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Engineering programmable CAR and antigen pairing via drug-gated light activation.

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Title: Engineering programmable CAR and antigen pairing via drug-gated light activation.
Authors: Huang Z; Alfred E. Mann Department of Biomedical Engineering, University of Southern California, Los Angeles, CA, USA.; Shu Chien-Gene Lay Department of Bioengineering, Institute of Engineering in Medicine, University of California San Diego, La Jolla, CA, USA.; State Key Laboratory of Ultrasound in Medicine and Engineering, Chongqing Medical University, Chongqing, 400016, China., Limsakul P; Shu Chien-Gene Lay Department of Bioengineering, Institute of Engineering in Medicine, University of California San Diego, La Jolla, CA, USA.; Division of Physical Science, Faculty of Science, Prince of Songkla University, Songkhla, Thailand., Wu Y; Shu Chien-Gene Lay Department of Bioengineering, Institute of Engineering in Medicine, University of California San Diego, La Jolla, CA, USA.; National Biomedical Imaging Center, College of Future Technology, Peking University, Beijing, 100871, China., Guo T; Alfred E. Mann Department of Biomedical Engineering, University of Southern California, Los Angeles, CA, USA., Wang Y; Alfred E. Mann Department of Biomedical Engineering, University of Southern California, Los Angeles, CA, USA., Wu Z; Alfred E. Mann Department of Biomedical Engineering, University of Southern California, Los Angeles, CA, USA., Zhu L; Alfred E. Mann Department of Biomedical Engineering, University of Southern California, Los Angeles, CA, USA., Allen ME; Shu Chien-Gene Lay Department of Bioengineering, Institute of Engineering in Medicine, University of California San Diego, La Jolla, CA, USA., Liu L; Alfred E. Mann Department of Biomedical Engineering, University of Southern California, Los Angeles, CA, USA.; Shu Chien-Gene Lay Department of Bioengineering, Institute of Engineering in Medicine, University of California San Diego, La Jolla, CA, USA., Wang Y; Alfred E. Mann Department of Biomedical Engineering, University of Southern California, Los Angeles, CA, USA. ywang283@usc.edu.; Shu Chien-Gene Lay Department of Bioengineering, Institute of Engineering in Medicine, University of California San Diego, La Jolla, CA, USA. ywang283@usc.edu.
Source: Nature communications [Nat Commun] 2026 Mar 19; Vol. 17 (1). Date of Electronic Publication: 2026 Mar 19.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Huang+Z%22">Huang Z</searchLink>; Alfred E. Mann Department of Biomedical Engineering, University of Southern California, Los Angeles, CA, USA.; Shu Chien-Gene Lay Department of Bioengineering, Institute of Engineering in Medicine, University of California San Diego, La Jolla, CA, USA.; State Key Laboratory of Ultrasound in Medicine and Engineering, Chongqing Medical University, Chongqing, 400016, China.<br /><searchLink fieldCode="AU" term="%22Limsakul+P%22">Limsakul P</searchLink>; Shu Chien-Gene Lay Department of Bioengineering, Institute of Engineering in Medicine, University of California San Diego, La Jolla, CA, USA.; Division of Physical Science, Faculty of Science, Prince of Songkla University, Songkhla, Thailand.<br /><searchLink fieldCode="AU" term="%22Wu+Y%22">Wu Y</searchLink>; Shu Chien-Gene Lay Department of Bioengineering, Institute of Engineering in Medicine, University of California San Diego, La Jolla, CA, USA.; National Biomedical Imaging Center, College of Future Technology, Peking University, Beijing, 100871, China.<br /><searchLink fieldCode="AU" term="%22Guo+T%22">Guo T</searchLink>; Alfred E. Mann Department of Biomedical Engineering, University of Southern California, Los Angeles, CA, USA.<br /><searchLink fieldCode="AU" term="%22Wang+Y%22">Wang Y</searchLink>; Alfred E. Mann Department of Biomedical Engineering, University of Southern California, Los Angeles, CA, USA.<br /><searchLink fieldCode="AU" term="%22Wu+Z%22">Wu Z</searchLink>; Alfred E. Mann Department of Biomedical Engineering, University of Southern California, Los Angeles, CA, USA.<br /><searchLink fieldCode="AU" term="%22Zhu+L%22">Zhu L</searchLink>; Alfred E. Mann Department of Biomedical Engineering, University of Southern California, Los Angeles, CA, USA.<br /><searchLink fieldCode="AU" term="%22Allen+ME%22">Allen ME</searchLink>; Shu Chien-Gene Lay Department of Bioengineering, Institute of Engineering in Medicine, University of California San Diego, La Jolla, CA, USA.<br /><searchLink fieldCode="AU" term="%22Liu+L%22">Liu L</searchLink>; Alfred E. Mann Department of Biomedical Engineering, University of Southern California, Los Angeles, CA, USA.; Shu Chien-Gene Lay Department of Bioengineering, Institute of Engineering in Medicine, University of California San Diego, La Jolla, CA, USA.<br /><searchLink fieldCode="AU" term="%22Wang+Y%22">Wang Y</searchLink>; Alfred E. Mann Department of Biomedical Engineering, University of Southern California, Los Angeles, CA, USA. ywang283@usc.edu.; Shu Chien-Gene Lay Department of Bioengineering, Institute of Engineering in Medicine, University of California San Diego, La Jolla, CA, USA. ywang283@usc.edu.
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  Data: <searchLink fieldCode="JN" term="%22101528555%22">Nature communications</searchLink> [Nat Commun] 2026 Mar 19; Vol. 17 (1). <i>Date of Electronic Publication: </i>2026 Mar 19.
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              Text: 2026 Mar 19
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