Algorithm-Based Care for Treating Chronic Pancreatitis: A Nationwide Stepped-Wedge Cluster Randomized Controlled Trial.

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Title: Algorithm-Based Care for Treating Chronic Pancreatitis: A Nationwide Stepped-Wedge Cluster Randomized Controlled Trial.
Authors: de Rijk FEM; Department of Gastroenterology and Hepatology, Erasmus University Medical Center, Rotterdam, the Netherlands.; Department of Research and Development, St. Antonius Hospital, Nieuwegein, the Netherlands., Thierens NDE; Department of Research and Development, St. Antonius Hospital, Nieuwegein, the Netherlands.; Department of Gastroenterology and Hepatology, Radboud University Medical Center, Nijmegen, the Netherlands., van Veldhuisen CL; Department of Research and Development, St. Antonius Hospital, Nieuwegein, the Netherlands.; Department of Surgery, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands.; Amsterdam Gastroenterology Endocrinology Metabolism, Amsterdam, the Netherlands., Aman BA; Department of Research and Development, St. Antonius Hospital, Nieuwegein, the Netherlands., Anten MPGF; Department of Gastroenterology and Hepatology, Sint Franciscus Hospital, Rotterdam, the Netherlands., Bhalla A; Department of Gastroenterology and Hepatology, Haga Hospital, The Hague, the Netherlands., Bos PR; Department of Gastroenterology and Hepatology, Hospital Gelderse Vallei, Ede, the Netherlands., Brink MA; Department of Gastroenterology and Hepatology, Meander Medical Center, Amersfoort, the Netherlands., Curvers WL; Department of Gastroenterology and Hepatology, Catharina Hospital, Eindhoven, the Netherlands., van Eijck BC; Department of Gastroenterology and Hepatology, Spaarne Gasthuis, Hoofddorp, the Netherlands., van Geenen EJM; Department of Gastroenterology and Hepatology, Radboud University Medical Center, Nijmegen, the Netherlands., Hadithi M; Department of Gastroenterology and Hepatology, Maasstad Hospital, Rotterdam, the Netherlands., Inderson A; Department of Gastroenterology and Hepatology, Leiden University Medical Center, Leiden, the Netherlands., Kager LM; Department of Gastroenterology and Hepatology, Noordwest Ziekenhuisgroep, Alkmaar, the Netherlands., Keulemans YL; Department of Gastroenterology and Hepatology, Zuyderland Medical Center, Sittard, the Netherlands., Koehestanie P; Department of Gastroenterology and Hepatology, Bravis Hospital, Roosendaal, the Netherlands., Kuiken SD; Department of Gastroenterology and Hepatology, OLVG, Amsterdam, the Netherlands., Poen AC; Department of Gastroenterology and Hepatology, Isala, Zwolle, the Netherlands., Quispel R; Department of Gastroenterology and Hepatology, Reinier de Graaf Gasthuis, Delft, the Netherlands., Römkens TEH; Department of Gastroenterology and Hepatology, Jeroen Bosch Hospital, 's-Hertogenbosch, the Netherlands., Nicolaas JS; Department of Gastroenterology and Hepatology, Amphia Hospital, Breda, the Netherlands., van der Schaar PJ; Department of Gastroenterology and Hepatology, St. Antonius Hospital, Nieuwegein, the Netherlands., Straathof JWA; Department of Gastroenterology and Hepatology, Maxima Medical Center, Veldhoven, the Netherlands., Tan ACITL; Department of Gastroenterology and Hepatology, Canisius Wilhelmina Hospital, Nijmegen, the Netherlands., Thijs WJ; Department of Gastroenterology and Hepatology, Martini Hospital, Groningen, the Netherlands., Tielemans MM; Department of Gastroenterology and Hepatology, Bravis Hospital, Roosendaal, the Netherlands., Venneman NG; Department of Gastroenterology and Hepatology, Medical Spectrum Twente, Enschede, the Netherlands., Vleggaar FP; Department of Gastroenterology and Hepatology, University Medical Center Utrecht, Utrecht, the Netherlands., Voermans RP; Department of Gastroenterology and Hepatology, Amsterdam, University Medical Center, University of AmsterdamAmsterdam, the Netherlands., van Wanrooij RLJ; Amsterdam Gastroenterology Endocrinology Metabolism, Amsterdam, the Netherlands.; Department of Gastroenterology and Hepatology, Amsterdam UMC, Vrije Universiteit, Amsterdam, the Netherlands., Verlaan T; Department of Gastroenterology and Hepatology, Hospital Gelderse Vallei, Ede, the Netherlands., Zoutendijk R; Department of Gastroenterology and Hepatology, St. Antonius Hospital, Nieuwegein, the Netherlands., Besselink MG; Department of Surgery, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands.; Amsterdam Gastroenterology Endocrinology Metabolism, Amsterdam, the Netherlands., Drenth JPH; Department of Gastroenterology and Hepatology, Amsterdam, University Medical Center, University of AmsterdamAmsterdam, the Netherlands., van Hooft JE; Department of Gastroenterology and Hepatology, Leiden University Medical Center, Leiden, the Netherlands., van Santvoort HC; Department of Surgery, St. Antonius Hospital, Nieuwegein, the Netherlands.; Department of Surgery, University Medical Center Utrecht, Utrecht, the Netherlands., van Werkhoven CH; Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands., de Jonge PJF; Department of Gastroenterology and Hepatology, Erasmus University Medical Center, Rotterdam, the Netherlands., Bruno MJ; Department of Gastroenterology and Hepatology, Erasmus University Medical Center, Rotterdam, the Netherlands., Verdonk RC; Department of Gastroenterology and Hepatology, St. Antonius Hospital, Nieuwegein, the Netherlands.
