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Integrating physical healthcare into psychiatry for severe mental illness: A narrative review and position statement from the ECNP PAN-Health group.

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Title: Integrating physical healthcare into psychiatry for severe mental illness: A narrative review and position statement from the ECNP PAN-Health group.
Authors: Nielsen RE; Department of Clinical Medicine, Aalborg University, Aalborg, Denmark.; Department of Psychiatry, Aalborg University Hospital, Aalborg, Denmark., Taipale H; Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden.; Center for Psychiatry Research, Stockholm City Council, Stockholm, Sweden.; Department of Forensic Psychiatry, University of Eastern Finland, Niuvanniemi Hospital, Kuopio, Finland.; School of Pharmacy, University of Eastern Finland, Kuopio, Finland., Cortese S; Developmental EPI (Evidence Synthesis, Prediction, Implementation) Lab, Centre for Innovation in Mental Health, School of Psychology, Faculty of Environmental and Life Sciences, University of Southampton, Southampton, UK.; Hampshire and Isle of Wight Healthcare NHS Foundation Trust, Southampton, UK.; Clinical and Experimental Sciences (CNS and Psychiatry), Faculty of Medicine, University of Southampton, Southampton, UK.; Hassenfeld Children's Hospital at NYU Langone, New York University Child Study Center, New York City, New York, USA.; DiMePRe-J-Department of Precision and Rigenerative Medicine-Jonic Area, University of Bari 'Aldo Moro', Bari, Italy., Dragioti E; University of Ioannina, Research Laboratory Psychology of Patients, Families & Health Professionals, Department of Nursing, School of Health Sciences, Ioannina, Greece., Du Rietz E; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden., Firth J; Division of Psychology and Mental Health, The University of Manchester, Manchester, UK., Fusar-Poli P; Early Psychosis: Interventions and Clinical-Detection (EPIC) Lab, Department of Psychosis Studies, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK.; South London and Maudsley NHS Foundation Trust, London, UK.; Department of Brain and Behavioral Sciences, University of Pavia, Pavia, Italy., Hartman C; University of Groningen, University Medical Center Groningen, Interdisciplinary Centre Psychopathology and Emotion Regulation, the Netherlands., Holt RI; Human Development and Health, Faculty of Medicine, University of Southampton, Southampton, UK.; Southampton National Institute for Health Research Biomedical Research Centre, University Hospital Southampton NHS Foundation Trust, Southampton, SO16 6YD, UK., Høye A; Department of Clinical Medicine, UiT the Arctic University of Norway and Department of Mental Health and Substance Abuse, University Hospital of North Norway, Tromsø, Norway., Koyanagi A; Research and Development Unit, Parc Sanitari Sant Joan de Déu, CIBERSAM, ISCIII, Dr. Antoni Pujadas, 42, Sant Boi de Llobregat, 08830, Barcelona, Spain.; ICREA, Pg. Lluis Companys 23, 08010, Barcelona, Spain., Larsson H; Developmental EPI (Evidence Synthesis, Prediction, Implementation) Lab, Centre for Innovation in Mental Health, School of Psychology, Faculty of Environmental and Life Sciences, University of Southampton, Southampton, UK.; School of Medical Sciences, Örebro University, Örebro, Sweden.; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden., Lehto K; Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia., Lindgren P; Department of Learning, Informatics, Management and Ethics, Karolinska Institutet, Stockholm, Sweden.; The Swedish Institute for Health Economics, Lund, Sweden., Manchia M; Section of Psychiatry, Department of Medical Sciences and Public Health, University of Cagliari, Cagliari, Italy.; Unit of Clinical Psychiatry, University Hospital Agency of Cagliari, Cagliari, Italy.; Department of Pharmacology, Dalhousie University, Halifax, Nova Scotia, Canada., Nordentoft M; Mental Health Centre Copenhagen, Department of Clinical Medicine, Copenhagen University Hospital, Denmark., Skonieczna-Żydecka K; Department of Biochemical Science, Pomeranian Medical University in Szczecin, 71-460, Szczecin, Poland., Stubbs B; Division of Social Psychiatry, Department of Psychiatry and Psychotherapy, Medical University of Vienna, 1090 Vienna, Austria.; Comprehensive Center for Clinical Neurosciences and Mental Health, Medical University of Vienna, 1090 Vienna, Austria., Vancampfort D; Department of Rehabilitation Sciences, KU Leuven, Leuven, Belgium.; University Psychiatric Centre KU Leuven, Kortenberg, Leuven, Belgium., Brandt L; Charité - Universitätsmedizin Berlin, Department of Psychiatry