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Dual and context-dependent role of the interleukin-33/soluble suppression of tumorigenicity 2 axis in obesity and adipose tissue inflammation.

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Title: Dual and context-dependent role of the interleukin-33/soluble suppression of tumorigenicity 2 axis in obesity and adipose tissue inflammation.
Authors: Casado M; Metabolic Research Laboratory, Cancer Center Clínica Universidad de Navarra (CCUN), Avda. Pío XII, 36, Pamplona, 31008, Spain.; Department of Oncology, Clínica Universidad de Navarra, Pamplona, Spain., Gómez-Ambrosi J; Metabolic Research Laboratory, Cancer Center Clínica Universidad de Navarra (CCUN), Avda. Pío XII, 36, Pamplona, 31008, Spain.; Institute for Nutrition and Health, University of Navarra, Pamplona, Spain.; CIBER Fisiopatología de La Obesidad y Nutrición (CIBEROBN), Instituto de Salud Carlos III, Pamplona, Spain.; Obesity and Adipobiology Group, Instituto de Investigación Sanitaria de Navarra (IdiSNA), Pamplona, Spain., Ramírez B; Metabolic Research Laboratory, Cancer Center Clínica Universidad de Navarra (CCUN), Avda. Pío XII, 36, Pamplona, 31008, Spain.; Institute for Nutrition and Health, University of Navarra, Pamplona, Spain.; CIBER Fisiopatología de La Obesidad y Nutrición (CIBEROBN), Instituto de Salud Carlos III, Pamplona, Spain.; Obesity and Adipobiology Group, Instituto de Investigación Sanitaria de Navarra (IdiSNA), Pamplona, Spain., Becerril S; Metabolic Research Laboratory, Cancer Center Clínica Universidad de Navarra (CCUN), Avda. Pío XII, 36, Pamplona, 31008, Spain.; Institute for Nutrition and Health, University of Navarra, Pamplona, Spain.; CIBER Fisiopatología de La Obesidad y Nutrición (CIBEROBN), Instituto de Salud Carlos III, Pamplona, Spain.; Obesity and Adipobiology Group, Instituto de Investigación Sanitaria de Navarra (IdiSNA), Pamplona, Spain., Rodríguez A; Metabolic Research Laboratory, Cancer Center Clínica Universidad de Navarra (CCUN), Avda. Pío XII, 36, Pamplona, 31008, Spain.; Institute for Nutrition and Health, University of Navarra, Pamplona, Spain.; CIBER Fisiopatología de La Obesidad y Nutrición (CIBEROBN), Instituto de Salud Carlos III, Pamplona, Spain.; Obesity and Adipobiology Group, Instituto de Investigación Sanitaria de Navarra (IdiSNA), Pamplona, Spain., Valentí V; Department of Surgery, Clínica Universidad de Navarra, Pamplona, Spain., Moncada R; Department of Anesthesia, Clínica Universidad de Navarra, Pamplona, Spain., Silva C; CIBER Fisiopatología de La Obesidad y Nutrición (CIBEROBN), Instituto de Salud Carlos III, Pamplona, Spain.; Department of Endocrinology & Nutrition, Clínica Universidad de Navarra, Avda. Pío XII, 36, 31008, Pamplona, Spain., Escalada J; CIBER Fisiopatología de La Obesidad y Nutrición (CIBEROBN), Instituto de Salud Carlos III, Pamplona, Spain.; Department of Endocrinology & Nutrition, Clínica Universidad de Navarra, Avda. Pío XII, 36, 31008, Pamplona, Spain., Frühbeck G; Metabolic Research Laboratory, Cancer Center Clínica Universidad de Navarra (CCUN), Avda. Pío XII, 36, Pamplona, 31008, Spain. gfruhbeck@unav.es.; Institute for Nutrition and Health, University of Navarra, Pamplona, Spain. gfruhbeck@unav.es.; CIBER Fisiopatología de La Obesidad y Nutrición (CIBEROBN), Instituto de Salud Carlos III, Pamplona, Spain. gfruhbeck@unav.es.; Obesity and Adipobiology Group, Instituto de Investigación Sanitaria de Navarra (IdiSNA), Pamplona, Spain. gfruhbeck@unav.es.; Department of Endocrinology & Nutrition, Clínica Universidad de Navarra, Avda. Pío XII, 36, 31008, Pamplona, Spain. gfruhbeck@unav.es., Catalán V; Metabolic Research Laboratory, Cancer Center Clínica Universidad de Navarra (CCUN), Avda. Pío XII, 36, Pamplona, 31008, Spain. vcatalan@unav.es.; Institute for Nutrition and Health, University of Navarra, Pamplona, Spain. vcatalan@unav.es.; CIBER Fisiopatología de La Obesidad y Nutrición (CIBEROBN), Instituto de Salud Carlos III, Pamplona, Spain. vcatalan@unav.es.; Obesity and Adipobiology Group, Instituto de Investigación Sanitaria de Navarra (IdiSNA), Pamplona, Spain. vcatalan@unav.es.
Source: Molecular medicine (Cambridge, Mass.) [Mol Med] 2026 Mar 12; Vol. 32 (1). Date of Electronic Publication: 2026 Mar 12.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 9501023 Publication Model: Electronic Cited Medium: Internet ISSN: 1528-3658 (Electronic) Linking ISSN: 10761551 NLM ISO Abbreviation: Mol Med Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Dual and context-dependent role of the interleukin-33/soluble suppression of tumorigenicity 2 axis in obesity and adipose tissue inflammation.
