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Amplitude integrated electroencephalography for neonatal seizure detection: an alternative opinion to the 2025 Cochrane review.

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Title: Amplitude integrated electroencephalography for neonatal seizure detection: an alternative opinion to the 2025 Cochrane review.
Authors: Variane GFT; Department of Pediatrics, Division of Neonatology, Irmandade da Santa Casa de Misericordia de Sao Paulo, São Paulo, Brazil. gabriel.variane@pbsf.com.br.; Protecting Brains & Saving Futures, São Paulo, Brazil. gabriel.variane@pbsf.com.br.; Faculdade de Ciências Médicas da Santa Casa de São Paulo, São Paulo, Brazil. gabriel.variane@pbsf.com.br., Van Meurs K; Division of Neonatal & Developmental Medicine, Stanford University School of Medicine, Palo Alto, CA, USA., de Vries LS; Department of Pediatrics, Division of Neonatology, Willem-Alexander Children's Hospital, Leiden University Medical Center, Leiden, The Netherlands., Bonifacio SL; Division of Neonatal & Developmental Medicine, Stanford University School of Medicine, Palo Alto, CA, USA., Boylan GB; Department of Pediatrics & Child Health, University College Cork, Cork, Ireland.; INFANT Research Centre, University College Cork, Cork, Ireland., Chalak L; Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX, USA., Clancy R; University of Pennsylvania School of Medicine, Philadelphia, PA, USA.; Children's Hospital of Philadelphia, Philadelphia, PA, USA., El-Dib M; Division of Newborn Medicine, Department of Pediatrics, Mass General Brigham for Children, Harvard Medical School, Boston, MA, USA., Greisen G; Department of Neonatology, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark.; Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark., Hunt RW; Department of Paediatrics, Monash University, Melbourne, VIC, Australia.; Department of Newborn Medicine, Monash Health, Clayton, VIC, Australia.; Cerebral Palsy Alliance, Sydney, NSW, Australia., Inder T; Center for Perinatal and Infant Research, Radys Children's Hospital of Orange County, Irvine, CA, USA.; Department of Pediatrics, University of California, Irvine, CA, USA., Klebermass-Schrehof K; Department of Pediatrics and Adolescent Medicine, Division of Neonatology, Intensive Care and Neuropediatrics, Comprehensive Center of Pediatrics, Medical University of Vienna, Vienna, Austria., McNamara PJ; Department of Pediatrics, University of Iowa Stead Family Children's Hospital, Iowa City, IA, USA., Numis AL; Department of Neurology, University of California, San Francisco, CA, USA., Sewell E; Emory University School of Medicine, Atlanta, GA, USA.; Children's Healthcare of Atlanta, Atlanta, GA, USA., Shah DK; Royal London Hospital, London, UK.; Blizard Institute, Queen Mary University of London, London, UK., Shany E; Neonatal Department, Saban Children Hospital, Soroka University Medical Center, Be'er Sheva, Israel.; Pediatrics Division, Faculty of Health Sciences, Ben-Gurion University of the Negev, Be'er Sheva, Israel., Szabo M; Department of Neonatology, Pediatric Center, Semmelweis University, Budapest, Hungary., Thoresen M; Neonatal Neuroscience, Translational Health Sciences, University of Bristol, Bristol, UK.; Physiology Oslo Medical School, Division of Basic Medical Sciences, University of Oslo, Oslo, Norway., Vanhatalo S; BABA Center, Pediatric Research Center, New Children's Hospital, Helsinki University Hospital, Helsinki, Finland.; Department of Physiology and Clinical Neurophysiology, University of Helsinki, Helsinki, Finland., Wang L; Neonatal Medical Center, Children's Hospital of Fudan University, Shanghai, China.; National Children's Medical Center, Shanghai, China.; National Health Commission Key Laboratory of Neonatal Diseases, Shanghai, China., Hellström-Westas L; Department of Women's and Children's Health, Uppsala University, Uppsala, Sweden.
Source: Pediatric research [Pediatr Res] 2026 Mar 19. Date of Electronic Publication: 2026 Mar 19.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: United States NLM ID: 0100714 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1530-0447 (Electronic) Linking ISSN: 00313998 NLM ISO Abbreviation: Pediatr Res Subsets: MEDLINE
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  Data: Amplitude integrated electroencephalography for neonatal seizure detection: an alternative opinion to the 2025 Cochrane review.
