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Integration of plasma eMTBR-tau243 and p-tau217 in the diagnosis and stratification of Alzheimer's disease: a prospective cohort study.

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Title: Integration of plasma eMTBR-tau243 and p-tau217 in the diagnosis and stratification of Alzheimer's disease: a prospective cohort study.
Authors: Mattsson-Carlgren N; Clinical Memory Research Unit, Clinical Sciences Malmö, Lund University, Lund, Sweden; Memory Clinic, Skåne University Hospital, Lund University, Lund, Sweden; Wallenberg Center for Molecular Medicine, Lund University, Lund, Sweden. Electronic address: niklas.mattsson-carlgren@med.lu.se., Palmqvist S; Clinical Memory Research Unit, Clinical Sciences Malmö, Lund University, Lund, Sweden; Memory Clinic, Skåne University Hospital, Lund University, Lund, Sweden., Horie K; The Tracy Family SILQ Center, Washington University School of Medicine, St. Louis, MO, USA; Department of Neurology, Washington University School of Medicine, St. Louis, MO, USA; Eisai, Nutley, NJ, USA., Barthélemy N; The Tracy Family SILQ Center, Washington University School of Medicine, St. Louis, MO, USA; Department of Neurology, Washington University School of Medicine, St. Louis, MO, USA., Salvadó G; Clinical Memory Research Unit, Clinical Sciences Malmö, Lund University, Lund, Sweden; Barcelona Beta, Barcelona, Spain., Binette AP; Clinical Memory Research Unit, Clinical Sciences Malmö, Lund University, Lund, Sweden; Department of Physiology and Pharmacology, Université de Montréal, Montréal, Quebec, Canada; Centre de Recherche de l'Institut Universitaire de Gériatrie de Montréal, Montréal, Quebec, Canada., Tideman P; Clinical Memory Research Unit, Clinical Sciences Malmö, Lund University, Lund, Sweden., Morris JC; Department of Neurology, Washington University School of Medicine, St. Louis, MO, USA; Knight Alzheimer Disease Research Center, Washington University School of Medicine, St. Louis, MO, USA; Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO, USA., Benzinger TL; Knight Alzheimer Disease Research Center, Washington University School of Medicine, St. Louis, MO, USA; Mallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, MO, USA., Perrin RJ; Knight Alzheimer Disease Research Center, Washington University School of Medicine, St. Louis, MO, USA; Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO, USA., Janelidze S; Clinical Memory Research Unit, Clinical Sciences Malmö, Lund University, Lund, Sweden., Collij LE; Clinical Memory Research Unit, Clinical Sciences Malmö, Lund University, Lund, Sweden; Radiology and Nuclear Medicine, Amsterdam UMC, location VUmc, Amsterdam, Netherlands; Brain Imaging, Amsterdam Neuroscience, Amsterdam, Netherlands., Ossenkoppele R; Clinical Memory Research Unit, Clinical Sciences Malmö, Lund University, Lund, Sweden; Neurology, Alzheimer Center Amsterdam, Amsterdam UMC, location VUmc, Amsterdam, Netherlands; Neurodegeneration, Amsterdam Neuroscience, Amsterdam, Netherlands., Schindler SE; Department of Neurology, Washington University School of Medicine, St. Louis, MO, USA., Stomrud E; Clinical Memory Research Unit, Clinical Sciences Malmö, Lund University, Lund, Sweden; Memory Clinic, Skåne University Hospital, Lund University, Lund, Sweden., Bateman RJ; The Tracy Family SILQ Center, Washington University School of Medicine, St. Louis, MO, USA; Department of Neurology, Washington University School of Medicine, St. Louis, MO, USA; Knight Alzheimer Disease Research Center, Washington University School of Medicine, St. Louis, MO, USA; Hope Center for Neurological Disorders, Washington University School of Medicine, St. Louis, MO, USA., Hansson O; Clinical Memory Research Unit, Clinical Sciences Malmö, Lund University, Lund, Sweden.
Source: The Lancet. Neurology [Lancet Neurol] 2026 Apr; Vol. 25 (4), pp. 357-367.
Publication Type: Journal Article
Journal Info: Publisher: Lancet Pub. Group Country of Publication: England NLM ID: 101139309 Publication Model: Print Cited Medium: Internet ISSN: 1474-4465 (Electronic) Linking ISSN: 14744422 NLM ISO Abbreviation: Lancet Neurol Subsets: MEDLINE
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  Data: Integration of plasma eMTBR-tau243 and p-tau217 in the diagnosis and stratification of Alzheimer's disease: a prospective cohort study.
