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Genome-wide association study reveals two novel genetic loci associated with chronic lung allograft dysfunction.

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Title: Genome-wide association study reveals two novel genetic loci associated with chronic lung allograft dysfunction.
Authors: Brocard S; Nantes Université, Centrale Nantes, CHU Nantes, Inserm, Center for Research in Transplantation and Translational Immunology, UMR 1064, ITUN, Nantes, France; IMT Atlantique - DAPI - Département Automatique, Productique et Informatique, Nantes, France., Mauduit V; Nantes Université, Centrale Nantes, CHU Nantes, Inserm, Center for Research in Transplantation and Translational Immunology, UMR 1064, ITUN, Nantes, France., Morin M; Nantes Université, Centrale Nantes, CHU Nantes, Inserm, Center for Research in Transplantation and Translational Immunology, UMR 1064, ITUN, Nantes, France., Boussamet L; Nantes Université, Centrale Nantes, CHU Nantes, Inserm, Center for Research in Transplantation and Translational Immunology, UMR 1064, ITUN, Nantes, France., Silva NDSB; Nantes Université, Centrale Nantes, CHU Nantes, Inserm, Center for Research in Transplantation and Translational Immunology, UMR 1064, ITUN, Nantes, France; São Paulo State University, Molecular Genetics and Bioinformatics Laboratory, School of Medicine, Botucatu, State of São Paulo, Brazil., Durand A; Nantes Université, Centrale Nantes, CHU Nantes, Inserm, Center for Research in Transplantation and Translational Immunology, UMR 1064, ITUN, Nantes, France., Halitim P; Nantes Université, Centrale Nantes, CHU Nantes, Inserm, Center for Research in Transplantation and Translational Immunology, UMR 1064, ITUN, Nantes, France., Renaud-Picard B; Department of Respiratory Medicine and Strasbourg Lung Transplant Program, Hôpitaux Universitaires de Strasbourg, Strasbourg, France; Université de Strasbourg, Inserm UMR 1260, Strasbourg, France., Coiffard B; Aix Marseille Univ, Department of Respiratory Medicine and Lung Transplantation, APHM, Hôpital Nord, Marseille, France., Demant X; Service de Pneumologie, Centre Hospitalier Universitaire de Bordeaux, Pessac, France., Falque L; Service Hospitalier Universitaire de Pneumologie et Physiologie, CHU Grenoble Alpes, Pôle Thorax et Vaisseaux, Grenoble, France., Le Pavec J; Service de Pneumologie et Transplantation Pulmonaire, Groupe hospitalier Marie-Lannelongue -Saint Joseph, Le Plessis-Robinson, Université Paris-Saclay, Le Kremlin BicÊtre, UMR_S 999, Université Paris-Sud, INSERM, France., Roux A; Pneumology, Adult Cystic Fibrosis Center and Lung Transplantation Department Hôpital Foch, Suresnes, Université de Versailles Saint Quentin Paris-Saclay, INRAe UMR 0892, Paris Transplant Group, Paris, France., Villeneuve T; CHU Toulouse, Service de Pneumologie, Université Toulouse III-Paul Sabatier, Toulouse, France., Knoop C; Service de Pneumologie, CHU Erasme, Bruxelles, Belgium., Merveilleux C; Université de Lyon, Université Lyon 1, PSL, EPHE, INRAE, IVPC, hospices civils de Lyon, groupement hospitalier est, service de pneumologie, Orphalung, RESPIFIL, Lyon, France., Salpin M; APHP Nord-Université Paris Cité, Hôpital Bichat, Service de Pneumologie B et Transplantation Pulmonaire, Université Paris Cité, PHERE UMRS 1152, Paris, France., Carlier N; APHP, Service de Pneumologie, Hôpital Cochin, Paris, France., Gourraud PA; Nantes Université, Centrale Nantes, CHU Nantes, Inserm, Center for Research in Transplantation