics Unit-Navarrabiomed, Hospital Universitario de Navarra (HUN), Universidad Pública de Navarra (UPNA), IdiSNA (Navarra Institute for Health Research), C/ Irunlarrea, 3, Pamplona, Navarra, 31008, Spain. tmendioi@navarra.es.; Department of Neurology, Hospital Universitario de Navarra (HUN) - IdiSNA (Navarra Institute for Health Research), C/ Irunlarrea, 3, Pamplona, Navarra, 31008, Spain. tmendioi@navarra.es., Gomez-Cabrero D; Division of Biomedical Sciences, King Abdullah University of Science and Technology (KAUST), Thuwal, 23955, Saudi Arabia. david.gomezcabrero@kaust.edu.sa.
Source: Scientific data [Sci Data] 2026 Mar 10; Vol. 13 (1). Date of Electronic Publication: 2026 Mar 10.
Publication Type: Journal Article; Dataset
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101640192 Publication Model: Electronic Cited Medium: Internet ISSN: 2052-4463 (Electronic) Linking ISSN: 20524463 NLM ISO Abbreviation: Sci Data Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Human neuronal differentiation under Aβ exposure: a single-cell transcriptomic and epigenomic dataset.
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  Data: <searchLink fieldCode="AU" term="%22Blanco-Luquin+I%22">Blanco-Luquin I</searchLink>; Neuroepigenetics Unit-Navarrabiomed, Hospital Universitario de Navarra (HUN), Universidad Pública de Navarra (UPNA), IdiSNA (Navarra Institute for Health Research), C/ Irunlarrea, 3, Pamplona, Navarra, 31008, Spain. iblancol@navarra.es.<br /><searchLink fieldCode="AU" term="%22Martínez-de-Morentin+X%22">Martínez-de-Morentin X</searchLink>; Division of Biomedical Sciences, King Abdullah University of Science and Technology (KAUST), Thuwal, 23955, Saudi Arabia. xabier.iribarren@kaust.edu.sa.<br /><searchLink fieldCode="AU" term="%22Vilas-Zornoza+A%22">Vilas-Zornoza A</searchLink>; Advanced Genomics Laboratory, Program of Hemato-Oncology, Center for Applied Medical Research (CIMA), University of Navarra, Pamplona, Spain.; Hemato-Oncology Program, Center for Applied Medical Research (CIMA), IDISNA, University of Navarra, Pamplona, Spain.; Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), Pamplona, Spain.<br /><searchLink fieldCode="AU" term="%22Mouzo+D%22">Mouzo D</searchLink>; Centre for Haemato-Oncology, Barts Cancer Institute, Queen Mary University of London, Charterhouse Square, London, EC1M 6BQ, UK.<br /><searchLink fieldCode="AU" term="%22Lopez+AL%22">Lopez AL</searchLink>; Neuroepigenetics Unit-Navarrabiomed, Hospital Universitario de Navarra (HUN), Universidad Pública de Navarra (UPNA), IdiSNA (Navarra Institute for Health Research), C/ Irunlarrea, 3, Pamplona, Navarra, 31008, Spain.<br /><searchLink fieldCode="AU" term="%22Macías+M%22">Macías M</searchLink>; Neuroepigenetics Unit-Navarrabiomed, Hospital Universitario de Navarra (HUN), Universidad Pública de Navarra (UPNA), IdiSNA (Navarra Institute for Health Research), C/ Irunlarrea, 3, Pamplona, Navarra, 31008, Spain.<br /><searchLink fieldCode="AU" term="%22Alignani+D%22">Alignani D</searchLink>; Hemato-Oncology Program, Center for Applied Medical Research (CIMA), IDISNA, University of Navarra, Pamplona, Spain.; Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), Pamplona, Spain.<br /><searchLink fieldCode="AU" term="%22Maillo+A%22">Maillo A</searchLink>; Division of Biomedical Sciences, King Abdullah University of Science and Technology (KAUST), Thuwal, 23955, Saudi Arabia.<br /><searchLink fieldCode="AU" term="%22Gonzalez+Alvarez+AC%22">Gonzalez Alvarez AC</searchLink>; Division of Biomedical Sciences, King Abdullah University of Science and Technology (KAUST), Thuwal, 23955, Saudi Arabia.<br /><searchLink fieldCode="AU" term="%22Ibrahim+LA%22">Ibrahim LA</searchLink>; Division of Biomedical Sciences, King Abdullah University of Science and Technology (KAUST), Thuwal, 23955, Saudi Arabia.<br /><searchLink fieldCode="AU" term="%22Lagani+V%22">Lagani V</searchLink>; Division of Biomedical Sciences, King Abdullah University of Science and Technology (KAUST), Thuwal, 23955, Saudi Arabia.; SDAIA-KAUST Center of Excellence in Data Science and Artificial Intelligence, 4700 Thuwal, Jeddah, 23952, Saudi Arabia.<br /><searchLink fieldCode="AU" term="%22Ramírez+N%22">Ramírez N</searchLink>; Oncohematology Research Group, Navarrabiomed, University Hospital of Navarra, Public University of Navarra, Navarra Medical Research Institute (IdiSNA), Pamplona, Spain.<br /><searchLink fieldCode="AU" term="%22Tegner+J%22">Tegner J</searchLink>; Division of Biomedical Sciences, King Abdullah University of Science and Technology (KAUST), Thuwal, 23955, Saudi Arabia.; Unit of Computational Medicine, Department of Medicine, Center for Molecular Medicine, Karolinska Institutet, Karolinska University Hospital, L8:05, SE-171 76, Stockholm, Sweden.; Computer, Electrical and Mathematical Sciences and Engineering Division, King Abdullah University of Science and Technology (KAUST), Thuwal, 23955-6900, Saudi Arabia.; Science for Life Laboratory, Tomtebodavagen 23A, SE-17165, Solna, Sweden.<br /><searchLink fieldCode="AU" term="%22Prósper+F%22">Prósper F</searchLink>; Advanced Genomics Laboratory, Program of Hemato-Oncology, Center for Applied Medical Research (CIMA), University of Navarra, Pamplona, Spain.; Hemato-Oncology Program, Center for Applied Medical Research (CIMA), IDISNA, University of Navarra, Pamplona, Spain.; Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), Pamplona, Spain.; Hematology Department, Clínica Universidad de Navarra, University of Navarra, Pamplona, Spain.; Program of Regenerative Medicine, Centre for Applied Medical Research (CIMA), University of Navarra, Pamplona, 31008, Spain; Instituto de Investigación Sanitaria de Navarra (IdiSNA), Pamplona, 31008, Spain.<br /><searchLink fieldCode="AU" term="%22Mendioroz+M%22">Mendioroz M</searchLink>; Neuroepigenetics Unit-Navarrabiomed, Hospital Universitario de Navarra (HUN), Universidad Pública de Navarra (UPNA), IdiSNA (Navarra Institute for Health Research), C/ Irunlarrea, 3, Pamplona, Navarra, 31008, Spain. tmendioi@navarra.es.; Department of Neurology, Hospital Universitario de Navarra (HUN) - IdiSNA (Navarra Institute for Health Research), C/ Irunlarrea, 3, Pamplona, Navarra, 31008, Spain. tmendioi@navarra.es.<br /><searchLink fieldCode="AU" term="%22Gomez-Cabrero+D%22">Gomez-Cabrero D</searchLink>; Division of Biomedical Sciences, King Abdullah University of Science and Technology (KAUST), Thuwal, 23955, Saudi Arabia. david.gomezcabrero@kaust.edu.sa.
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