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  Data: <searchLink fieldCode="AU" term="%22Mattsson-Carlgren+N%22">Mattsson-Carlgren N</searchLink>; Clinical Memory Research Unit, Clinical Sciences Malmö, Lund University, Lund, Sweden; Memory Clinic, Skåne University Hospital, Lund University, Lund, Sweden; Wallenberg Center for Molecular Medicine, Lund University, Lund, Sweden. Electronic address: niklas.mattsson-carlgren@med.lu.se.<br /><searchLink fieldCode="AU" term="%22Palmqvist+S%22">Palmqvist S</searchLink>; Clinical Memory Research Unit, Clinical Sciences Malmö, Lund University, Lund, Sweden; Memory Clinic, Skåne University Hospital, Lund University, Lund, Sweden.<br /><searchLink fieldCode="AU" term="%22Horie+K%22">Horie K</searchLink>; The Tracy Family SILQ Center, Washington University School of Medicine, St. Louis, MO, USA; Department of Neurology, Washington University School of Medicine, St. Louis, MO, USA; Eisai, Nutley, NJ, USA.<br /><searchLink fieldCode="AU" term="%22Barthélemy+N%22">Barthélemy N</searchLink>; The Tracy Family SILQ Center, Washington University School of Medicine, St. Louis, MO, USA; Department of Neurology, Washington University School of Medicine, St. Louis, MO, USA.<br /><searchLink fieldCode="AU" term="%22Salvadó+G%22">Salvadó G</searchLink>; Clinical Memory Research Unit, Clinical Sciences Malmö, Lund University, Lund, Sweden; Barcelona Beta, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Binette+AP%22">Binette AP</searchLink>; Clinical Memory Research Unit, Clinical Sciences Malmö, Lund University, Lund, Sweden; Department of Physiology and Pharmacology, Université de Montréal, Montréal, Quebec, Canada; Centre de Recherche de l'Institut Universitaire de Gériatrie de Montréal, Montréal, Quebec, Canada.<br /><searchLink fieldCode="AU" term="%22Tideman+P%22">Tideman P</searchLink>; Clinical Memory Research Unit, Clinical Sciences Malmö, Lund University, Lund, Sweden.<br /><searchLink fieldCode="AU" term="%22Morris+JC%22">Morris JC</searchLink>; Department of Neurology, Washington University School of Medicine, St. Louis, MO, USA; Knight Alzheimer Disease Research Center, Washington University School of Medicine, St. Louis, MO, USA; Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO, USA.<br /><searchLink fieldCode="AU" term="%22Benzinger+TL%22">Benzinger TL</searchLink>; Knight Alzheimer Disease Research Center, Washington University School of Medicine, St. Louis, MO, USA; Mallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, MO, USA.<br /><searchLink fieldCode="AU" term="%22Perrin+RJ%22">Perrin RJ</searchLink>; Knight Alzheimer Disease Research Center, Washington University School of Medicine, St. Louis, MO, USA; Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO, USA.<br /><searchLink fieldCode="AU" term="%22Janelidze+S%22">Janelidze S</searchLink>; Clinical Memory Research Unit, Clinical Sciences Malmö, Lund University, Lund, Sweden.<br /><searchLink fieldCode="AU" term="%22Collij+LE%22">Collij LE</searchLink>; Clinical Memory Research Unit, Clinical Sciences Malmö, Lund University, Lund, Sweden; Radiology and Nuclear Medicine, Amsterdam UMC, location VUmc, Amsterdam, Netherlands; Brain Imaging, Amsterdam Neuroscience, Amsterdam, Netherlands.<br /><searchLink fieldCode="AU" term="%22Ossenkoppele+R%22">Ossenkoppele R</searchLink>; Clinical Memory Research Unit, Clinical Sciences Malmö, Lund University, Lund, Sweden; Neurology, Alzheimer Center Amsterdam, Amsterdam UMC, location VUmc, Amsterdam, Netherlands; Neurodegeneration, Amsterdam Neuroscience, Amsterdam, Netherlands.<br /><searchLink fieldCode="AU" term="%22Schindler+SE%22">Schindler SE</searchLink>; Department of Neurology, Washington University School of Medicine, St. Louis, MO, USA.<br /><searchLink fieldCode="AU" term="%22Stomrud+E%22">Stomrud E</searchLink>; Clinical Memory Research Unit, Clinical Sciences Malmö, Lund University, Lund, Sweden; Memory Clinic, Skåne University Hospital, Lund University, Lund, Sweden.<br /><searchLink fieldCode="AU" term="%22Bateman+RJ%22">Bateman RJ</searchLink>; The Tracy Family SILQ Center, Washington University School of Medicine, St. Louis, MO, USA; Department of Neurology, Washington University School of Medicine, St. Louis, MO, USA; Knight Alzheimer Disease Research Center, Washington University School of Medicine, St. Louis, MO, USA; Hope Center for Neurological Disorders, Washington University School of Medicine, St. Louis, MO, USA.<br /><searchLink fieldCode="AU" term="%22Hansson+O%22">Hansson O</searchLink>; Clinical Memory Research Unit, Clinical Sciences Malmö, Lund University, Lund, Sweden.
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