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Pharmacogenomic-Based GWAS Meta-Analyses Coupled with Genetic and Epigenetic Liability Testing Connects Facial and Emotional Recognition Systems to Spectrum Disorders, Schizophrenia, Depression, and Anxiety.

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Title: Pharmacogenomic-Based GWAS Meta-Analyses Coupled with Genetic and Epigenetic Liability Testing Connects Facial and Emotional Recognition Systems to Spectrum Disorders, Schizophrenia, Depression, and Anxiety.
Authors: Blum K; Department of Molecular Biology, Adelson School of Medicine, Ariel University, Ariel 40700, Israel.; Division of Addiction Research & Education, Center for Sports, Exercise, Psychiatry, Western University Health Sciences, Pomona, CA 91766-1854, USA.; The Kenneth Blum Behavioral & Neurogenetic Institute, Austin, TX 78701, USA.; Institute of Psychology, ELTE Eötvös Loránd University, H-1117 Budapest, Hungary., Lewandrowski APL; The Kenneth Blum Behavioral & Neurogenetic Institute, Austin, TX 78701, USA.; Department of Biological Sciences, Dornsife College of Letters, Arts and Sciences, 3616 Trousdale Pkwy, Los Angeles, CA 90089, USA., Sharafshah A; Cellular and Molecular Research Center, School of Medicine, Guilan University of Medical Sciences, Rasht 4144666949, Iran., Pinhasov A; Department of Molecular Biology, Adelson School of Medicine, Ariel University, Ariel 40700, Israel., Mohankumar K; The Kenneth Blum Behavioral & Neurogenetic Institute, Austin, TX 78701, USA., Gold MS; Department of Psychiatry, Washington University School of Medicine, St. Louis, MO 63110, USA., Fuehrlein B; Department of Psychiatry, Yale University, New Haven, CT, 06520, USA., Elman I; Cambridge Health Alliance, Harvard Medical School, Cambridge, MA, 02139, USA., Dennen C; Department of Family Medicine, Jefferson Health Northeast, Philadelphia, PA, 19145, USA., Thanos PK; Department of Pharmacology and Toxicology, State University of New York, SUNY, Buffalo, NY 14215, USA., Bowirrat A; Department of Molecular Biology, Adelson School of Medicine, Ariel University, Ariel 40700, Israel., Baron D; Division of Addiction Research & Education, Center for Sports, Exercise, Psychiatry, Western University Health Sciences, Pomona, CA 91766-1854, USA.; Department of Psychiatry, Stanford University School of Medicine, Palo Alto, CA 94305, USA., Modestino EJ; Brain & Behavior Laboratory, Department of Psychology, Curry College, Milton, MA 02186, USA., Jafari N; Department of Applied Clinical Psychology, The Chicago School of Professional Psychology, Los Angeles, CA 60601, USA., Zeine F; Department of Health Science, California State University at Long Beach, Long Beach, CA 90815, USA., Sunder K; Division of Addiction Research & Education, Center for Sports, Exercise, Psychiatry, Western University Health Sciences, Pomona, CA 91766-1854, USA.; Department of Psychiatry, University of California, UC Riverside School of Medicine, Riverside, CA 92521, USA., Makale MT; Department of Radiation Medicine and Applied Sciences, University of California San Diego, La Jolla, CA 92093, USA., Lorio MP; Advanced Orthopedics, Altamonte Springs, FL 32701, USA., Khalsa J; Medical Consequences of Drug Abuse and Infections Branch, National Institute on Drug Abuse, National Institutes of Health, Bethesda, MD 20852, USA., Schmidt SL; Programa de Pós-Graduação em Neurologia, Universidade Federal do Estado do Rio de Janeiro, Rio de Janeiro 20270-004, Brazil., Fiorelli RKA; Programa de Pós-Graduação em Neurologia, Universidade Federal do Estado do Rio de Janeiro, Rio de Janeiro 20270-004, Brazil., Weinstein A; Department of Behavioral Sciences, Ariel University, Ariel, 40700, Israel., Lindenau M; The Kenneth Blum Behavioral & Neurogenetic Institute, Austin, TX 78701, USA., Lewandrowski KU; Programa de Pós-Graduação em Neurologia, Universidade Federal do Estado do Rio de Janeiro, Rio de Janeiro 20270-004, Brazil.; Division of Personalized Medicine, Center for Advanced Spine Care of Southern Arizona, Tucson, AZ 85712, USA.; Department of Orthopaedics, Fundación Universitaria Sanitas, Bogotá 110131, Colombia.; Department of Orthopaedic Surgery, University of Arizona, School of Medicine, Tucson, AZ 85724, USA., Alves ÓL; Department of Neurosurgery, Hospital Lusíadas, Porto, Portugal., Mahajan S; The Kenneth Blum Behavioral & Neurogenetic Institute, Austin, TX 78701, USA., Mahajan Y; The Kenneth Blum Behavioral & Neurogenetic Institute, Austin, TX 78701, USA., Badgaiyan RD; Department of Psychiatry, Texas Tech University Health Sciences, School of Medicine, Midland, TX 79430, USA.
