View in EDS

Neoadjuvant irradiation of extremity soft tissue sarcoma with ions (Extrem‑ion): Interim report of a randomized phase II pilot trial.

Saved in:
Bibliographic Details
Title: Neoadjuvant irradiation of extremity soft tissue sarcoma with ions (Extrem‑ion): Interim report of a randomized phase II pilot trial.
Authors: Waldsperger H; Department of Radiation Oncology, Heidelberg University Hospital, Heidelberg, Germany; Heidelberg Institute of Radiation Oncology (HIRO), Heidelberg, Germany; National Center for Tumor diseases (NCT), Heidelberg, Germany; Heidelberg Ion-Beam Therapy Center (HIT), Department of Radiation Oncology, Heidelberg University Hospital, Heidelberg, Germany., Lehner B; Center for Orthopedics, Trauma Surgery and Paraplegiology, University of Heidelberg, Heidelberg, Germany., Geisbuesch A; Center for Orthopedics, Trauma Surgery and Paraplegiology, University of Heidelberg, Heidelberg, Germany., Kozyra K; Department of Radiation Oncology, Heidelberg University Hospital, Heidelberg, Germany; Heidelberg Institute of Radiation Oncology (HIRO), Heidelberg, Germany; National Center for Tumor diseases (NCT), Heidelberg, Germany; Heidelberg Ion-Beam Therapy Center (HIT), Department of Radiation Oncology, Heidelberg University Hospital, Heidelberg, Germany., Meixner E; Department of Radiation Oncology, Heidelberg University Hospital, Heidelberg, Germany; Heidelberg Institute of Radiation Oncology (HIRO), Heidelberg, Germany; National Center for Tumor diseases (NCT), Heidelberg, Germany., Baumann L; Institute of Medical Biometry, University of Heidelberg, Germany., Lentz-Hommertgen A; Department of Radiation Oncology, Heidelberg University Hospital, Heidelberg, Germany., Tessonnier T; Department of Radiation Oncology, Heidelberg University Hospital, Heidelberg, Germany; Heidelberg Ion-Beam Therapy Center (HIT), Department of Radiation Oncology, Heidelberg University Hospital, Heidelberg, Germany; Division of Molecular and Translational Radiation Oncology, German Cancer Research Center (DKFZ), Heidelberg, Germany., Mairani A; Department of Radiation Oncology, Heidelberg University Hospital, Heidelberg, Germany; Heidelberg Ion-Beam Therapy Center (HIT), Department of Radiation Oncology, Heidelberg University Hospital, Heidelberg, Germany; Division of Molecular and Translational Radiation Oncology, German Cancer Research Center (DKFZ), Heidelberg, Germany., Mechtersheimer G; Institute of Pathology, Heidelberg University Hospital, Heidelberg, Germany., Egerer G; National Center for Tumor diseases (NCT), Heidelberg, Germany; Department of Hematology, Oncology and Rheumatology, Heidelberg University Hospital, Heidelberg, Germany., Sedlaczek O; Department of Radiology, University of Heidelberg, Heidelberg, Germany; Department of Radiology, German Cancer Research Center (DKFZ), Heidelberg, Germany., Jakob J; Sarcoma Unit, Department of Surgery, University Medical Center Mannheim, University of Heidelberg, Mannheim, Germany., Uhl M; Department of Radiation Oncology, Klinikum Ludwigshafen, Ludwigshafen, Germany., Kieser M; Institute of Medical Biometry, University of Heidelberg, Germany., Herfarth K; Department of Radiation Oncology, Heidelberg University Hospital, Heidelberg, Germany; Heidelberg Institute of Radiation Oncology (HIRO), Heidelberg, Germany; National Center for Tumor diseases (NCT), Heidelberg, Germany; Heidelberg Ion-Beam Therapy Center (HIT), Department of Radiation Oncology, Heidelberg University Hospital, Heidelberg, Germany; German Cancer Consortium (DKTK), partner site Heidelberg, Germany., Debus J; Department of Radiation Oncology, Heidelberg University Hospital, Heidelberg, Germany; Heidelberg Institute of Radiation Oncology (HIRO), Heidelberg, Germany; National Center for Tumor diseases (NCT), Heidelberg, Germany; Clinical Cooperation Unit Radiation Oncology, German Cancer Research Center (DKFZ), Heidelberg, Germany; Heidelberg Ion-Beam Therapy Center (HIT), Department of Radiation Oncology, Heidelberg University Hospital, Heidelberg, Germany; German Cancer Consortium (DKTK), partner site Heidelberg, Germany., Seidensaal K; Department of Radiation Oncology, Heidelberg University Hospital, Heidelberg, Germany; Heidelberg Institute of Radiation Oncology (HIRO), Heidelberg, Germany; National Center for Tumor diseases (NCT), Heidelberg, Germany; Heidelberg Ion-Beam Therapy Center (HIT), Department of Radiation Oncology, Heidelberg University Hospital, Heidelberg, Germany; Institute of Medical Biometry, University of Heidelberg, Germany; ROCC Radiation Oncology Leonberg, Leonberg, Germany. Electronic address: k.seidensaal@yahoo.de.
