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Genomic Features and Response to Poly(ADP-ribose) Polymerase Inhibition in Metastatic Castration-Resistant Prostate Cancer.

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Title: Genomic Features and Response to Poly(ADP-ribose) Polymerase Inhibition in Metastatic Castration-Resistant Prostate Cancer.
Authors: Chang JCW; Genitourinary Oncology Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY., Nandakumar S; Department of Epidemiology & Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY., Stopsack KH; Genitourinary Oncology Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY.; Department of Epidemiological Methods and Etiologic Research, Leibniz Institute for Prevention Research and Epidemiology-BIPS and Faculty of Human and Health Sciences, University of Bremen, Bremen, Germany., Fong C; Department of Epidemiology & Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY., Pichotta K; Department of Epidemiology & Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY., Jee J; Department of Epidemiology & Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY., Woo HJ; Marie-Josée and Henry R. Kravis Center for Molecular Oncology, Memorial Sloan Kettering Cancer Center, New York, NY., Donoghue MTA; Marie-Josée and Henry R. Kravis Center for Molecular Oncology, Memorial Sloan Kettering Cancer Center, New York, NY., Vasselman S; Genitourinary Oncology Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY., Barnett E; Genitourinary Oncology Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY., Autio KA; Genitourinary Oncology Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY., Danila D; Genitourinary Oncology Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY., McHugh D; Genitourinary Oncology Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY., Morris M; Genitourinary Oncology Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY., Rathkopf D; Genitourinary Oncology Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY., Scher H; Genitourinary Oncology Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY., Slovin S; Genitourinary Oncology Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY., Kantoff P; Genitourinary Oncology Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY.; Convergent Therapeutics, Cambridge, MA., Gopalan A; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY., Solit DB; Genitourinary Oncology Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY.; Marie-Josée and Henry R. Kravis Center for Molecular Oncology, Memorial Sloan Kettering Cancer Center, New York, NY.; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY., Wibmer A; Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY., Schultz N; Department of Epidemiology & Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY.; Marie-Josée and Henry R. Kravis Center for Molecular Oncology, Memorial Sloan Kettering Cancer Center, New York, NY., Abida W; Genitourinary Oncology Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY.
Source: JCO precision oncology [JCO Precis Oncol] 2026 Mar; Vol. 10 (3), pp. e2500934. Date of Electronic Publication: 2026 Mar 18.
Publication Type: Journal Article; Observational Study
Journal Info: Publisher: American Society of Clinical Oncology Country of Publication: United States NLM ID: 101705370 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2473-4284 (Electronic) Linking ISSN: 24734284 NLM ISO Abbreviation: JCO Precis Oncol Subsets: MEDLINE
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  Data: Genomic Features and Response to Poly(ADP-ribose) Polymerase Inhibition in Metastatic Castration-Resistant Prostate Cancer.
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  Data: <searchLink fieldCode="AU" term="%22Chang+JCW%22">Chang JCW</searchLink>; Genitourinary Oncology Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY.<br /><searchLink fieldCode="AU" term="%22Nandakumar+S%22">Nandakumar S</searchLink>; Department of Epidemiology & Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY.<br /><searchLink fieldCode="AU" term="%22Stopsack+KH%22">Stopsack KH</searchLink>; Genitourinary Oncology Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY.; Department of Epidemiological Methods and Etiologic Research, Leibniz Institute for Prevention Research and Epidemiology-BIPS and Faculty of Human and Health Sciences, University of Bremen, Bremen, Germany.<br /><searchLink fieldCode="AU" term="%22Fong+C%22">Fong C</searchLink>; Department of Epidemiology & Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY.<br /><searchLink fieldCode="AU" term="%22Pichotta+K%22">Pichotta K</searchLink>; Department of Epidemiology & Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY.<br /><searchLink fieldCode="AU" term="%22Jee+J%22">Jee J</searchLink>; Department of Epidemiology & Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY.<br /><searchLink fieldCode="AU" term="%22Woo+HJ%22">Woo HJ</searchLink>; Marie-Josée and Henry R. Kravis Center for Molecular Oncology, Memorial Sloan Kettering Cancer Center, New York, NY.<br /><searchLink fieldCode="AU" term="%22Donoghue+MTA%22">Donoghue MTA</searchLink>; Marie-Josée and Henry R. Kravis Center for Molecular Oncology, Memorial Sloan Kettering Cancer Center, New York, NY.<br /><searchLink fieldCode="AU" term="%22Vasselman+S%22">Vasselman S</searchLink>; Genitourinary Oncology Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY.<br /><searchLink fieldCode="AU" term="%22Barnett+E%22">Barnett E</searchLink>; Genitourinary Oncology Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY.<br /><searchLink fieldCode="AU" term="%22Autio+KA%22">Autio KA</searchLink>; Genitourinary Oncology Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY.<br /><searchLink fieldCode="AU" term="%22Danila+D%22">Danila D</searchLink>; Genitourinary Oncology Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY.<br /><searchLink fieldCode="AU" term="%22McHugh+D%22">McHugh D</searchLink>; Genitourinary Oncology Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY.<br /><searchLink fieldCode="AU" term="%22Morris+M%22">Morris M</searchLink>; Genitourinary Oncology Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY.<br /><searchLink fieldCode="AU" term="%22Rathkopf+D%22">Rathkopf D</searchLink>; Genitourinary Oncology Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY.<br /><searchLink fieldCode="AU" term="%22Scher+H%22">Scher H</searchLink>; Genitourinary Oncology Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY.<br /><searchLink fieldCode="AU" term="%22Slovin+S%22">Slovin S</searchLink>; Genitourinary Oncology Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY.<br /><searchLink fieldCode="AU" term="%22Kantoff+P%22">Kantoff P</searchLink>; Genitourinary Oncology Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY.; Convergent Therapeutics, Cambridge, MA.<br /><searchLink fieldCode="AU" term="%22Gopalan+A%22">Gopalan A</searchLink>; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY.<br /><searchLink fieldCode="AU" term="%22Solit+DB%22">Solit DB</searchLink>; Genitourinary Oncology Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY.; Marie-Josée and Henry R. Kravis Center for Molecular Oncology, Memorial Sloan Kettering Cancer Center, New York, NY.; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY.<br /><searchLink fieldCode="AU" term="%22Wibmer+A%22">Wibmer A</searchLink>; Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY.<br /><searchLink fieldCode="AU" term="%22Schultz+N%22">Schultz N</searchLink>; Department of Epidemiology & Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY.; Marie-Josée and Henry R. Kravis Center for Molecular Oncology, Memorial Sloan Kettering Cancer Center, New York, NY.<br /><searchLink fieldCode="AU" term="%22Abida+W%22">Abida W</searchLink>; Genitourinary Oncology Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY.
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