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Diminishing returns of disease-modifying treatment in older participants of multiple sclerosis clinical trials.

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Title: Diminishing returns of disease-modifying treatment in older participants of multiple sclerosis clinical trials.
Authors: Strijbis E; Amsterdam UMC, Amsterdam, The Netherlands., Mostert J; Department of Neurology, Rijnstate Hospital, Arnhem, The Netherlands., D'Haeseleer M; Universitair Ziekenhuis Brussel, Brussels, Belgium; National Multiple Sclerosis Center, Melsbroek, Belgium., Moral E; Neurology, Hospital Universitario de Bellvitge, L'Hospitalet de Llobregat, Barcelona, Spain., Brieva Ruiz L; Neuroimmunology Group, Department of Neurology, Hospital Universitari Arnau de Vilanova, Lleida, Spain., Comtois J; Université de Montreal, Montreal, QC, Canada., Killestein J; Amsterdam UMC, Amsterdam, The Netherlands., Repovic P; Swedish Neuroscience Institute Multiple Sclerosis Center, Seattle, WA, USA., McPherson T; Biostatistics and Bioinformatics, Emory University, Atlanta, GA, USA., Cutter G; Department of Biostatistics, School of Public Health, University of Alabama at Birmingham, Birmingham, AL, USA., Koch M; Clinical Neurosciences, University of Calgary, Calgary, AB, Canada.
Source: Multiple sclerosis (Houndmills, Basingstoke, England) [Mult Scler] 2026 Apr; Vol. 32 (4), pp. 429-439. Date of Electronic Publication: 2026 Mar 20.
Publication Type: Journal Article
Journal Info: Publisher: SAGE Publications Country of Publication: England NLM ID: 9509185 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1477-0970 (Electronic) Linking ISSN: 13524585 NLM ISO Abbreviation: Mult Scler Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Diminishing returns of disease-modifying treatment in older participants of multiple sclerosis clinical trials.
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  Data: <searchLink fieldCode="AU" term="%22Strijbis+E%22">Strijbis E</searchLink>; Amsterdam UMC, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Mostert+J%22">Mostert J</searchLink>; Department of Neurology, Rijnstate Hospital, Arnhem, The Netherlands.<br /><searchLink fieldCode="AU" term="%22D'Haeseleer+M%22">D'Haeseleer M</searchLink>; Universitair Ziekenhuis Brussel, Brussels, Belgium; National Multiple Sclerosis Center, Melsbroek, Belgium.<br /><searchLink fieldCode="AU" term="%22Moral+E%22">Moral E</searchLink>; Neurology, Hospital Universitario de Bellvitge, L'Hospitalet de Llobregat, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Brieva+Ruiz+L%22">Brieva Ruiz L</searchLink>; Neuroimmunology Group, Department of Neurology, Hospital Universitari Arnau de Vilanova, Lleida, Spain.<br /><searchLink fieldCode="AU" term="%22Comtois+J%22">Comtois J</searchLink>; Université de Montreal, Montreal, QC, Canada.<br /><searchLink fieldCode="AU" term="%22Killestein+J%22">Killestein J</searchLink>; Amsterdam UMC, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Repovic+P%22">Repovic P</searchLink>; Swedish Neuroscience Institute Multiple Sclerosis Center, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22McPherson+T%22">McPherson T</searchLink>; Biostatistics and Bioinformatics, Emory University, Atlanta, GA, USA.<br /><searchLink fieldCode="AU" term="%22Cutter+G%22">Cutter G</searchLink>; Department of Biostatistics, School of Public Health, University of Alabama at Birmingham, Birmingham, AL, USA.<br /><searchLink fieldCode="AU" term="%22Koch+M%22">Koch M</searchLink>; Clinical Neurosciences, University of Calgary, Calgary, AB, Canada.
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  Data: <searchLink fieldCode="JN" term="%229509185%22">Multiple sclerosis (Houndmills, Basingstoke, England)</searchLink> [Mult Scler] 2026 Apr; Vol. 32 (4), pp. 429-439. <i>Date of Electronic Publication: </i>2026 Mar 20.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22SAGE+Publications%22">SAGE Publications </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>9509185 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1477-0970 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2213524585%22">13524585 </searchLink><i>NLM ISO Abbreviation: </i>Mult Scler <i>Subsets: </i>MEDLINE
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              Text: 2026 Apr
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