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Effects of in vitro fermentation of Astragalus polysaccharide on gut microbiota and neurotransmitter metabolites in patients with major depressive disorder.

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Title: Effects of in vitro fermentation of Astragalus polysaccharide on gut microbiota and neurotransmitter metabolites in patients with major depressive disorder.
Authors: Lin C; Department of Psychosomatic Medicine, The First Affiliated Hospital of Ningbo University, Ningbo, Zhejiang, China., Mi YW; Department of Psychosomatic Medicine, The First Affiliated Hospital of Ningbo University, Ningbo, Zhejiang, China., Zheng HW; State Key Laboratory for Managing Biotic and Chemical Threats to the Quality and Safety of Agro-products, Zhejiang Academy of Agricultural Sciences, Hangzhou, Zhejiang, China., Hou YB; Department of Psychosomatic Medicine, The First Affiliated Hospital of Ningbo University, Ningbo, Zhejiang, China., Hu JQ; Department of Psychosomatic Medicine, The First Affiliated Hospital of Ningbo University, Ningbo, Zhejiang, China., Mao JX; Department of Psychosomatic Medicine, The First Affiliated Hospital of Ningbo University, Ningbo, Zhejiang, China., Dai N; Department of Psychosomatic Medicine, The First Affiliated Hospital of Ningbo University, Ningbo, Zhejiang, China., Fu CL; Rehabilitation Department, The People's Hospital of Ningbo Haishu District, Ningbo, Zhejiang, China., Li XQ; State Key Laboratory for Managing Biotic and Chemical Threats to the Quality and Safety of Agro-products, Zhejiang Academy of Agricultural Sciences, Hangzhou, Zhejiang, China., Ji YX; Department of Psychosomatic Medicine, The First Affiliated Hospital of Ningbo University, Ningbo, Zhejiang, China.
Source: Frontiers in psychiatry [Front Psychiatry] 2026 Feb 25; Vol. 17, pp. 1752933. Date of Electronic Publication: 2026 Feb 25 (Print Publication: 2026).
Publication Type: Clinical Trial; Journal Article
Journal Info: Publisher: Frontiers Research Foundation Country of Publication: Switzerland NLM ID: 101545006 Publication Model: eCollection Cited Medium: Print ISSN: 1664-0640 (Print) Linking ISSN: 16640640 NLM ISO Abbreviation: Front Psychiatry Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Effects of in vitro fermentation of Astragalus polysaccharide on gut microbiota and neurotransmitter metabolites in patients with major depressive disorder.
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  Data: <searchLink fieldCode="AU" term="%22Lin+C%22">Lin C</searchLink>; Department of Psychosomatic Medicine, The First Affiliated Hospital of Ningbo University, Ningbo, Zhejiang, China.<br /><searchLink fieldCode="AU" term="%22Mi+YW%22">Mi YW</searchLink>; Department of Psychosomatic Medicine, The First Affiliated Hospital of Ningbo University, Ningbo, Zhejiang, China.<br /><searchLink fieldCode="AU" term="%22Zheng+HW%22">Zheng HW</searchLink>; State Key Laboratory for Managing Biotic and Chemical Threats to the Quality and Safety of Agro-products, Zhejiang Academy of Agricultural Sciences, Hangzhou, Zhejiang, China.<br /><searchLink fieldCode="AU" term="%22Hou+YB%22">Hou YB</searchLink>; Department of Psychosomatic Medicine, The First Affiliated Hospital of Ningbo University, Ningbo, Zhejiang, China.<br /><searchLink fieldCode="AU" term="%22Hu+JQ%22">Hu JQ</searchLink>; Department of Psychosomatic Medicine, The First Affiliated Hospital of Ningbo University, Ningbo, Zhejiang, China.<br /><searchLink fieldCode="AU" term="%22Mao+JX%22">Mao JX</searchLink>; Department of Psychosomatic Medicine, The First Affiliated Hospital of Ningbo University, Ningbo, Zhejiang, China.<br /><searchLink fieldCode="AU" term="%22Dai+N%22">Dai N</searchLink>; Department of Psychosomatic Medicine, The First Affiliated Hospital of Ningbo University, Ningbo, Zhejiang, China.<br /><searchLink fieldCode="AU" term="%22Fu+CL%22">Fu CL</searchLink>; Rehabilitation Department, The People's Hospital of Ningbo Haishu District, Ningbo, Zhejiang, China.<br /><searchLink fieldCode="AU" term="%22Li+XQ%22">Li XQ</searchLink>; State Key Laboratory for Managing Biotic and Chemical Threats to the Quality and Safety of Agro-products, Zhejiang Academy of Agricultural Sciences, Hangzhou, Zhejiang, China.<br /><searchLink fieldCode="AU" term="%22Ji+YX%22">Ji YX</searchLink>; Department of Psychosomatic Medicine, The First Affiliated Hospital of Ningbo University, Ningbo, Zhejiang, China.
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  Data: <searchLink fieldCode="JN" term="%22101545006%22">Frontiers in psychiatry</searchLink> [Front Psychiatry] 2026 Feb 25; Vol. 17, pp. 1752933. <i>Date of Electronic Publication: </i>2026 Feb 25 (<i>Print Publication: </i>2026).
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Frontiers+Research+Foundation%22">Frontiers Research Foundation </searchLink><i>Country of Publication: </i>Switzerland <i>NLM ID: </i>101545006 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Print <i>ISSN: </i>1664-0640 (Print) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2216640640%22">16640640 </searchLink><i>NLM ISO Abbreviation: </i>Front Psychiatry <i>Subsets: </i>PubMed not MEDLINE
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              Text: 2026 Feb 25
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