and Translational Immunology, UMR 1064, ITUN, Nantes, France., Magnan A; Pneumology, Adult Cystic Fibrosis Center and Lung Transplantation Department Hôpital Foch, Suresnes, Université de Versailles Saint Quentin Paris-Saclay, INRAe UMR 0892, Paris Transplant Group, Paris, France., Lair D; Nantes Université, Centrale Nantes, CHU Nantes, Inserm, Center for Research in Transplantation and Translational Immunology, UMR 1064, ITUN, Nantes, France., Berthelot L; Nantes Université, Centrale Nantes, CHU Nantes, Inserm, Center for Research in Transplantation and Translational Immunology, UMR 1064, ITUN, Nantes, France., Südholt M; IMT Atlantique - DAPI - Département Automatique, Productique et Informatique, Nantes, France; LS2N - STACK - Software Stack for Massively Geo-Distributed Infrastructures, Nantes, France., Vince N; Nantes Université, Centrale Nantes, CHU Nantes, Inserm, Center for Research in Transplantation and Translational Immunology, UMR 1064, ITUN, Nantes, France., Tissot A; Nantes Université, Centrale Nantes, CHU Nantes, Inserm, Center for Research in Transplantation and Translational Immunology, UMR 1064, ITUN, Nantes, France; CHU Nantes, Nantes Université, Service de Pneumologie, Institut du thorax, F-44000 Nantes, France., Limou S; Nantes Université, Centrale Nantes, CHU Nantes, Inserm, Center for Research in Transplantation and Translational Immunology, UMR 1064, ITUN, Nantes, France. Electronic address: sophie.limou@univ-nantes.fr.
Corporate Authors: COLT consortium
Source: The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation [J Heart Lung Transplant] 2026 Mar 19. Date of Electronic Publication: 2026 Mar 19.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 9102703 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1557-3117 (Electronic) Linking ISSN: 10532498 NLM ISO Abbreviation: J Heart Lung Transplant Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Genome-wide association study reveals two novel genetic loci associated with chronic lung allograft dysfunction.
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  Data: <searchLink fieldCode="AU" term="%22Brocard+S%22">Brocard S</searchLink>; Nantes Université, Centrale Nantes, CHU Nantes, Inserm, Center for Research in Transplantation and Translational Immunology, UMR 1064, ITUN, Nantes, France; IMT Atlantique - DAPI - Département Automatique, Productique et Informatique, Nantes, France.<br /><searchLink fieldCode="AU" term="%22Mauduit+V%22">Mauduit V</searchLink>; Nantes Université, Centrale Nantes, CHU Nantes, Inserm, Center for Research in Transplantation and Translational Immunology, UMR 1064, ITUN, Nantes, France.<br /><searchLink fieldCode="AU" term="%22Morin+M%22">Morin M</searchLink>; Nantes Université, Centrale Nantes, CHU Nantes, Inserm, Center for Research in Transplantation and Translational Immunology, UMR 1064, ITUN, Nantes, France.<br /><searchLink fieldCode="AU" term="%22Boussamet+L%22">Boussamet L</searchLink>; Nantes Université, Centrale Nantes, CHU Nantes, Inserm, Center for Research in Transplantation and Translational Immunology, UMR 1064, ITUN, Nantes, France.<br /><searchLink fieldCode="AU" term="%22Silva+NDSB%22">Silva NDSB</searchLink>; Nantes Université, Centrale Nantes, CHU Nantes, Inserm, Center for Research in Transplantation and Translational Immunology, UMR 1064, ITUN, Nantes, France; São Paulo State University, Molecular Genetics and Bioinformatics Laboratory, School of Medicine, Botucatu, State of São Paulo, Brazil.