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  Data: <searchLink fieldCode="AU" term="%22Variane+GFT%22">Variane GFT</searchLink>; Department of Pediatrics, Division of Neonatology, Irmandade da Santa Casa de Misericordia de Sao Paulo, São Paulo, Brazil. gabriel.variane@pbsf.com.br.; Protecting Brains & Saving Futures, São Paulo, Brazil. gabriel.variane@pbsf.com.br.; Faculdade de Ciências Médicas da Santa Casa de São Paulo, São Paulo, Brazil. gabriel.variane@pbsf.com.br.<br /><searchLink fieldCode="AU" term="%22Van+Meurs+K%22">Van Meurs K</searchLink>; Division of Neonatal & Developmental Medicine, Stanford University School of Medicine, Palo Alto, CA, USA.<br /><searchLink fieldCode="AU" term="%22de+Vries+LS%22">de Vries LS</searchLink>; Department of Pediatrics, Division of Neonatology, Willem-Alexander Children's Hospital, Leiden University Medical Center, Leiden, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Bonifacio+SL%22">Bonifacio SL</searchLink>; Division of Neonatal & Developmental Medicine, Stanford University School of Medicine, Palo Alto, CA, USA.<br /><searchLink fieldCode="AU" term="%22Boylan+GB%22">Boylan GB</searchLink>; Department of Pediatrics & Child Health, University College Cork, Cork, Ireland.; INFANT Research Centre, University College Cork, Cork, Ireland.<br /><searchLink fieldCode="AU" term="%22Chalak+L%22">Chalak L</searchLink>; Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX, USA.<br /><searchLink fieldCode="AU" term="%22Clancy+R%22">Clancy R</searchLink>; University of Pennsylvania School of Medicine, Philadelphia, PA, USA.; Children's Hospital of Philadelphia, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22El-Dib+M%22">El-Dib M</searchLink>; Division of Newborn Medicine, Department of Pediatrics, Mass General Brigham for Children, Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Greisen+G%22">Greisen G</searchLink>; Department of Neonatology, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark.; Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Hunt+RW%22">Hunt RW</searchLink>; Department of Paediatrics, Monash University, Melbourne, VIC, Australia.; Department of Newborn Medicine, Monash Health, Clayton, VIC, Australia.; Cerebral Palsy Alliance, Sydney, NSW, Australia.<br /><searchLink fieldCode="AU" term="%22Inder+T%22">Inder T</searchLink>; Center for Perinatal and Infant Research, Radys Children's Hospital of Orange County, Irvine, CA, USA.; Department of Pediatrics, University of California, Irvine, CA, USA.<br /><searchLink fieldCode="AU" term="%22Klebermass-Schrehof+K%22">Klebermass-Schrehof K</searchLink>; Department of Pediatrics and Adolescent Medicine, Division of Neonatology, Intensive Care and Neuropediatrics, Comprehensive Center of Pediatrics, Medical University of Vienna, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22McNamara+PJ%22">McNamara PJ</searchLink>; Department of Pediatrics, University of Iowa Stead Family Children's Hospital, Iowa City, IA, USA.<br /><searchLink fieldCode="AU" term="%22Numis+AL%22">Numis AL</searchLink>; Department of Neurology, University of California, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Sewell+E%22">Sewell E</searchLink>; Emory University School of Medicine, Atlanta, GA, USA.; Children's Healthcare of Atlanta, Atlanta, GA, USA.<br /><searchLink fieldCode="AU" term="%22Shah+DK%22">Shah DK</searchLink>; Royal London Hospital, London, UK.; Blizard Institute, Queen Mary University of London, London, UK.<br /><searchLink fieldCode="AU" term="%22Shany+E%22">Shany E</searchLink>; Neonatal Department, Saban Children Hospital, Soroka University Medical Center, Be'er Sheva, Israel.; Pediatrics Division, Faculty of Health Sciences, Ben-Gurion University of the Negev, Be'er Sheva, Israel.<br /><searchLink fieldCode="AU" term="%22Szabo+M%22">Szabo M</searchLink>; Department of Neonatology, Pediatric Center, Semmelweis University, Budapest, Hungary.<br /><searchLink fieldCode="AU" term="%22Thoresen+M%22">Thoresen M</searchLink>; Neonatal Neuroscience, Translational Health Sciences, University of Bristol, Bristol, UK.; Physiology Oslo Medical School, Division of Basic Medical Sciences, University of Oslo, Oslo, Norway.<br /><searchLink fieldCode="AU" term="%22Vanhatalo+S%22">Vanhatalo S</searchLink>; BABA Center, Pediatric Research Center, New Children's Hospital, Helsinki University Hospital, Helsinki, Finland.; Department of Physiology and Clinical Neurophysiology, University of Helsinki, Helsinki, Finland.<br /><searchLink fieldCode="AU" term="%22Wang+L%22">Wang L</searchLink>; Neonatal Medical Center, Children's Hospital of Fudan University, Shanghai, China.; National Children's Medical Center, Shanghai, China.; National Health Commission Key Laboratory of Neonatal Diseases, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Hellström-Westas+L%22">Hellström-Westas L</searchLink>; Department of Women's and Children's Health, Uppsala University, Uppsala, Sweden.
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