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Stress-relaxing granular bioprinting materials enable complex and uniform organoid self-organization.

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Title: Stress-relaxing granular bioprinting materials enable complex and uniform organoid self-organization.
Authors: Graham AJ; Department of Pharmaceutical Chemistry, University of California San Francisco, San Francisco, CA, USA.; Chan Zuckerberg Biohub SF, San Francisco, CA, USA., Khoo MWL; Chan Zuckerberg Biohub SF, San Francisco, CA, USA., Srivastava V; Department of Pharmaceutical Chemistry, University of California San Francisco, San Francisco, CA, USA., Viragova S; Department of Orofacial Sciences, University of California San Francisco, San Francisco, CA, USA., Kim H; Department of Pharmaceutical Chemistry, University of California San Francisco, San Francisco, CA, USA.; Chan Zuckerberg Biohub SF, San Francisco, CA, USA., Parekh K; Department of Bioengineering, University of California Berkeley, Berkeley, CA, USA., Hennick KM; Weill Institute for Neurosciences, University of California San Francisco, San Francisco, CA, USA., Bird M; Department of Pharmaceutical Chemistry, University of California San Francisco, San Francisco, CA, USA., Goldhammer N; Department of Medicine, University of California San Francisco, San Francisco, CA, USA., Yu JZ; Department of Medicine, University of California San Francisco, San Francisco, CA, USA., Hu G; Graduate Program in Bioengineering, University of California San Francisco and University of California Berkeley, San Francisco, CA, USA., Brinkley NT; Graduate Program in Bioengineering, University of California San Francisco and University of California Berkeley, San Francisco, CA, USA., Pardo L; Graduate Program in Bioengineering, University of California San Francisco and University of California Berkeley, San Francisco, CA, USA., Amaya JS; Department of Bioengineering, University of California Berkeley, Berkeley, CA, USA., Morley CD; Department of Bioengineering, University of California Berkeley, Berkeley, CA, USA., Chadha N; Weill Institute for Neurosciences, University of California San Francisco, San Francisco, CA, USA., Lebel P; Chan Zuckerberg Biohub SF, San Francisco, CA, USA., Kumar S; Department of Bioengineering, University of California Berkeley, Berkeley, CA, USA.; Department of Chemical and Biomolecular Engineering, University of California Berkeley, Berkeley, CA, USA.; Department of Bioengineering and Therapeutic Sciences, University of California San Francisco, San Francisco, CA, USA., Rosenbluth JM; Chan Zuckerberg Biohub SF, San Francisco, CA, USA.; Department of Medicine, University of California San Francisco, San Francisco, CA, USA., Nowakowski TJ; Weill Institute for Neurosciences, University of California San Francisco, San Francisco, CA, USA., Chaudhuri O; Department of Mechanical Engineering, Stanford University, Stanford, CA, USA.; Department of Bioengineering, Stanford University, Stanford, CA, USA., Klein O; Department of Orofacial Sciences, University of California San Francisco, San Francisco, CA, USA.; Department of Pediatrics, Cedars-Sinai Guerin Children's, Los Angeles, CA, USA., Gómez-Sjöberg R; Chan Zuckerberg Biohub SF, San Francisco, CA, USA. rafael.gomez@czbiohub.org., Gartner ZJ; Department of Pharmaceutical Chemistry, University of California San Francisco, San Francisco, CA, USA. zev.gartner@ucsf.edu.; Chan Zuckerberg Biohub SF, San Francisco, CA, USA. zev.gartner@ucsf.edu.; Department of Bioengineering and Therapeutic Sciences, University of California San Francisco, San Francisco, CA, USA. zev.gartner@ucsf.edu.; Center for Cellular Construction, University of California San Francisco, San Francisco, CA, USA. zev.gartner@ucsf.edu.