and Neurosciences, Berlin, Germany.; German Center for Mental Health (DZPG) - Partner Site Berlin-Potsdam, Berlin, Germany., Marx W; Institute for Mental and Physical Health and Clinical Translation, Food & Mood Centre, School of Medicine, Deakin University, Barwon Health, Geelong, Victoria, Australia, 3220., Reininghaus E; Division of Psychiatry and Psychotherapeutic Medicine, Research Unit for Bipolar Affective Disorder, Medical University of Graz, Graz, Austria., Vieta E; Department of Medicine, Faculty of Medicine and Health Sciences, Institute of Neurosciences (UBNeuro), University of Barcelona (UB), C. Casanova, 143, 08036, Barcelona, Catalonia, Spain.; Bipolar and Depressive Disorders Unit, Hospìtal Clinic de Barcelona, c. Villarroel, 170, 08036, Barcelona, Catalonia, Spain.; Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), c. Villarroel, 170, 08036, Barcelona, Catalonia, Spain.; Centro de Investigación Biomédica en Red de Salud Mental (CIBERSAM), Instituto de Salud Carlos III, Madrid, Spain., De Prisco M; Department of Medicine, Faculty of Medicine and Health Sciences, Institute of Neurosciences (UBNeuro), University of Barcelona (UB), C. Casanova, 143, 08036, Barcelona, Catalonia, Spain.; Bipolar and Depressive Disorders Unit, Hospìtal Clinic de Barcelona, c. Villarroel, 170, 08036, Barcelona, Catalonia, Spain.; Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), c. Villarroel, 170, 08036, Barcelona, Catalonia, Spain.; Centro de Investigación Biomédica en Red de Salud Mental (CIBERSAM), Instituto de Salud Carlos III, Madrid, Spain., Boyer L; CEReSS-Health Services Research and Quality of Life Center, Aix-Marseille University, France., Correll CU; Department of Child and Adolescent Psychiatry, Charité Universitätsmedizin, Berlin, Germany.; Department of Psychiatry, Zucker Hillside Hospital, Northwell Health, Glen Oaks, NY, USA.; Department of Psychiatry and Molecular Medicine, Zucker School of Medicine at Hofstra/Northwell, Hempstead, NY, USA., Solmi M; Department of Child and Adolescent Psychiatry, Charité Universitätsmedizin, Berlin, Germany.; Department of Psychiatry, University of Ottawa, Ottawa, ON, Canada.; Department of Mental Health, Ottawa Hospital, Ottawa, ON, Canada.; Ottawa Hospital Research Institute (OHRI) Clinical Epidemiology Program, University of Ottawa, Ottawa, ON, Canada.; School of Epidemiology and Public Health, Faculty of Medicine, University of Ottawa, Ottawa, ON, Canada.
Corporate Authors: ECNP Physical And meNtal Health Thematic Working Group (PAN-Health)
Source: Neuroscience applied [Neurosci Appl] 2026 Feb 28; Vol. 5, pp. 106993. Date of Electronic Publication: 2026 Feb 28 (Print Publication: 2026).
Publication Type: Journal Article; Review
Journal Info: Publisher: Elsevier B.V Country of Publication: Netherlands NLM ID: 9918917644506676 Publication Model: eCollection Cited Medium: Internet ISSN: 2772-4085 (Electronic) Linking ISSN: 27724085 NLM ISO Abbreviation: Neurosci Appl Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Nielsen+RE%22">Nielsen RE</searchLink>; Department of Clinical Medicine, Aalborg University, Aalborg, Denmark.; Department of Psychiatry, Aalborg University Hospital, Aalborg, Denmark.<br /><searchLink fieldCode="AU" term="%22Taipale+H%22">Taipale H</searchLink>; Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden.; Center for Psychiatry Research, Stockholm City Council, Stockholm, Sweden.; Department of Forensic Psychiatry, University of Eastern Finland, Niuvanniemi Hospital, Kuopio, Finland.; School of Pharmacy, University of Eastern Finland, Kuopio, Finland.<br /><searchLink fieldCode="AU" term="%22Cortese+S%22">Cortese S</searchLink>; Developmental EPI (Evidence Synthesis, Prediction, Implementation) Lab, Centre for Innovation in Mental Health, School of Psychology, Faculty of Environmental and Life Sciences, University of Southampton, Southampton, UK.; Hampshire and Isle of Wight Healthcare NHS Foundation Trust, Southampton, UK.; Clinical and Experimental Sciences (CNS and Psychiatry), Faculty of Medicine, University of Southampton, Southampton, UK.; Hassenfeld Children's Hospital at NYU Langone, New York University Child Study Center, New York City, New York, USA.; DiMePRe-J-Department of Precision and Rigenerative Medicine-Jonic Area, University of Bari 'Aldo Moro', Bari, Italy.<br /><searchLink fieldCode="AU" term="%22Dragioti+E%22">Dragioti E</searchLink>; University of Ioannina, Research Laboratory Psychology of Patients, Families & Health Professionals, Department of Nursing, School of Health Sciences, Ioannina, Greece.