Safety and effectiveness of a portable nasal high-flow device for improving exercise tolerance in patients with chronic obstructive pulmonary disease: a study protocol for an open-label, randomized, crossover pilot trial.
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| Title: | Safety and effectiveness of a portable nasal high-flow device for improving exercise tolerance in patients with chronic obstructive pulmonary disease: a study protocol for an open-label, randomized, crossover pilot trial. |
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| Authors: | Fukushima C; Clinical Research Center, Nagasaki University Hospital, Nagasaki, Japan.; Department of Respiratory Medicine, Nagasaki University Hospital, Nagasaki, Japan., Fukahori S; Department of Respiratory Medicine, Nagasaki University Hospital, Nagasaki, Japan., Iriki J; Department of Respiratory Medicine, Nagasaki University Hospital, Nagasaki, Japan.; Department of Respiratory Medicine, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan., Tsukamoto Y; Department of Respiratory Medicine, Nagasaki University Hospital, Nagasaki, Japan., Obase Y; Department of Respiratory Medicine, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan.; Department of Respiratory Medicine, Sasebo City General Hospital, Nagasaki, Japan., Kozu R; Department of Rehabilitation Medicine, Nagasaki University Hospital, Nagasaki, Japan.; Department of Physical Therapy Science, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan., Yanagita Y; Department of Rehabilitation Medicine, Nagasaki University Hospital, Nagasaki, Japan.; Department of Physical Therapy Science, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan., Ayuse T; Clinical Research Center, Nagasaki University Hospital, Nagasaki, Japan., Hosogaya N; Clinical Research Center, Nagasaki University Hospital, Nagasaki, Japan.; Department of Respiratory Medicine, Nagasaki University Hospital, Nagasaki, Japan., Hanada M; Department of Rehabilitation Medicine, Nagasaki University Hospital, Nagasaki, Japan.; Department of Physical Therapy Science, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan., Oikawa M; Department of Rehabilitation Medicine, Nagasaki University Hospital, Nagasaki, Japan.; Department of Physical Therapy Science, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan., Kawazoe Y; Clinical Research Center, Nagasaki University Hospital, Nagasaki, Japan., Takemoto S; Department of Respiratory Medicine, Nagasaki University Hospital, Nagasaki, Japan., Takazono T; Department of Respiratory Medicine, Nagasaki University Hospital, Nagasaki, Japan.; Department of Infectious Diseases, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan., Sakamoto N; Department of Respiratory Medicine, Nagasaki University Hospital, Nagasaki, Japan.; Department of Respiratory Medicine, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan., Nishino T; Department of Nephrology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan., Mukae H; Department of Respiratory Medicine, Nagasaki University Hospital, Nagasaki, Japan.; Department of Respiratory Medicine, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan. |
| Source: | Journal of thoracic disease [J Thorac Dis] 2026 Feb 28; Vol. 18 (2), pp. 175. Date of Electronic Publication: 2026 Feb 02. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: AME Publishing Company Country of Publication: China NLM ID: 101533916 Publication Model: Print-Electronic Cited Medium: Print ISSN: 2072-1439 (Print) Linking ISSN: 20721439 NLM ISO Abbreviation: J Thorac Dis Subsets: PubMed not MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 41816455 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Safety and effectiveness of a portable nasal high-flow device for improving exercise tolerance in patients with chronic obstructive pulmonary disease: a study protocol for an open-label, randomized, crossover pilot trial. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Fukushima+C%22">Fukushima C</searchLink>; Clinical Research Center, Nagasaki University Hospital, Nagasaki, Japan.; Department of Respiratory Medicine, Nagasaki University Hospital, Nagasaki, Japan.<br /><searchLink fieldCode="AU" term="%22Fukahori+S%22">Fukahori S</searchLink>; Department of Respiratory Medicine, Nagasaki University Hospital, Nagasaki, Japan.<br /><searchLink fieldCode="AU" term="%22Iriki+J%22">Iriki J</searchLink>; Department of Respiratory Medicine, Nagasaki University Hospital, Nagasaki, Japan.; Department of Respiratory Medicine, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan.<br /><searchLink fieldCode="AU" term="%22Tsukamoto+Y%22">Tsukamoto Y</searchLink>; Department of Respiratory Medicine, Nagasaki University Hospital, Nagasaki, Japan.