Source: Nature materials [Nat Mater] 2026 Mar 10. Date of Electronic Publication: 2026 Mar 10.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101155473 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4660 (Electronic) Linking ISSN: 14761122 NLM ISO Abbreviation: Nat Mater Subsets: MEDLINE
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  Data: Stress-relaxing granular bioprinting materials enable complex and uniform organoid self-organization.
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  Data: <searchLink fieldCode="AU" term="%22Graham+AJ%22">Graham AJ</searchLink>; Department of Pharmaceutical Chemistry, University of California San Francisco, San Francisco, CA, USA.; Chan Zuckerberg Biohub SF, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Khoo+MWL%22">Khoo MWL</searchLink>; Chan Zuckerberg Biohub SF, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Srivastava+V%22">Srivastava V</searchLink>; Department of Pharmaceutical Chemistry, University of California San Francisco, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Viragova+S%22">Viragova S</searchLink>; Department of Orofacial Sciences, University of California San Francisco, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Kim+H%22">Kim H</searchLink>; Department of Pharmaceutical Chemistry, University of California San Francisco, San Francisco, CA, USA.; Chan Zuckerberg Biohub SF, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Parekh+K%22">Parekh K</searchLink>; Department of Bioengineering, University of California Berkeley, Berkeley, CA, USA.<br /><searchLink fieldCode="AU" term="%22Hennick+KM%22">Hennick KM</searchLink>; Weill Institute for Neurosciences, University of California San Francisco, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Bird+M%22">Bird M</searchLink>; Department of Pharmaceutical Chemistry, University of California San Francisco, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Goldhammer+N%22">Goldhammer N</searchLink>; Department of Medicine, University of California San Francisco, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Yu+JZ%22">Yu JZ</searchLink>; Department of Medicine, University of California San Francisco, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Hu+G%22">Hu G</searchLink>; Graduate Program in Bioengineering, University of California San Francisco and University of California Berkeley, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Brinkley+NT%22">Brinkley NT</searchLink>; 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Department of Bioengineering, University of California Berkeley, Berkeley, CA, USA.; Department of Chemical and Biomolecular Engineering, University of California Berkeley, Berkeley, CA, USA.; Department of Bioengineering and Therapeutic Sciences, University of California San Francisco, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Rosenbluth+JM%22">Rosenbluth JM</searchLink>; Chan Zuckerberg Biohub SF, San Francisco, CA, USA.; Department of Medicine, University of California San Francisco, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Nowakowski+TJ%22">Nowakowski TJ</searchLink>; Weill Institute for Neurosciences, University of California San Francisco, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Chaudhuri+O%22">Chaudhuri O</searchLink>; Department of Mechanical Engineering, Stanford University, Stanford, CA, USA.; Department of Bioengineering, Stanford University, Stanford, CA, USA.<br /><searchLink fieldCode="AU" term="%22Klein+O%22">Klein O</searchLink>; Department of Orofacial Sciences, University of California San Francisco, San Francisco, CA, USA.; Department of Pediatrics, Cedars-Sinai Guerin Children's, Los Angeles, CA, USA.<br /><searchLink fieldCode="AU" term="%22Gómez-Sjöberg+R%22">Gómez-Sjöberg R</searchLink>; Chan Zuckerberg Biohub SF, San Francisco, CA, USA. rafael.gomez@czbiohub.org.<br /><searchLink fieldCode="AU" term="%22Gartner+ZJ%22">Gartner ZJ</searchLink>; Department of Pharmaceutical Chemistry, University of California San Francisco, San Francisco, CA, USA. zev.gartner@ucsf.edu.; Chan Zuckerberg Biohub SF, San Francisco, CA, USA. zev.gartner@ucsf.edu.; Department of Bioengineering and Therapeutic Sciences, University of California San Francisco, San Francisco, CA, USA. zev.gartner@ucsf.edu.; Center for Cellular Construction, University of California San Francisco, San Francisco, CA, USA. zev.gartner@ucsf.edu.
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