APOE-mediated sex differences in microvascular pathology and AD-associated proteinopathies in the medial temporal lobe.

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Title: APOE-mediated sex differences in microvascular pathology and AD-associated proteinopathies in the medial temporal lobe.
Authors: Bax F; J. Philip Kistler Stroke Research Center, Department of Neurology, Harvard Medical School, Massachusetts General Hospital, Boston, Massachusetts, USA.; Clinical Neurology Unit, Department of Head, Neck and Neurosciences, Udine University Hospital, Udine, Italy., Oltmer J; BetterDoc GmbH, Cologne, Germany., Auger CA; MassGeneral Institute for Neurodegenerative Disease, Massachusetts General Hospital, Charlestown, Massachusetts, USA.; Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA., Bonkhoff A; J. Philip Kistler Stroke Research Center, Department of Neurology, Harvard Medical School, Massachusetts General Hospital, Boston, Massachusetts, USA., Coughlan GT; Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA., Melloni A; MassGeneral Institute for Neurodegenerative Disease, Massachusetts General Hospital, Charlestown, Massachusetts, USA.; C.S. Kubik Laboratory for Neuropathology, Neuropathology Service, Harvard Medical School, Massachusetts General Hospital, Boston, Massachusetts, USA., Jaisa-Aad M; MassGeneral Institute for Neurodegenerative Disease, Massachusetts General Hospital, Charlestown, Massachusetts, USA.; Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA., Augustinack J; MassGeneral Institute for Neurodegenerative Disease, Massachusetts General Hospital, Charlestown, Massachusetts, USA., Serrano-Pozo A; MassGeneral Institute for Neurodegenerative Disease, Massachusetts General Hospital, Charlestown, Massachusetts, USA.; Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA., Frosch MP; C.S. Kubik Laboratory for Neuropathology, Neuropathology Service, Harvard Medical School, Massachusetts General Hospital, Boston, Massachusetts, USA., Greenberg SM; J. Philip Kistler Stroke Research Center, Department of Neurology, Harvard Medical School, Massachusetts General Hospital, Boston, Massachusetts, USA., Gomez-Isla T; MassGeneral Institute for Neurodegenerative Disease, Massachusetts General Hospital, Charlestown, Massachusetts, USA.; Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA., Hyman BT; MassGeneral Institute for Neurodegenerative Disease, Massachusetts General Hospital, Charlestown, Massachusetts, USA.; Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA., van Veluw SJ; J. Philip Kistler Stroke Research Center, Department of Neurology, Harvard Medical School, Massachusetts General Hospital, Boston, Massachusetts, USA.; MassGeneral Institute for Neurodegenerative Disease, Massachusetts General Hospital, Charlestown, Massachusetts, USA.; British Heart Foundation - UK Dementia Research Institute Centre for Vascular Dementia Research, The University of Edinburgh, Edinburgh, UK., Perosa V; J. Philip Kistler Stroke Research Center, Department of Neurology, Harvard Medical School, Massachusetts General Hospital, Boston, Massachusetts, USA.
Source: Alzheimer's & dementia : the journal of the Alzheimer's Association [Alzheimers Dement] 2026 Mar; Vol. 22 (3), pp. e71206.
Publication Type: Journal Article
Journal Info: Publisher: John Wiley & Sons, Ltd Country of Publication: United States NLM ID: 101231978 Publication Model: Print Cited Medium: Internet ISSN: 1552-5279 (Electronic) Linking ISSN: 15525260 NLM ISO Abbreviation: Alzheimers Dement Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: APOE-mediated sex differences in microvascular pathology and AD-associated proteinopathies in the medial temporal lobe.
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  Data: <searchLink fieldCode="AU" term="%22Bax+F%22">Bax F</searchLink>; J. Philip Kistler Stroke Research Center, Department of Neurology, Harvard Medical School, Massachusetts General Hospital, Boston, Massachusetts, USA.; Clinical Neurology Unit, Department of Head, Neck and Neurosciences, Udine University Hospital, Udine, Italy.<br /><searchLink fieldCode="AU" term="%22Oltmer+J%22">Oltmer J</searchLink>; BetterDoc GmbH, Cologne, Germany.<br /><searchLink fieldCode="AU" term="%22Auger+CA%22">Auger CA</searchLink>; MassGeneral Institute for Neurodegenerative Disease, Massachusetts General Hospital, Charlestown, Massachusetts, USA.; Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Bonkhoff+A%22">Bonkhoff A</searchLink>; J. Philip Kistler Stroke Research Center, Department of Neurology, Harvard Medical School, Massachusetts General Hospital, Boston, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Coughlan+GT%22">Coughlan GT</searchLink>; Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Melloni+A%22">Melloni A</searchLink>; MassGeneral Institute for Neurodegenerative Disease, Massachusetts General Hospital, Charlestown, Massachusetts, USA.; C.S. Kubik Laboratory for Neuropathology, Neuropathology Service, Harvard Medical School, Massachusetts General Hospital, Boston, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Jaisa-Aad+M%22">Jaisa-Aad M</searchLink>; MassGeneral Institute for Neurodegenerative Disease, Massachusetts General Hospital, Charlestown, Massachusetts, USA.; Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Augustinack+J%22">Augustinack J</searchLink>; MassGeneral Institute for Neurodegenerative Disease, Massachusetts General Hospital, Charlestown, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Serrano-Pozo+A%22">Serrano-Pozo A</searchLink>; MassGeneral Institute for Neurodegenerative Disease, Massachusetts General Hospital, Charlestown, Massachusetts, USA.; Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Frosch+MP%22">Frosch MP</searchLink>; C.S. Kubik Laboratory for Neuropathology, Neuropathology Service, Harvard Medical School, Massachusetts General Hospital, Boston, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Greenberg+SM%22">Greenberg SM</searchLink>; J. Philip Kistler Stroke Research Center, Department of Neurology, Harvard Medical School, Massachusetts General Hospital, Boston, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Gomez-Isla+T%22">Gomez-Isla T</searchLink>; MassGeneral Institute for Neurodegenerative Disease, Massachusetts General Hospital, Charlestown, Massachusetts, USA.; Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Hyman+BT%22">Hyman BT</searchLink>; MassGeneral Institute for Neurodegenerative Disease, Massachusetts General Hospital, Charlestown, Massachusetts, USA.; Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22van+Veluw+SJ%22">van Veluw SJ</searchLink>; J. Philip Kistler Stroke Research Center, Department of Neurology, Harvard Medical School, Massachusetts General Hospital, Boston, Massachusetts, USA.; MassGeneral Institute for Neurodegenerative Disease, Massachusetts General Hospital, Charlestown, Massachusetts, USA.; British Heart Foundation - UK Dementia Research Institute Centre for Vascular Dementia Research, The University of Edinburgh, Edinburgh, UK.<br /><searchLink fieldCode="AU" term="%22Perosa+V%22">Perosa V</searchLink>; J. Philip Kistler Stroke Research Center, Department of Neurology, Harvard Medical School, Massachusetts General Hospital, Boston, Massachusetts, USA.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22John+Wiley+%26+Sons%2C+Ltd%22">John Wiley & Sons, Ltd </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101231978 <i>Publication Model: </i>Print <i>Cited Medium: </i>Internet <i>ISSN: </i>1552-5279 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2215525260%22">15525260 </searchLink><i>NLM ISO Abbreviation: </i>Alzheimers Dement <i>Subsets: </i>MEDLINE
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              Text: 2026 Mar
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