Corporate Authors: Dutch Pancreatitis Study Group
Source: The American journal of gastroenterology [Am J Gastroenterol] 2026 Mar 17. Date of Electronic Publication: 2026 Mar 17.
Publication Type: Journal Article
Journal Info: Publisher: Wolters Kluwer Health Country of Publication: United States NLM ID: 0421030 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1572-0241 (Electronic) Linking ISSN: 00029270 NLM ISO Abbreviation: Am J Gastroenterol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Algorithm-Based Care for Treating Chronic Pancreatitis: A Nationwide Stepped-Wedge Cluster Randomized Controlled Trial.
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  Data: <searchLink fieldCode="AU" term="%22de+Rijk+FEM%22">de Rijk FEM</searchLink>; Department of Gastroenterology and Hepatology, Erasmus University Medical Center, Rotterdam, the Netherlands.; Department of Research and Development, St. Antonius Hospital, Nieuwegein, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Thierens+NDE%22">Thierens NDE</searchLink>; Department of Research and Development, St. Antonius Hospital, Nieuwegein, the Netherlands.; Department of Gastroenterology and Hepatology, Radboud University Medical Center, Nijmegen, the Netherlands.<br /><searchLink fieldCode="AU" term="%22van+Veldhuisen+CL%22">van Veldhuisen CL</searchLink>; Department of Research and Development, St. Antonius Hospital, Nieuwegein, the Netherlands.; Department of Surgery, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands.; Amsterdam Gastroenterology Endocrinology Metabolism, Amsterdam, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Aman+BA%22">Aman BA</searchLink>; Department of Research and Development, St. Antonius Hospital, Nieuwegein, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Anten+MPGF%22">Anten MPGF</searchLink>; Department of Gastroenterology and Hepatology, Sint Franciscus Hospital, Rotterdam, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Bhalla+A%22">Bhalla A</searchLink>; Department of Gastroenterology and Hepatology, Haga Hospital, The Hague, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Bos+PR%22">Bos PR</searchLink>; Department of Gastroenterology and Hepatology, Hospital Gelderse Vallei, Ede, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Brink+MA%22">Brink MA</searchLink>; Department of Gastroenterology and Hepatology, Meander Medical Center, Amersfoort, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Curvers+WL%22">Curvers WL</searchLink>; Department of Gastroenterology and Hepatology, Catharina Hospital, Eindhoven, the Netherlands.<br /><searchLink fieldCode="AU" term="%22van+Eijck+BC%22">van Eijck BC</searchLink>; Department of Gastroenterology and Hepatology, Spaarne Gasthuis, Hoofddorp, the Netherlands.<br /><searchLink fieldCode="AU" term="%22van+Geenen+EJM%22">van Geenen EJM</searchLink>; Department of Gastroenterology and Hepatology, Radboud University Medical Center, Nijmegen, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Hadithi+M%22">Hadithi M</searchLink>; Department of Gastroenterology and Hepatology, Maasstad Hospital, Rotterdam, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Inderson+A%22">Inderson A</searchLink>; Department of Gastroenterology and Hepatology, Leiden University Medical Center, Leiden, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Kager+LM%22">Kager LM</searchLink>; Department of Gastroenterology and Hepatology, Noordwest Ziekenhuisgroep, Alkmaar, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Keulemans+YL%22">Keulemans YL</searchLink>; Department of Gastroenterology and Hepatology, Zuyderland Medical Center, Sittard, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Koehestanie+P%22">Koehestanie P</searchLink>; Department of Gastroenterology and Hepatology, Bravis Hospital, Roosendaal, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Kuiken+SD%22">Kuiken SD</searchLink>; Department of Gastroenterology and Hepatology, OLVG, Amsterdam, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Poen+AC%22">Poen AC</searchLink>; Department of Gastroenterology and Hepatology, Isala, Zwolle, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Quispel+R%22">Quispel R</searchLink>; Department of Gastroenterology and Hepatology, Reinier de Graaf Gasthuis, Delft, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Römkens+TEH%22">Römkens TEH</searchLink>; Department of Gastroenterology and Hepatology, Jeroen Bosch Hospital, 's-Hertogenbosch, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Nicolaas+JS%22">Nicolaas JS</searchLink>; Department of Gastroenterology and Hepatology, Amphia Hospital, Breda, the Netherlands.