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Dietary folate supplementation modifies effects of arsenic exposure on DNA methylation profiles in sperm of mice expressing the human AS3MT.

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Title: Dietary folate supplementation modifies effects of arsenic exposure on DNA methylation profiles in sperm of mice expressing the human AS3MT.
Authors: Shang B; Department of Nutrition, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, CB# 7461, Chapel Hill, NC, 27599-7461, USA.; Department of Clinical Trial Ward, Clinical Trial and Conversion Center, Shengjing Hospital of China Medical University, Shenyang, Liaoning, China., Douillet C; Department of Nutrition, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, CB# 7461, Chapel Hill, NC, 27599-7461, USA., Hartwell H; Department of Environmental Sciences and Engineering, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, CB# 7431, Chapel Hill, NC, 27599-7431, USA., Miller M; Department of Nutrition, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, CB# 7461, Chapel Hill, NC, 27599-7461, USA., Cable P; Department of Nutrition, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, CB# 7461, Chapel Hill, NC, 27599-7461, USA., Shi Q; Department of Nutrition, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, CB# 7461, Chapel Hill, NC, 27599-7461, USA., Zou F; Department of Biostatistics, Gillings School of Global Public Health, The University of North Carolina at Chapel Hill, Chapel Hill, USA., Krupenko SA; Department of Nutrition, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, CB# 7461, Chapel Hill, NC, 27599-7461, USA.; Nutrition Research Institute, The University of North Carolina at Chapel Hill, Chapel Hill, USA., Ideraabdullah FY; Department of Nutrition, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, CB# 7461, Chapel Hill, NC, 27599-7461, USA.; Department of Genetics, School of Medicine, The University of North Carolina at Chapel Hill, Chapel Hill, USA., de Villena FP; Department of Genetics, School of Medicine, The University of North Carolina at Chapel Hill, Chapel Hill, USA.; Lineberger Comprehensive Cancer Center, School of Medicine, The University of North Carolina at Chapel Hill, Chapel Hill, USA., Fry RC; Department of Environmental Sciences and Engineering, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, CB# 7431, Chapel Hill, NC, 27599-7431, USA. rfry@email.unc.edu., Stýblo M; Department of Nutrition, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, CB# 7461, Chapel Hill, NC, 27599-7461, USA. Styblo@med.unc.edu.
Source: Archives of toxicology [Arch Toxicol] 2026 Jun; Vol. 100 (6), pp. 2323-2335. Date of Electronic Publication: 2026 Mar 10.
Publication Type: Journal Article
Journal Info: Publisher: Springer-Verlag Country of Publication: Germany NLM ID: 0417615 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-0738 (Electronic) Linking ISSN: 03405761 NLM ISO Abbreviation: Arch Toxicol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Dietary folate supplementation modifies effects of arsenic exposure on DNA methylation profiles in sperm of mice expressing the human AS3MT.
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  Data: <searchLink fieldCode="AU" term="%22Shang+B%22">Shang B</searchLink>; Department of Nutrition, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, CB# 7461, Chapel Hill, NC, 27599-7461, USA.; Department of Clinical Trial Ward, Clinical Trial and Conversion Center, Shengjing Hospital of China Medical University, Shenyang, Liaoning, China.<br /><searchLink fieldCode="AU" term="%22Douillet+C%22">Douillet C</searchLink>; Department of Nutrition, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, CB# 7461, Chapel Hill, NC, 27599-7461, USA.<br /><searchLink fieldCode="AU" term="%22Hartwell+H%22">Hartwell H</searchLink>; Department of Environmental Sciences and Engineering, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, CB# 7431, Chapel Hill, NC, 27599-7431, USA.<br /><searchLink fieldCode="AU" term="%22Miller+M%22">Miller M</searchLink>; Department of Nutrition, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, CB# 7461, Chapel Hill, NC, 27599-7461, USA.<br /><searchLink fieldCode="AU" term="%22Cable+P%22">Cable P</searchLink>; Department of Nutrition, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, CB# 7461, Chapel Hill, NC, 27599-7461, USA.<br /><searchLink fieldCode="AU" term="%22Shi+Q%22">Shi Q</searchLink>; Department of Nutrition, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, CB# 7461, Chapel Hill, NC, 27599-7461, USA.<br /><searchLink fieldCode="AU" term="%22Zou+F%22">Zou F</searchLink>; Department of Biostatistics, Gillings School of Global Public Health, The University of North Carolina at Chapel Hill, Chapel Hill, USA.<br /><searchLink fieldCode="AU" term="%22Krupenko+SA%22">Krupenko SA</searchLink>; Department of Nutrition, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, CB# 7461, Chapel Hill, NC, 27599-7461, USA.; Nutrition Research Institute, The University of North Carolina at Chapel Hill, Chapel Hill, USA.<br /><searchLink fieldCode="AU" term="%22Ideraabdullah+FY%22">Ideraabdullah FY</searchLink>; Department of Nutrition, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, CB# 7461, Chapel Hill, NC, 27599-7461, USA.; Department of Genetics, School of Medicine, The University of North Carolina at Chapel Hill, Chapel Hill, USA.<br /><searchLink fieldCode="AU" term="%22de+Villena+FP%22">de Villena FP</searchLink>; Department of Genetics, School of Medicine, The University of North Carolina at Chapel Hill, Chapel Hill, USA.; Lineberger Comprehensive Cancer Center, School of Medicine, The University of North Carolina at Chapel Hill, Chapel Hill, USA.<br /><searchLink fieldCode="AU" term="%22Fry+RC%22">Fry RC</searchLink>; Department of Environmental Sciences and Engineering, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, CB# 7431, Chapel Hill, NC, 27599-7431, USA. rfry@email.unc.edu.<br /><searchLink fieldCode="AU" term="%22Stýblo+M%22">Stýblo M</searchLink>; Department of Nutrition, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, CB# 7461, Chapel Hill, NC, 27599-7461, USA. Styblo@med.unc.edu.
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        Value: 10.1007/s00204-026-04322-1
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              Text: 2026 Jun
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