Source: Current pharmaceutical biotechnology [Curr Pharm Biotechnol] 2026 Mar 09. Date of Electronic Publication: 2026 Mar 09.
Publication Type: Journal Article; Meta-Analysis
Journal Info: Publisher: Bentham Science Publishers Country of Publication: Netherlands NLM ID: 100960530 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-4316 (Electronic) Linking ISSN: 13892010 NLM ISO Abbreviation: Curr Pharm Biotechnol Subsets: MEDLINE
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  Data: Pharmacogenomic-Based GWAS Meta-Analyses Coupled with Genetic and Epigenetic Liability Testing Connects Facial and Emotional Recognition Systems to Spectrum Disorders, Schizophrenia, Depression, and Anxiety.
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  Data: <searchLink fieldCode="AU" term="%22Blum+K%22">Blum K</searchLink>; Department of Molecular Biology, Adelson School of Medicine, Ariel University, Ariel 40700, Israel.; Division of Addiction Research & Education, Center for Sports, Exercise, Psychiatry, Western University Health Sciences, Pomona, CA 91766-1854, USA.; The Kenneth Blum Behavioral & Neurogenetic Institute, Austin, TX 78701, USA.; Institute of Psychology, ELTE Eötvös Loránd University, H-1117 Budapest, Hungary.<br /><searchLink fieldCode="AU" term="%22Lewandrowski+APL%22">Lewandrowski APL</searchLink>; The Kenneth Blum Behavioral & Neurogenetic Institute, Austin, TX 78701, USA.; Department of Biological Sciences, Dornsife College of Letters, Arts and Sciences, 3616 Trousdale Pkwy, Los Angeles, CA 90089, USA.<br /><searchLink fieldCode="AU" term="%22Sharafshah+A%22">Sharafshah A</searchLink>; Cellular and Molecular Research Center, School of Medicine, Guilan University of Medical Sciences, Rasht 4144666949, Iran.<br /><searchLink fieldCode="AU" term="%22Pinhasov+A%22">Pinhasov A</searchLink>; Department of Molecular Biology, Adelson School of Medicine, Ariel University, Ariel 40700, Israel.<br /><searchLink fieldCode="AU" term="%22Mohankumar+K%22">Mohankumar K</searchLink>; The Kenneth Blum Behavioral & Neurogenetic Institute, Austin, TX 78701, USA.<br /><searchLink fieldCode="AU" term="%22Gold+MS%22">Gold MS</searchLink>; Department of Psychiatry, Washington University School of Medicine, St. Louis, MO 63110, USA.<br /><searchLink fieldCode="AU" term="%22Fuehrlein+B%22">Fuehrlein B</searchLink>; Department of Psychiatry, Yale University, New Haven, CT, 06520, USA.<br /><searchLink fieldCode="AU" term="%22Elman+I%22">Elman I</searchLink>; Cambridge Health Alliance, Harvard Medical School, Cambridge, MA, 02139, USA.<br /><searchLink fieldCode="AU" term="%22Dennen+C%22">Dennen C</searchLink>; Department of Family Medicine, Jefferson Health Northeast, Philadelphia, PA, 19145, USA.<br /><searchLink fieldCode="AU" term="%22Thanos+PK%22">Thanos PK</searchLink>; Department of Pharmacology and Toxicology, State University of New York, SUNY, Buffalo, NY 14215, USA.