Source: Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology [Radiother Oncol] 2026 Jun; Vol. 219, pp. 111480. Date of Electronic Publication: 2026 Mar 09.
Publication Type: Journal Article; Clinical Trial, Phase II; Randomized Controlled Trial
Journal Info: Publisher: Elsevier Scientific Publishers Country of Publication: Ireland NLM ID: 8407192 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0887 (Electronic) Linking ISSN: 01678140 NLM ISO Abbreviation: Radiother Oncol Subsets: MEDLINE
Database: MEDLINE Ultimate
FullText Text:
  Availability: 0
Header DbId: mdl
DbLabel: MEDLINE Ultimate
An: 41812864
AccessLevel: 2
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Neoadjuvant irradiation of extremity soft tissue sarcoma with ions (Extrem‑ion): Interim report of a randomized phase II pilot trial.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AU" term="%22Waldsperger+H%22">Waldsperger H</searchLink>; Department of Radiation Oncology, Heidelberg University Hospital, Heidelberg, Germany; Heidelberg Institute of Radiation Oncology (HIRO), Heidelberg, Germany; National Center for Tumor diseases (NCT), Heidelberg, Germany; Heidelberg Ion-Beam Therapy Center (HIT), Department of Radiation Oncology, Heidelberg University Hospital, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Lehner+B%22">Lehner B</searchLink>; Center for Orthopedics, Trauma Surgery and Paraplegiology, University of Heidelberg, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Geisbuesch+A%22">Geisbuesch A</searchLink>; Center for Orthopedics, Trauma Surgery and Paraplegiology, University of Heidelberg, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Kozyra+K%22">Kozyra K</searchLink>; Department of Radiation Oncology, Heidelberg University Hospital, Heidelberg, Germany; Heidelberg Institute of Radiation Oncology (HIRO), Heidelberg, Germany; National Center for Tumor diseases (NCT), Heidelberg, Germany; Heidelberg Ion-Beam Therapy Center (HIT), Department of Radiation Oncology, Heidelberg University Hospital, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Meixner+E%22">Meixner E</searchLink>; Department of Radiation Oncology, Heidelberg University Hospital, Heidelberg, Germany; Heidelberg Institute of Radiation Oncology (HIRO), Heidelberg, Germany; National Center for Tumor diseases (NCT), Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Baumann+L%22">Baumann L</searchLink>; Institute of Medical Biometry, University of Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Lentz-Hommertgen+A%22">Lentz-Hommertgen A</searchLink>; Department of Radiation Oncology, Heidelberg University Hospital, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Tessonnier+T%22">Tessonnier T</searchLink>; Department of Radiation Oncology, Heidelberg University Hospital, Heidelberg, Germany; Heidelberg Ion-Beam Therapy Center (HIT), Department of Radiation Oncology, Heidelberg University Hospital, Heidelberg, Germany; Division of Molecular and Translational Radiation Oncology, German Cancer Research Center (DKFZ), Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Mairani+A%22">Mairani A</searchLink>; Department of Radiation Oncology, Heidelberg University Hospital, Heidelberg, Germany; Heidelberg Ion-Beam Therapy Center (HIT), Department of Radiation Oncology, Heidelberg University Hospital, Heidelberg, Germany; Division of Molecular and Translational Radiation Oncology, German Cancer Research Center (DKFZ), Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Mechtersheimer+G%22">Mechtersheimer G</searchLink>; Institute of Pathology, Heidelberg University Hospital, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Egerer+G%22">Egerer G</searchLink>; National Center for Tumor diseases (NCT), Heidelberg, Germany; Department of Hematology, Oncology and Rheumatology, Heidelberg University Hospital, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Sedlaczek+O%22">Sedlaczek O</searchLink>; Department of Radiology, University of Heidelberg, Heidelberg, Germany; Department of Radiology, German Cancer Research Center (DKFZ), Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Jakob+J%22">Jakob J</searchLink>; Sarcoma Unit, Department of Surgery, University Medical Center Mannheim, University of Heidelberg, Mannheim, Germany.<br /><searchLink fieldCode="AU" term="%22Uhl+M%22">Uhl M</searchLink>; Department of Radiation Oncology, Klinikum Ludwigshafen, Ludwigshafen, Germany.