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Oncogenic GPRIN1 sustains proliferation and mitochondrial homeostasis via dual‑layer CDK1-PI3K/Akt signalling in gallbladder cancer.

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Title: Oncogenic GPRIN1 sustains proliferation and mitochondrial homeostasis via dual‑layer CDK1-PI3K/Akt signalling in gallbladder cancer.
Authors: Xu C; Department of Biliary Surgery, Zhongshan Hospital, Fudan University, Shanghai, China., Gong Z; Department of Biliary Surgery, Zhongshan Hospital, Fudan University, Shanghai, China., Ni X; Department of Biliary Surgery, Zhongshan Hospital, Fudan University, Shanghai, China., Nan L; Department of Biliary Surgery, Zhongshan Hospital, Fudan University, Shanghai, China., Sun W; Department of Biliary Surgery, Zhongshan Hospital, Fudan University, Shanghai, China., Liu H; Department of Biliary Surgery, Zhongshan Hospital, Fudan University, Shanghai, China., Luo X; Department of General Surgery, Xuhui Central Hospital, Fudan University, Shanghai, China. xuanmingluo@163.com., Li M; Department of Biliary Surgery, Zhongshan Hospital, Fudan University, Shanghai, China. li.min2@zs-hospital.sh.cn.
Source: Cell death & disease [Cell Death Dis] 2026 Mar 21; Vol. 17 (1). Date of Electronic Publication: 2026 Mar 21.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101524092 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-4889 (Electronic) NLM ISO Abbreviation: Cell Death Dis Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Oncogenic GPRIN1 sustains proliferation and mitochondrial homeostasis via dual‑layer CDK1-PI3K/Akt signalling in gallbladder cancer.
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  Data: <searchLink fieldCode="AU" term="%22Xu+C%22">Xu C</searchLink>; Department of Biliary Surgery, Zhongshan Hospital, Fudan University, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Gong+Z%22">Gong Z</searchLink>; Department of Biliary Surgery, Zhongshan Hospital, Fudan University, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Ni+X%22">Ni X</searchLink>; Department of Biliary Surgery, Zhongshan Hospital, Fudan University, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Nan+L%22">Nan L</searchLink>; Department of Biliary Surgery, Zhongshan Hospital, Fudan University, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Sun+W%22">Sun W</searchLink>; Department of Biliary Surgery, Zhongshan Hospital, Fudan University, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Liu+H%22">Liu H</searchLink>; Department of Biliary Surgery, Zhongshan Hospital, Fudan University, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Luo+X%22">Luo X</searchLink>; Department of General Surgery, Xuhui Central Hospital, Fudan University, Shanghai, China. xuanmingluo@163.com.<br /><searchLink fieldCode="AU" term="%22Li+M%22">Li M</searchLink>; Department of Biliary Surgery, Zhongshan Hospital, Fudan University, Shanghai, China. li.min2@zs-hospital.sh.cn.
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  Data: <searchLink fieldCode="JN" term="%22101524092%22">Cell death & disease</searchLink> [Cell Death Dis] 2026 Mar 21; Vol. 17 (1). <i>Date of Electronic Publication: </i>2026 Mar 21.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Pub%2E+Group%22">Nature Pub. Group </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101524092 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2041-4889 (Electronic) <i>NLM ISO Abbreviation: </i>Cell Death Dis <i>Subsets: </i>MEDLINE
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        Value: 10.1038/s41419-026-08550-2
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              Text: 2026 Mar 21
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