<br /><searchLink fieldCode="AU" term="%22Obase+Y%22">Obase Y</searchLink>; Department of Respiratory Medicine, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan.; Department of Respiratory Medicine, Sasebo City General Hospital, Nagasaki, Japan.<br /><searchLink fieldCode="AU" term="%22Kozu+R%22">Kozu R</searchLink>; Department of Rehabilitation Medicine, Nagasaki University Hospital, Nagasaki, Japan.; Department of Physical Therapy Science, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan.<br /><searchLink fieldCode="AU" term="%22Yanagita+Y%22">Yanagita Y</searchLink>; Department of Rehabilitation Medicine, Nagasaki University Hospital, Nagasaki, Japan.; Department of Physical Therapy Science, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan.<br /><searchLink fieldCode="AU" term="%22Ayuse+T%22">Ayuse T</searchLink>; Clinical Research Center, Nagasaki University Hospital, Nagasaki, Japan.<br /><searchLink fieldCode="AU" term="%22Hosogaya+N%22">Hosogaya N</searchLink>; Clinical Research Center, Nagasaki University Hospital, Nagasaki, Japan.; Department of Respiratory Medicine, Nagasaki University Hospital, Nagasaki, Japan.<br /><searchLink fieldCode="AU" term="%22Hanada+M%22">Hanada M</searchLink>; Department of Rehabilitation Medicine, Nagasaki University Hospital, Nagasaki, Japan.; Department of Physical Therapy Science, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan.<br /><searchLink fieldCode="AU" term="%22Oikawa+M%22">Oikawa M</searchLink>; Department of Rehabilitation Medicine, Nagasaki University Hospital, Nagasaki, Japan.; Department of Physical Therapy Science, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan.<br /><searchLink fieldCode="AU" term="%22Kawazoe+Y%22">Kawazoe Y</searchLink>; Clinical Research Center, Nagasaki University Hospital, Nagasaki, Japan.<br /><searchLink fieldCode="AU" term="%22Takemoto+S%22">Takemoto S</searchLink>; Department of Respiratory Medicine, Nagasaki University Hospital, Nagasaki, Japan.<br /><searchLink fieldCode="AU" term="%22Takazono+T%22">Takazono T</searchLink>; Department of Respiratory Medicine, Nagasaki University Hospital, Nagasaki, Japan.; Department of Infectious Diseases, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan.<br /><searchLink fieldCode="AU" term="%22Sakamoto+N%22">Sakamoto N</searchLink>; Department of Respiratory Medicine, Nagasaki University Hospital, Nagasaki, Japan.; Department of Respiratory Medicine, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan.<br /><searchLink fieldCode="AU" term="%22Nishino+T%22">Nishino T</searchLink>; Department of Nephrology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan.<br /><searchLink fieldCode="AU" term="%22Mukae+H%22">Mukae H</searchLink>; Department of Respiratory Medicine, Nagasaki University Hospital, Nagasaki, Japan.; Department of Respiratory Medicine, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22101533916%22">Journal of thoracic disease</searchLink> [J Thorac Dis] 2026 Feb 28; Vol. 18 (2), pp. 175. <i>Date of Electronic Publication: </i>2026 Feb 02. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22AME+Publishing+Company%22">AME Publishing Company </searchLink><i>Country of Publication: </i>China <i>NLM ID: </i>101533916 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Print <i>ISSN: </i>2072-1439 (Print) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2220721439%22">20721439 </searchLink><i>NLM ISO Abbreviation: </i>J Thorac Dis <i>Subsets: </i>PubMed not MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=41816455 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.21037/jtd-2025-aw-2316 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 175 Titles: – TitleFull: Safety and effectiveness of a portable nasal high-flow device for improving exercise tolerance in patients with chronic obstructive pulmonary disease: a study protocol for an open-label, randomized, crossover pilot trial. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Fukushima C – PersonEntity: Name: NameFull: Fukahori S – PersonEntity: Name: NameFull: Iriki J – PersonEntity: Name: NameFull: Tsukamoto Y – PersonEntity: Name: NameFull: Obase Y – PersonEntity: Name: NameFull: Kozu R – PersonEntity: Name: NameFull: Yanagita Y – PersonEntity: Name: NameFull: Ayuse T – PersonEntity: Name: NameFull: Hosogaya N – PersonEntity: Name: NameFull: Hanada M – PersonEntity: Name: NameFull: Oikawa M – PersonEntity: Name: NameFull: Kawazoe Y – PersonEntity: Name: NameFull: Takemoto S – PersonEntity: Name: NameFull: Takazono T – PersonEntity: Name: NameFull: Sakamoto N – PersonEntity: Name: NameFull: Nishino T – PersonEntity: Name: NameFull: Mukae H IsPartOfRelationships: – BibEntity: Dates: – D: 28 M: 02 Text: 2026 Feb 28 Type: published Y: 2026 Identifiers: – Type: issn-print Value: 2072-1439 Numbering: – Type: volume Value: 18 – Type: issue Value: 2 Titles: – TitleFull: Journal of thoracic disease Type: main |
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