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  Data: <searchLink fieldCode="AU" term="%22Casado+M%22">Casado M</searchLink>; Metabolic Research Laboratory, Cancer Center Clínica Universidad de Navarra (CCUN), Avda. Pío XII, 36, Pamplona, 31008, Spain.; Department of Oncology, Clínica Universidad de Navarra, Pamplona, Spain.<br /><searchLink fieldCode="AU" term="%22Gómez-Ambrosi+J%22">Gómez-Ambrosi J</searchLink>; Metabolic Research Laboratory, Cancer Center Clínica Universidad de Navarra (CCUN), Avda. Pío XII, 36, Pamplona, 31008, Spain.; Institute for Nutrition and Health, University of Navarra, Pamplona, Spain.; CIBER Fisiopatología de La Obesidad y Nutrición (CIBEROBN), Instituto de Salud Carlos III, Pamplona, Spain.; Obesity and Adipobiology Group, Instituto de Investigación Sanitaria de Navarra (IdiSNA), Pamplona, Spain.<br /><searchLink fieldCode="AU" term="%22Ramírez+B%22">Ramírez B</searchLink>; Metabolic Research Laboratory, Cancer Center Clínica Universidad de Navarra (CCUN), Avda. Pío XII, 36, Pamplona, 31008, Spain.; Institute for Nutrition and Health, University of Navarra, Pamplona, Spain.; CIBER Fisiopatología de La Obesidad y Nutrición (CIBEROBN), Instituto de Salud Carlos III, Pamplona, Spain.; Obesity and Adipobiology Group, Instituto de Investigación Sanitaria de Navarra (IdiSNA), Pamplona, Spain.<br /><searchLink fieldCode="AU" term="%22Becerril+S%22">Becerril S</searchLink>; Metabolic Research Laboratory, Cancer Center Clínica Universidad de Navarra (CCUN), Avda. Pío XII, 36, Pamplona, 31008, Spain.; Institute for Nutrition and Health, University of Navarra, Pamplona, Spain.; CIBER Fisiopatología de La Obesidad y Nutrición (CIBEROBN), Instituto de Salud Carlos III, Pamplona, Spain.; Obesity and Adipobiology Group, Instituto de Investigación Sanitaria de Navarra (IdiSNA), Pamplona, Spain.<br /><searchLink fieldCode="AU" term="%22Rodríguez+A%22">Rodríguez A</searchLink>; Metabolic Research Laboratory, Cancer Center Clínica Universidad de Navarra (CCUN), Avda. Pío XII, 36, Pamplona, 31008, Spain.; Institute for Nutrition and Health, University of Navarra, Pamplona, Spain.; CIBER Fisiopatología de La Obesidad y Nutrición (CIBEROBN), Instituto de Salud Carlos III, Pamplona, Spain.; Obesity and Adipobiology Group, Instituto de Investigación Sanitaria de Navarra (IdiSNA), Pamplona, Spain.<br /><searchLink fieldCode="AU" term="%22Valentí+V%22">Valentí V</searchLink>; Department of Surgery, Clínica Universidad de Navarra, Pamplona, Spain.<br /><searchLink fieldCode="AU" term="%22Moncada+R%22">Moncada R</searchLink>; Department of Anesthesia, Clínica Universidad de Navarra, Pamplona, Spain.<br /><searchLink fieldCode="AU" term="%22Silva+C%22">Silva C</searchLink>; CIBER Fisiopatología de La Obesidad y Nutrición (CIBEROBN), Instituto de Salud Carlos III, Pamplona, Spain.; Department of Endocrinology & Nutrition, Clínica Universidad de Navarra, Avda. Pío XII, 36, 31008, Pamplona, Spain.<br /><searchLink fieldCode="AU" term="%22Escalada+J%22">Escalada J</searchLink>; CIBER Fisiopatología de La Obesidad y Nutrición (CIBEROBN), Instituto de Salud Carlos III, Pamplona, Spain.; Department of Endocrinology & Nutrition, Clínica Universidad de Navarra, Avda. Pío XII, 36, 31008, Pamplona, Spain.<br /><searchLink fieldCode="AU" term="%22Frühbeck+G%22">Frühbeck G</searchLink>; Metabolic Research Laboratory, Cancer Center Clínica Universidad de Navarra (CCUN), Avda. Pío XII, 36, Pamplona, 31008, Spain. gfruhbeck@unav.es.; Institute for Nutrition and Health, University of Navarra, Pamplona, Spain. gfruhbeck@unav.es.; CIBER Fisiopatología de La Obesidad y Nutrición (CIBEROBN), Instituto de Salud Carlos III, Pamplona, Spain. gfruhbeck@unav.es.; Obesity and Adipobiology Group, Instituto de Investigación Sanitaria de Navarra (IdiSNA), Pamplona, Spain. gfruhbeck@unav.es.; Department of Endocrinology & Nutrition, Clínica Universidad de Navarra, Avda. Pío XII, 36, 31008, Pamplona, Spain. gfruhbeck@unav.es.<br /><searchLink fieldCode="AU" term="%22Catalán+V%22">Catalán V</searchLink>; Metabolic Research Laboratory, Cancer Center Clínica Universidad de Navarra (CCUN), Avda. Pío XII, 36, Pamplona, 31008, Spain. vcatalan@unav.es.; Institute for Nutrition and Health, University of Navarra, Pamplona, Spain. vcatalan@unav.es.; CIBER Fisiopatología de La Obesidad y Nutrición (CIBEROBN), Instituto de Salud Carlos III, Pamplona, Spain. vcatalan@unav.es.; Obesity and Adipobiology Group, Instituto de Investigación Sanitaria de Navarra (IdiSNA), Pamplona, Spain. vcatalan@unav.es.
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  Data: <searchLink fieldCode="JN" term="%229501023%22">Molecular medicine (Cambridge, Mass.)</searchLink> [Mol Med] 2026 Mar 12; Vol. 32 (1). <i>Date of Electronic Publication: </i>2026 Mar 12.
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