<br /><searchLink fieldCode="AU" term="%22Kieser+M%22">Kieser M</searchLink>; Institute of Medical Biometry, University of Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Herfarth+K%22">Herfarth K</searchLink>; Department of Radiation Oncology, Heidelberg University Hospital, Heidelberg, Germany; Heidelberg Institute of Radiation Oncology (HIRO), Heidelberg, Germany; National Center for Tumor diseases (NCT), Heidelberg, Germany; Heidelberg Ion-Beam Therapy Center (HIT), Department of Radiation Oncology, Heidelberg University Hospital, Heidelberg, Germany; German Cancer Consortium (DKTK), partner site Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Debus+J%22">Debus J</searchLink>; Department of Radiation Oncology, Heidelberg University Hospital, Heidelberg, Germany; Heidelberg Institute of Radiation Oncology (HIRO), Heidelberg, Germany; National Center for Tumor diseases (NCT), Heidelberg, Germany; Clinical Cooperation Unit Radiation Oncology, German Cancer Research Center (DKFZ), Heidelberg, Germany; Heidelberg Ion-Beam Therapy Center (HIT), Department of Radiation Oncology, Heidelberg University Hospital, Heidelberg, Germany; German Cancer Consortium (DKTK), partner site Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Seidensaal+K%22">Seidensaal K</searchLink>; Department of Radiation Oncology, Heidelberg University Hospital, Heidelberg, Germany; Heidelberg Institute of Radiation Oncology (HIRO), Heidelberg, Germany; National Center for Tumor diseases (NCT), Heidelberg, Germany; Heidelberg Ion-Beam Therapy Center (HIT), Department of Radiation Oncology, Heidelberg University Hospital, Heidelberg, Germany; Institute of Medical Biometry, University of Heidelberg, Germany; ROCC Radiation Oncology Leonberg, Leonberg, Germany. Electronic address: k.seidensaal@yahoo.de.
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%228407192%22">Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology</searchLink> [Radiother Oncol] 2026 Jun; Vol. 219, pp. 111480. <i>Date of Electronic Publication: </i>2026 Mar 09.
– Name: TypePub
  Label: Publication Type
  Group: TypPub
  Data: Journal Article; Clinical Trial, Phase II; Randomized Controlled Trial
– Name: TitleSource
  Label: Journal Info
  Group: Src
  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier+Scientific+Publishers%22">Elsevier Scientific Publishers </searchLink><i>Country of Publication: </i>Ireland <i>NLM ID: </i>8407192 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1879-0887 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2201678140%22">01678140 </searchLink><i>NLM ISO Abbreviation: </i>Radiother Oncol <i>Subsets: </i>MEDLINE
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=41812864
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1016/j.radonc.2026.111480
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        StartPage: 111480
    Titles:
      – TitleFull: Neoadjuvant irradiation of extremity soft tissue sarcoma with ions (Extrem‑ion): Interim report of a randomized phase II pilot trial.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Waldsperger H
      – PersonEntity:
          Name:
            NameFull: Lehner B
      – PersonEntity:
          Name:
            NameFull: Geisbuesch A
      – PersonEntity:
          Name:
            NameFull: Kozyra K
      – PersonEntity:
          Name:
            NameFull: Meixner E
      – PersonEntity:
          Name:
            NameFull: Baumann L
      – PersonEntity:
          Name:
            NameFull: Lentz-Hommertgen A
      – PersonEntity:
          Name:
            NameFull: Tessonnier T
      – PersonEntity:
          Name:
            NameFull: Mairani A
      – PersonEntity:
          Name:
            NameFull: Mechtersheimer G
      – PersonEntity:
          Name:
            NameFull: Egerer G
      – PersonEntity:
          Name:
            NameFull: Sedlaczek O
      – PersonEntity:
          Name:
            NameFull: Jakob J
      – PersonEntity:
          Name:
            NameFull: Uhl M
      – PersonEntity:
          Name:
            NameFull: Kieser M
      – PersonEntity:
          Name:
            NameFull: Herfarth K
      – PersonEntity:
          Name:
            NameFull: Debus J
      – PersonEntity:
          Name:
            NameFull: Seidensaal K
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 01
              M: 06
              Text: 2026 Jun
              Type: published
              Y: 2026
          Identifiers:
            – Type: issn-electronic
              Value: 1879-0887
          Numbering:
            – Type: volume
              Value: 219
          Titles:
            – TitleFull: Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
              Type: main
ResultId 1