PARKIN overexpression confers cardioprotection via suppressing the mtDNA-cGAS-STING axis in myocardial ischemia/reperfusion injury.
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| Title: | PARKIN overexpression confers cardioprotection via suppressing the mtDNA-cGAS-STING axis in myocardial ischemia/reperfusion injury. |
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| Authors: | Li Y; School of Life Sciences, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, 230026, China.; State Key Laboratory of Organ Regeneration and Reconstruction, Institute of Zoology, Chinese Academy of Sciences, Beijing, 100101, China.; Beijing Institute for Stem Cell and Regenerative Medicine, Beijing, 100101, China., Wang Y; State Key Laboratory of Organ Regeneration and Reconstruction, Institute of Zoology, Chinese Academy of Sciences, Beijing, 100101, China.; Beijing Institute for Stem Cell and Regenerative Medicine, Beijing, 100101, China.; University of Chinese Academy of Sciences, Beijing, 100049, China., Zhang H; State Key Laboratory of Organ Regeneration and Reconstruction, Institute of Zoology, Chinese Academy of Sciences, Beijing, 100101, China.; Beijing Institute for Stem Cell and Regenerative Medicine, Beijing, 100101, China.; University of Chinese Academy of Sciences, Beijing, 100049, China., Xu P; State Key Laboratory of Organ Regeneration and Reconstruction, Institute of Zoology, Chinese Academy of Sciences, Beijing, 100101, China.; Beijing Institute for Stem Cell and Regenerative Medicine, Beijing, 100101, China.; University of Chinese Academy of Sciences, Beijing, 100049, China., Yuan X; State Key Laboratory of Organ Regeneration and Reconstruction, Institute of Zoology, Chinese Academy of Sciences, Beijing, 100101, China.; Beijing Institute for Stem Cell and Regenerative Medicine, Beijing, 100101, China.; University of Chinese Academy of Sciences, Beijing, 100049, China., Yuan H; State Key Laboratory of Organ Regeneration and Reconstruction, Institute of Zoology, Chinese Academy of Sciences, Beijing, 100101, China.; Beijing Institute for Stem Cell and Regenerative Medicine, Beijing, 100101, China.; University of Chinese Academy of Sciences, Beijing, 100049, China., Yang C; State Key Laboratory of Organ Regeneration and Reconstruction, Institute of Zoology, Chinese Academy of Sciences, Beijing, 100101, China.; Beijing Institute for Stem Cell and Regenerative Medicine, Beijing, 100101, China.; University of Chinese Academy of Sciences, Beijing, 100049, China., Zhou Y; State Key Laboratory of Organ Regeneration and Reconstruction, Institute of Zoology, Chinese Academy of Sciences, Beijing, 100101, China.; Beijing Institute for Stem Cell and Regenerative Medicine, Beijing, 100101, China.; University of Chinese Academy of Sciences, Beijing, 100049, China., Shen J; State Key Laboratory of Organ Regeneration and Reconstruction, Institute of Zoology, Chinese Academy of Sciences, Beijing, 100101, China.; Beijing Institute for Stem Cell and Regenerative Medicine, Beijing, 100101, China.; University of Chinese Academy of Sciences, Beijing, 100049, China., Du H; State Key Laboratory of Organ Regeneration and Reconstruction, Institute of Zoology, Chinese Academy of Sciences, Beijing, 100101, China.; Beijing Institute for Stem Cell and Regenerative Medicine, Beijing, 100101, China.; University of Chinese Academy of Sciences, Beijing, 100049, China., Gao Z; State Key Laboratory of Organ Regeneration and Reconstruction, Institute of Zoology, Chinese Academy of Sciences, Beijing, 100101, China.; Beijing Institute for Stem Cell and Regenerative Medicine, Beijing, 100101, China., Zang J; State Key Laboratory of Organ Regeneration and Reconstruction, Institute of Zoology, Chinese Academy of Sciences, Beijing, 100101, China.; Beijing Institute for Stem Cell and Regenerative Medicine, Beijing, 100101, China., Liang S; Department of Cardiology, Beijing Friendship Hospital, Capital Medical University, Beijing, 100050, China. simondoctor@163.com., Qu J; School of Life Sciences, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, 230026, China. qujing@ioz.ac.cn.; State Key Laboratory of Organ Regeneration and Reconstruction, Institute of Zoology, Chinese Academy of Sciences, Beijing, 100101, China. qujing@ioz.ac.cn.; Beijing Institute for Stem Cell and Regenerative Medicine, Beijing, 100101, China. qujing@ioz.ac.cn.; University of Chinese Academy of Sciences, Beijing, 100049, China. qujing@ioz.ac.cn., Song M; State Key Laboratory of Organ Regeneration and Reconstruction, Institute of Zoology, Chinese Academy of Sciences, Beijing, 100101, China. songmoshi@ioz.ac.cn.; Beijing Institute for Stem Cell and Regenerative Medicine, Beijing, 100101, China. songmoshi@ioz.ac.cn.; University of Chinese Academy of Sciences, Beijing, 100049, China. songmoshi@ioz.ac.cn. |
| Source: | Basic research in cardiology [Basic Res Cardiol] 2026 Jun; Vol. 121 (3), pp. 395-412. Date of Electronic Publication: 2026 Mar 13. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Steinkopff Country of Publication: Germany NLM ID: 0360342 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1435-1803 (Electronic) Linking ISSN: 03008428 NLM ISO Abbreviation: Basic Res Cardiol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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