<br /><searchLink fieldCode="AU" term="%22Bowirrat+A%22">Bowirrat A</searchLink>; 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Division of Addiction Research & Education, Center for Sports, Exercise, Psychiatry, Western University Health Sciences, Pomona, CA 91766-1854, USA.; Department of Psychiatry, University of California, UC Riverside School of Medicine, Riverside, CA 92521, USA.<br /><searchLink fieldCode="AU" term="%22Makale+MT%22">Makale MT</searchLink>; Department of Radiation Medicine and Applied Sciences, University of California San Diego, La Jolla, CA 92093, USA.<br /><searchLink fieldCode="AU" term="%22Lorio+MP%22">Lorio MP</searchLink>; Advanced Orthopedics, Altamonte Springs, FL 32701, USA.<br /><searchLink fieldCode="AU" term="%22Khalsa+J%22">Khalsa J</searchLink>; Medical Consequences of Drug Abuse and Infections Branch, National Institute on Drug Abuse, National Institutes of Health, Bethesda, MD 20852, USA.<br /><searchLink fieldCode="AU" term="%22Schmidt+SL%22">Schmidt SL</searchLink>; Programa de Pós-Graduação em Neurologia, Universidade Federal do Estado do Rio de Janeiro, Rio de Janeiro 20270-004, Brazil.<br /><searchLink fieldCode="AU" term="%22Fiorelli+RKA%22">Fiorelli RKA</searchLink>; Programa de Pós-Graduação em Neurologia, Universidade Federal do Estado do Rio de Janeiro, Rio de Janeiro 20270-004, Brazil.<br /><searchLink fieldCode="AU" term="%22Weinstein+A%22">Weinstein A</searchLink>; Department of Behavioral Sciences, Ariel University, Ariel, 40700, Israel.<br /><searchLink fieldCode="AU" term="%22Lindenau+M%22">Lindenau M</searchLink>; The Kenneth Blum Behavioral & Neurogenetic Institute, Austin, TX 78701, USA.<br /><searchLink fieldCode="AU" term="%22Lewandrowski+KU%22">Lewandrowski KU</searchLink>; Programa de Pós-Graduação em Neurologia, Universidade Federal do Estado do Rio de Janeiro, Rio de Janeiro 20270-004, Brazil.; Division of Personalized Medicine, Center for Advanced Spine Care of Southern Arizona, Tucson, AZ 85712, USA.; Department of Orthopaedics, Fundación Universitaria Sanitas, Bogotá 110131, Colombia.; Department of Orthopaedic Surgery, University of Arizona, School of Medicine, Tucson, AZ 85724, USA.<br /><searchLink fieldCode="AU" term="%22Alves+ÓL%22">Alves ÓL</searchLink>; Department of Neurosurgery, Hospital Lusíadas, Porto, Portugal.<br /><searchLink fieldCode="AU" term="%22Mahajan+S%22">Mahajan S</searchLink>; The Kenneth Blum Behavioral & Neurogenetic Institute, Austin, TX 78701, USA.<br /><searchLink fieldCode="AU" term="%22Mahajan+Y%22">Mahajan Y</searchLink>; The Kenneth Blum Behavioral & Neurogenetic Institute, Austin, TX 78701, USA.<br /><searchLink fieldCode="AU" term="%22Badgaiyan+RD%22">Badgaiyan RD</searchLink>; Department of Psychiatry, Texas Tech University Health Sciences, School of Medicine, Midland, TX 79430, USA.
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