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Safety and effectiveness of diazepam nasal spray in patients with Rett syndrome and seizure clusters: post hoc analyses from a long-term safety study and survey of severity and burden.

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Title: Safety and effectiveness of diazepam nasal spray in patients with Rett syndrome and seizure clusters: post hoc analyses from a long-term safety study and survey of severity and burden.
Authors: Tarquinio D; Center for Rare Neurological Diseases, Norcross, GA, United States., Wheless JW; Le Bonheur Children's Hospital, University of Tennessee Health Science Center, Memphis, TN, United States., Segal EB; Hackensack University Medical Center and Northeast Regional Epilepsy Group and Hackensack Meridian School of Medicine, Hackensack, NJ, United States., Rabinowicz AL; Neurelis, Inc., San Diego, CA, United States.; Center for Molecular Biology and Biotechnology, Charles E. Schmidt College of Science, Florida Atlantic University, Jupiter, FL, United States., Carrazana E; Neurelis, Inc., San Diego, CA, United States.; John A. Burns School of Medicine, University of Hawaii, Honolulu, HI, United States.
Source: Frontiers in neurology [Front Neurol] 2026 Feb 23; Vol. 17, pp. 1702423. Date of Electronic Publication: 2026 Feb 23 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Research Foundation Country of Publication: Switzerland NLM ID: 101546899 Publication Model: eCollection Cited Medium: Print ISSN: 1664-2295 (Print) Linking ISSN: 16642295 NLM ISO Abbreviation: Front Neurol Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Safety and effectiveness of diazepam nasal spray in patients with Rett syndrome and seizure clusters: post hoc analyses from a long-term safety study and survey of severity and burden.
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  Data: <searchLink fieldCode="AU" term="%22Tarquinio+D%22">Tarquinio D</searchLink>; Center for Rare Neurological Diseases, Norcross, GA, United States.<br /><searchLink fieldCode="AU" term="%22Wheless+JW%22">Wheless JW</searchLink>; Le Bonheur Children's Hospital, University of Tennessee Health Science Center, Memphis, TN, United States.<br /><searchLink fieldCode="AU" term="%22Segal+EB%22">Segal EB</searchLink>; Hackensack University Medical Center and Northeast Regional Epilepsy Group and Hackensack Meridian School of Medicine, Hackensack, NJ, United States.<br /><searchLink fieldCode="AU" term="%22Rabinowicz+AL%22">Rabinowicz AL</searchLink>; Neurelis, Inc., San Diego, CA, United States.; Center for Molecular Biology and Biotechnology, Charles E. Schmidt College of Science, Florida Atlantic University, Jupiter, FL, United States.<br /><searchLink fieldCode="AU" term="%22Carrazana+E%22">Carrazana E</searchLink>; Neurelis, Inc., San Diego, CA, United States.; John A. Burns School of Medicine, University of Hawaii, Honolulu, HI, United States.
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  Data: <searchLink fieldCode="JN" term="%22101546899%22">Frontiers in neurology</searchLink> [Front Neurol] 2026 Feb 23; Vol. 17, pp. 1702423. <i>Date of Electronic Publication: </i>2026 Feb 23 (<i>Print Publication: </i>2026).
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Frontiers+Research+Foundation%22">Frontiers Research Foundation </searchLink><i>Country of Publication: </i>Switzerland <i>NLM ID: </i>101546899 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Print <i>ISSN: </i>1664-2295 (Print) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2216642295%22">16642295 </searchLink><i>NLM ISO Abbreviation: </i>Front Neurol <i>Subsets: </i>PubMed not MEDLINE
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        Value: 10.3389/fneur.2026.1702423
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