<br /><searchLink fieldCode="AU" term="%22Du+Rietz+E%22">Du Rietz E</searchLink>; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Firth+J%22">Firth J</searchLink>; Division of Psychology and Mental Health, The University of Manchester, Manchester, UK.<br /><searchLink fieldCode="AU" term="%22Fusar-Poli+P%22">Fusar-Poli P</searchLink>; Early Psychosis: Interventions and Clinical-Detection (EPIC) Lab, Department of Psychosis Studies, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK.; South London and Maudsley NHS Foundation Trust, London, UK.; Department of Brain and Behavioral Sciences, University of Pavia, Pavia, Italy.<br /><searchLink fieldCode="AU" term="%22Hartman+C%22">Hartman C</searchLink>; University of Groningen, University Medical Center Groningen, Interdisciplinary Centre Psychopathology and Emotion Regulation, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Holt+RI%22">Holt RI</searchLink>; Human Development and Health, Faculty of Medicine, University of Southampton, Southampton, UK.; Southampton National Institute for Health Research Biomedical Research Centre, University Hospital Southampton NHS Foundation Trust, Southampton, SO16 6YD, UK.<br /><searchLink fieldCode="AU" term="%22Høye+A%22">Høye A</searchLink>; Department of Clinical Medicine, UiT the Arctic University of Norway and Department of Mental Health and Substance Abuse, University Hospital of North Norway, Tromsø, Norway.<br /><searchLink fieldCode="AU" term="%22Koyanagi+A%22">Koyanagi A</searchLink>; Research and Development Unit, Parc Sanitari Sant Joan de Déu, CIBERSAM, ISCIII, Dr. Antoni Pujadas, 42, Sant Boi de Llobregat, 08830, Barcelona, Spain.; ICREA, Pg. Lluis Companys 23, 08010, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Larsson+H%22">Larsson H</searchLink>; Developmental EPI (Evidence Synthesis, Prediction, Implementation) Lab, Centre for Innovation in Mental Health, School of Psychology, Faculty of Environmental and Life Sciences, University of Southampton, Southampton, UK.; School of Medical Sciences, Örebro University, Örebro, Sweden.; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Lehto+K%22">Lehto K</searchLink>; Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia.<br /><searchLink fieldCode="AU" term="%22Lindgren+P%22">Lindgren P</searchLink>; Department of Learning, Informatics, Management and Ethics, Karolinska Institutet, Stockholm, Sweden.; The Swedish Institute for Health Economics, Lund, Sweden.<br /><searchLink fieldCode="AU" term="%22Manchia+M%22">Manchia M</searchLink>; Section of Psychiatry, Department of Medical Sciences and Public Health, University of Cagliari, Cagliari, Italy.; Unit of Clinical Psychiatry, University Hospital Agency of Cagliari, Cagliari, Italy.; Department of Pharmacology, Dalhousie University, Halifax, Nova Scotia, Canada.<br /><searchLink fieldCode="AU" term="%22Nordentoft+M%22">Nordentoft M</searchLink>; Mental Health Centre Copenhagen, Department of Clinical Medicine, Copenhagen University Hospital, Denmark.<br /><searchLink fieldCode="AU" term="%22Skonieczna-Żydecka+K%22">Skonieczna-Żydecka K</searchLink>; Department of Biochemical Science, Pomeranian Medical University in Szczecin, 71-460, Szczecin, Poland.<br /><searchLink fieldCode="AU" term="%22Stubbs+B%22">Stubbs B</searchLink>; Division of Social Psychiatry, Department of Psychiatry and Psychotherapy, Medical University of Vienna, 1090 Vienna, Austria.; Comprehensive Center for Clinical Neurosciences and Mental Health, Medical University of Vienna, 1090 Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Vancampfort+D%22">Vancampfort D</searchLink>; Department of Rehabilitation Sciences, KU Leuven, Leuven, Belgium.; University Psychiatric Centre KU Leuven, Kortenberg, Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Brandt+L%22">Brandt L</searchLink>; Charité - Universitätsmedizin Berlin, Department of Psychiatry and Neurosciences, Berlin, Germany.; German Center for Mental Health (DZPG) - Partner Site Berlin-Potsdam, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Marx+W%22">Marx W</searchLink>; Institute for Mental and Physical Health and Clinical Translation, Food & Mood Centre, School of Medicine, Deakin University, Barwon Health, Geelong, Victoria, Australia, 3220.<br /><searchLink fieldCode="AU" term="%22Reininghaus+E%22">Reininghaus E</searchLink>; Division of Psychiatry and Psychotherapeutic Medicine, Research Unit for Bipolar Affective Disorder, Medical University of Graz, Graz, Austria.<br /><searchLink fieldCode="AU" term="%22Vieta+E%22">Vieta E</searchLink>; Department of Medicine, Faculty of Medicine and Health Sciences, Institute of Neurosciences (UBNeuro), University of Barcelona (UB), C. 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