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Human 3D Cardiac Microtissue Model to Investigate Aldosterone-Induced Fibrosis and Electrical Dysfunction.

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Title: Human 3D Cardiac Microtissue Model to Investigate Aldosterone-Induced Fibrosis and Electrical Dysfunction.
Authors: Burrello J; Division of Internal Medicine and Hypertension Unit, Department of Medical Sciences (J.B., F.B., P.M., S.M.), University of Torino, Italy., Senesi G; Institute for Translational Research (IRT), Faculty of Biomedical Sciences, Università Svizzera italiana (USI) and Ente Ospedaliero Cantonale (EOC), Bellinzona, Switzerland (G.S., C.A., L.B.).; Cardiovascular Theranostics Group, Istituto Cardiocentro Ticino, Ente Ospedaliero Cantonale (EOC), Bellinzona, Switzerland (G.S., C.A., L.B.)., Altomare C; Institute for Translational Research (IRT), Faculty of Biomedical Sciences, Università Svizzera italiana (USI) and Ente Ospedaliero Cantonale (EOC), Bellinzona, Switzerland (G.S., C.A., L.B.).; Cardiovascular Theranostics Group, Istituto Cardiocentro Ticino, Ente Ospedaliero Cantonale (EOC), Bellinzona, Switzerland (G.S., C.A., L.B.)., Buffolo F; Division of Internal Medicine and Hypertension Unit, Department of Medical Sciences (J.B., F.B., P.M., S.M.), University of Torino, Italy., D'Ascenzo F; Division of Cardiology, Department of Medical Sciences (F.D.A.), University of Torino, Italy., Barile L; Institute for Translational Research (IRT), Faculty of Biomedical Sciences, Università Svizzera italiana (USI) and Ente Ospedaliero Cantonale (EOC), Bellinzona, Switzerland (G.S., C.A., L.B.).; Cardiovascular Theranostics Group, Istituto Cardiocentro Ticino, Ente Ospedaliero Cantonale (EOC), Bellinzona, Switzerland (G.S., C.A., L.B.)., Mulatero P; Division of Internal Medicine and Hypertension Unit, Department of Medical Sciences (J.B., F.B., P.M., S.M.), University of Torino, Italy., Balbi C; Center for Molecular Cardiology, University of Zurich, Schlieren, Switzerland (C.B.).; Department of Internal Medicine, Cantonal Hospital of Baden, Switzerland (C.B.)., Monticone S; Division of Internal Medicine and Hypertension Unit, Department of Medical Sciences (J.B., F.B., P.M., S.M.), University of Torino, Italy.
Source: Hypertension (Dallas, Tex. : 1979) [Hypertension] 2026 May; Vol. 83 (5), pp. e25686. Date of Electronic Publication: 2026 Mar 16.
Publication Type: Journal Article
Journal Info: Publisher: Lippincott, Williams & Wilkins Country of Publication: United States NLM ID: 7906255 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1524-4563 (Electronic) Linking ISSN: 0194911X NLM ISO Abbreviation: Hypertension Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Burrello+J%22">Burrello J</searchLink>; Division of Internal Medicine and Hypertension Unit, Department of Medical Sciences (J.B., F.B., P.M., S.M.), University of Torino, Italy.<br /><searchLink fieldCode="AU" term="%22Senesi+G%22">Senesi G</searchLink>; Institute for Translational Research (IRT), Faculty of Biomedical Sciences, Università Svizzera italiana (USI) and Ente Ospedaliero Cantonale (EOC), Bellinzona, Switzerland (G.S., C.A., L.B.).; Cardiovascular Theranostics Group, Istituto Cardiocentro Ticino, Ente Ospedaliero Cantonale (EOC), Bellinzona, Switzerland (G.S., C.A., L.B.).<br /><searchLink fieldCode="AU" term="%22Altomare+C%22">Altomare C</searchLink>; Institute for Translational Research (IRT), Faculty of Biomedical Sciences, Università Svizzera italiana (USI) and Ente Ospedaliero Cantonale (EOC), Bellinzona, Switzerland (G.S., C.A., L.B.).; Cardiovascular Theranostics Group, Istituto Cardiocentro Ticino, Ente Ospedaliero Cantonale (EOC), Bellinzona, Switzerland (G.S., C.A., L.B.).<br /><searchLink fieldCode="AU" term="%22Buffolo+F%22">Buffolo F</searchLink>; Division of Internal Medicine and Hypertension Unit, Department of Medical Sciences (J.B., F.B., P.M., S.M.), University of Torino, Italy.<br /><searchLink fieldCode="AU" term="%22D'Ascenzo+F%22">D'Ascenzo F</searchLink>; Division of Cardiology, Department of Medical Sciences (F.D.A.), University of Torino, Italy.<br /><searchLink fieldCode="AU" term="%22Barile+L%22">Barile L</searchLink>; Institute for Translational Research (IRT), Faculty of Biomedical Sciences, Università Svizzera italiana (USI) and Ente Ospedaliero Cantonale (EOC), Bellinzona, Switzerland (G.S., C.A., L.B.).; Cardiovascular Theranostics Group, Istituto Cardiocentro Ticino, Ente Ospedaliero Cantonale (EOC), Bellinzona, Switzerland (G.S., C.A., L.B.).<br /><searchLink fieldCode="AU" term="%22Mulatero+P%22">Mulatero P</searchLink>; Division of Internal Medicine and Hypertension Unit, Department of Medical Sciences (J.B., F.B., P.M., S.M.), University of Torino, Italy.<br /><searchLink fieldCode="AU" term="%22Balbi+C%22">Balbi C</searchLink>; Center for Molecular Cardiology, University of Zurich, Schlieren, Switzerland (C.B.).; Department of Internal Medicine, Cantonal Hospital of Baden, Switzerland (C.B.).<br /><searchLink fieldCode="AU" term="%22Monticone+S%22">Monticone S</searchLink>; Division of Internal Medicine and Hypertension Unit, Department of Medical Sciences (J.B., F.B., P.M., S.M.), University of Torino, Italy.
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  Data: <searchLink fieldCode="JN" term="%227906255%22">Hypertension (Dallas, Tex. : 1979)</searchLink> [Hypertension] 2026 May; Vol. 83 (5), pp. e25686. <i>Date of Electronic Publication: </i>2026 Mar 16.
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        Value: 10.1161/HYPERTENSIONAHA.125.25686
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              Text: 2026 May
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