<br /><searchLink fieldCode="AU" term="%22van+der+Schaar+PJ%22">van der Schaar PJ</searchLink>; Department of Gastroenterology and Hepatology, St. Antonius Hospital, Nieuwegein, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Straathof+JWA%22">Straathof JWA</searchLink>; Department of Gastroenterology and Hepatology, Maxima Medical Center, Veldhoven, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Tan+ACITL%22">Tan ACITL</searchLink>; Department of Gastroenterology and Hepatology, Canisius Wilhelmina Hospital, Nijmegen, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Thijs+WJ%22">Thijs WJ</searchLink>; Department of Gastroenterology and Hepatology, Martini Hospital, Groningen, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Tielemans+MM%22">Tielemans MM</searchLink>; Department of Gastroenterology and Hepatology, Bravis Hospital, Roosendaal, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Venneman+NG%22">Venneman NG</searchLink>; Department of Gastroenterology and Hepatology, Medical Spectrum Twente, Enschede, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Vleggaar+FP%22">Vleggaar FP</searchLink>; Department of Gastroenterology and Hepatology, University Medical Center Utrecht, Utrecht, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Voermans+RP%22">Voermans RP</searchLink>; Department of Gastroenterology and Hepatology, Amsterdam, University Medical Center, University of AmsterdamAmsterdam, the Netherlands.<br /><searchLink fieldCode="AU" term="%22van+Wanrooij+RLJ%22">van Wanrooij RLJ</searchLink>; Amsterdam Gastroenterology Endocrinology Metabolism, Amsterdam, the Netherlands.; Department of Gastroenterology and Hepatology, Amsterdam UMC, Vrije Universiteit, Amsterdam, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Verlaan+T%22">Verlaan T</searchLink>; Department of Gastroenterology and Hepatology, Hospital Gelderse Vallei, Ede, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Zoutendijk+R%22">Zoutendijk R</searchLink>; Department of Gastroenterology and Hepatology, St. Antonius Hospital, Nieuwegein, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Besselink+MG%22">Besselink MG</searchLink>; Department of Surgery, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands.; Amsterdam Gastroenterology Endocrinology Metabolism, Amsterdam, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Drenth+JPH%22">Drenth JPH</searchLink>; Department of Gastroenterology and Hepatology, Amsterdam, University Medical Center, University of AmsterdamAmsterdam, the Netherlands.<br /><searchLink fieldCode="AU" term="%22van+Hooft+JE%22">van Hooft JE</searchLink>; Department of Gastroenterology and Hepatology, Leiden University Medical Center, Leiden, the Netherlands.<br /><searchLink fieldCode="AU" term="%22van+Santvoort+HC%22">van Santvoort HC</searchLink>; Department of Surgery, St. Antonius Hospital, Nieuwegein, the Netherlands.; Department of Surgery, University Medical Center Utrecht, Utrecht, the Netherlands.<br /><searchLink fieldCode="AU" term="%22van+Werkhoven+CH%22">van Werkhoven CH</searchLink>; Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands.<br /><searchLink fieldCode="AU" term="%22de+Jonge+PJF%22">de Jonge PJF</searchLink>; Department of Gastroenterology and Hepatology, Erasmus University Medical Center, Rotterdam, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Bruno+MJ%22">Bruno MJ</searchLink>; Department of Gastroenterology and Hepatology, Erasmus University Medical Center, Rotterdam, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Verdonk+RC%22">Verdonk RC</searchLink>; Department of Gastroenterology and Hepatology, St. Antonius Hospital, Nieuwegein, the Netherlands.
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