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LncRNA SNHG5 promotes macrophage lipid accumulation and aggravates atherosclerosis by targeting the miR-216a-5p/HDAC3/ABCA1 axis.

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Title: LncRNA SNHG5 promotes macrophage lipid accumulation and aggravates atherosclerosis by targeting the miR-216a-5p/HDAC3/ABCA1 axis.
Authors: Liu X; College of Nursing, Anhui University of Chinese Medicine, Hefei, 230012, Anhui, PR China; Key Laboratory of Geriatric Nursing and Health, Anhui University of Chinese Medicine, Hefei, 230012, Anhui, PR China., Wang HH; College of Nursing, Anhui University of Chinese Medicine, Hefei, 230012, Anhui, PR China; Key Laboratory of Geriatric Nursing and Health, Anhui University of Chinese Medicine, Hefei, 230012, Anhui, PR China., Lan XY; College of Nursing, Anhui University of Chinese Medicine, Hefei, 230012, Anhui, PR China., Sun SY; First Clinical Medical College, Anhui University of Chinese Medicine, Hefei, 230022, Anhui, PR China., Xu XD; Department of Pathology, The First Affiliated Hospital of Anhui Medical University, Hefei, 230022, Anhui, PR China., Hui L; College of Nursing, Anhui University of Chinese Medicine, Hefei, 230012, Anhui, PR China., Xu GH; College of Nursing, Anhui University of Chinese Medicine, Hefei, 230012, Anhui, PR China., Zhu L; College of Pharmacy, Anhui University of Chinese Medicine, Hefei, 230012, Anhui, PR China; Institute for Pharmacodynamics and Safety Evaluation of Chinese Medicine, Anhui Academy of Traditional Chinese Medicine, Hefei, 230012, Anhui, PR China; Anhui Province Key Laboratory of Traditional Chinese Medicine Decoction Pieces of New Manufacturing Technology, Hefei, 230012, Anhui, PR China. Electronic address: 657922023@qq.com., Ren K; College of Nursing, Anhui University of Chinese Medicine, Hefei, 230012, Anhui, PR China; Key Laboratory of Geriatric Nursing and Health, Anhui University of Chinese Medicine, Hefei, 230012, Anhui, PR China. Electronic address: kr198908@163.com.
Source: Biochimica et biophysica acta. Molecular and cell biology of lipids [Biochim Biophys Acta Mol Cell Biol Lipids] 2026 May; Vol. 1871 (4), pp. 159738. Date of Electronic Publication: 2026 Mar 16.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 101731727 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-2618 (Electronic) Linking ISSN: 13881981 NLM ISO Abbreviation: Biochim Biophys Acta Mol Cell Biol Lipids Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: LncRNA SNHG5 promotes macrophage lipid accumulation and aggravates atherosclerosis by targeting the miR-216a-5p/HDAC3/ABCA1 axis.
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  Data: <searchLink fieldCode="AU" term="%22Liu+X%22">Liu X</searchLink>; College of Nursing, Anhui University of Chinese Medicine, Hefei, 230012, Anhui, PR China; Key Laboratory of Geriatric Nursing and Health, Anhui University of Chinese Medicine, Hefei, 230012, Anhui, PR China.<br /><searchLink fieldCode="AU" term="%22Wang+HH%22">Wang HH</searchLink>; College of Nursing, Anhui University of Chinese Medicine, Hefei, 230012, Anhui, PR China; Key Laboratory of Geriatric Nursing and Health, Anhui University of Chinese Medicine, Hefei, 230012, Anhui, PR China.<br /><searchLink fieldCode="AU" term="%22Lan+XY%22">Lan XY</searchLink>; College of Nursing, Anhui University of Chinese Medicine, Hefei, 230012, Anhui, PR China.<br /><searchLink fieldCode="AU" term="%22Sun+SY%22">Sun SY</searchLink>; First Clinical Medical College, Anhui University of Chinese Medicine, Hefei, 230022, Anhui, PR China.<br /><searchLink fieldCode="AU" term="%22Xu+XD%22">Xu XD</searchLink>; Department of Pathology, The First Affiliated Hospital of Anhui Medical University, Hefei, 230022, Anhui, PR China.<br /><searchLink fieldCode="AU" term="%22Hui+L%22">Hui L</searchLink>; College of Nursing, Anhui University of Chinese Medicine, Hefei, 230012, Anhui, PR China.<br /><searchLink fieldCode="AU" term="%22Xu+GH%22">Xu GH</searchLink>; College of Nursing, Anhui University of Chinese Medicine, Hefei, 230012, Anhui, PR China.<br /><searchLink fieldCode="AU" term="%22Zhu+L%22">Zhu L</searchLink>; College of Pharmacy, Anhui University of Chinese Medicine, Hefei, 230012, Anhui, PR China; Institute for Pharmacodynamics and Safety Evaluation of Chinese Medicine, Anhui Academy of Traditional Chinese Medicine, Hefei, 230012, Anhui, PR China; Anhui Province Key Laboratory of Traditional Chinese Medicine Decoction Pieces of New Manufacturing Technology, Hefei, 230012, Anhui, PR China. Electronic address: 657922023@qq.com.<br /><searchLink fieldCode="AU" term="%22Ren+K%22">Ren K</searchLink>; College of Nursing, Anhui University of Chinese Medicine, Hefei, 230012, Anhui, PR China; Key Laboratory of Geriatric Nursing and Health, Anhui University of Chinese Medicine, Hefei, 230012, Anhui, PR China. Electronic address: kr198908@163.com.
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  Data: <searchLink fieldCode="JN" term="%22101731727%22">Biochimica et biophysica acta. Molecular and cell biology of lipids</searchLink> [Biochim Biophys Acta Mol Cell Biol Lipids] 2026 May; Vol. 1871 (4), pp. 159738. <i>Date of Electronic Publication: </i>2026 Mar 16.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier%22">Elsevier </searchLink><i>Country of Publication: </i>Netherlands <i>NLM ID: </i>101731727 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1879-2618 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2213881981%22">13881981 </searchLink><i>NLM ISO Abbreviation: </i>Biochim Biophys Acta Mol Cell Biol Lipids <i>Subsets: </i>MEDLINE
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        Value: 10.1016/j.bbalip.2026.159738
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      – Code: eng
        Text: English
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        StartPage: 159738
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      – TitleFull: LncRNA SNHG5 promotes macrophage lipid accumulation and aggravates atherosclerosis by targeting the miR-216a-5p/HDAC3/ABCA1 axis.
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            – D: 01
              M: 05
              Text: 2026 May
              Type: published
              Y: 2026
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