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Hyaluronic acid-based dissolving microneedles regulate antigen release and route-dependent immunogenicity of adenovirus-based vaccines.

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Title: Hyaluronic acid-based dissolving microneedles regulate antigen release and route-dependent immunogenicity of adenovirus-based vaccines.
Authors: Min HS; Department of Biotechnology, Yonsei University, 50 Yonsei-ro, Seoul, 03722, Republic of Korea., Jang E; Graduate School of Pharmaceutical Sciences, Ewha Womans University, 52 Ewhayeodae-gil, Seoul, 03760, Republic of Korea., Lee Y; Department of Integrative Biotechnology, Yonsei University 85, Songdogwahak-ro, Inchon, 21983, Republic of Korea., Cho SM; Department of Integrative Biotechnology, Yonsei University 85, Songdogwahak-ro, Inchon, 21983, Republic of Korea., Nam J; Department of Biotechnology, Yonsei University, 50 Yonsei-ro, Seoul, 03722, Republic of Korea., Lee S; Graduate School of Pharmaceutical Sciences, Ewha Womans University, 52 Ewhayeodae-gil, Seoul, 03760, Republic of Korea., Kim Y; Department of Biotechnology, Yonsei University, 50 Yonsei-ro, Seoul, 03722, Republic of Korea., Kim P; Juvic Inc., 208 Ho, 272, Digital-ro, Guro-gu, Seoul, 08389, Republic of Korea., Chang J; Graduate School of Pharmaceutical Sciences, Ewha Womans University, 52 Ewhayeodae-gil, Seoul, 03760, Republic of Korea. Electronic address: tcell@ewha.ac.kr., Jung H; Department of Biotechnology, Yonsei University, 50 Yonsei-ro, Seoul, 03722, Republic of Korea; Juvic Inc., 208 Ho, 272, Digital-ro, Guro-gu, Seoul, 08389, Republic of Korea. Electronic address: hijung@yonsei.ac.kr.
Source: Carbohydrate polymers [Carbohydr Polym] 2026 May 15; Vol. 380, pp. 125118. Date of Electronic Publication: 2026 Feb 18.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Applied Science Publishers Country of Publication: England NLM ID: 8307156 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-1344 (Electronic) Linking ISSN: 01448617 NLM ISO Abbreviation: Carbohydr Polym Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1879-1344
DOI:10.1016/j.carbpol.2026.125118