<br /><searchLink fieldCode="AU" term="%22Durand+A%22">Durand A</searchLink>; Nantes Université, Centrale Nantes, CHU Nantes, Inserm, Center for Research in Transplantation and Translational Immunology, UMR 1064, ITUN, Nantes, France.<br /><searchLink fieldCode="AU" term="%22Halitim+P%22">Halitim P</searchLink>; Nantes Université, Centrale Nantes, CHU Nantes, Inserm, Center for Research in Transplantation and Translational Immunology, UMR 1064, ITUN, Nantes, France.<br /><searchLink fieldCode="AU" term="%22Renaud-Picard+B%22">Renaud-Picard B</searchLink>; Department of Respiratory Medicine and Strasbourg Lung Transplant Program, Hôpitaux Universitaires de Strasbourg, Strasbourg, France; Université de Strasbourg, Inserm UMR 1260, Strasbourg, France.<br /><searchLink fieldCode="AU" term="%22Coiffard+B%22">Coiffard B</searchLink>; Aix Marseille Univ, Department of Respiratory Medicine and Lung Transplantation, APHM, Hôpital Nord, Marseille, France.<br /><searchLink fieldCode="AU" term="%22Demant+X%22">Demant X</searchLink>; Service de Pneumologie, Centre Hospitalier Universitaire de Bordeaux, Pessac, France.<br /><searchLink fieldCode="AU" term="%22Falque+L%22">Falque L</searchLink>; Service Hospitalier Universitaire de Pneumologie et Physiologie, CHU Grenoble Alpes, Pôle Thorax et Vaisseaux, Grenoble, France.<br /><searchLink fieldCode="AU" term="%22Le+Pavec+J%22">Le Pavec J</searchLink>; Service de Pneumologie et Transplantation Pulmonaire, Groupe hospitalier Marie-Lannelongue -Saint Joseph, Le Plessis-Robinson, Université Paris-Saclay, Le Kremlin BicÊtre, UMR_S 999, Université Paris-Sud, INSERM, France.<br /><searchLink fieldCode="AU" term="%22Roux+A%22">Roux A</searchLink>; Pneumology, Adult Cystic Fibrosis Center and Lung Transplantation Department Hôpital Foch, Suresnes, Université de Versailles Saint Quentin Paris-Saclay, INRAe UMR 0892, Paris Transplant Group, Paris, France.<br /><searchLink fieldCode="AU" term="%22Villeneuve+T%22">Villeneuve T</searchLink>; CHU Toulouse, Service de Pneumologie, Université Toulouse III-Paul Sabatier, Toulouse, France.<br /><searchLink fieldCode="AU" term="%22Knoop+C%22">Knoop C</searchLink>; Service de Pneumologie, CHU Erasme, Bruxelles, Belgium.<br /><searchLink fieldCode="AU" term="%22Merveilleux+C%22">Merveilleux C</searchLink>; Université de Lyon, Université Lyon 1, PSL, EPHE, INRAE, IVPC, hospices civils de Lyon, groupement hospitalier est, service de pneumologie, Orphalung, RESPIFIL, Lyon, France.<br /><searchLink fieldCode="AU" term="%22Salpin+M%22">Salpin M</searchLink>; APHP Nord-Université Paris Cité, Hôpital Bichat, Service de Pneumologie B et Transplantation Pulmonaire, Université Paris Cité, PHERE UMRS 1152, Paris, France.<br /><searchLink fieldCode="AU" term="%22Carlier+N%22">Carlier N</searchLink>; APHP, Service de Pneumologie, Hôpital Cochin, Paris, France.<br /><searchLink fieldCode="AU" term="%22Gourraud+PA%22">Gourraud PA</searchLink>; Nantes Université, Centrale Nantes, CHU Nantes, Inserm, Center for Research in Transplantation and Translational Immunology, UMR 1064, ITUN, Nantes, France.<br /><searchLink fieldCode="AU" term="%22Magnan+A%22">Magnan A</searchLink>; Pneumology, Adult Cystic Fibrosis Center and Lung Transplantation Department Hôpital Foch, Suresnes, Université de Versailles Saint Quentin Paris-Saclay, INRAe UMR 0892, Paris Transplant Group, Paris, France.<br /><searchLink fieldCode="AU" term="%22Lair+D%22">Lair D</searchLink>; Nantes Université, Centrale Nantes, CHU Nantes, Inserm, Center for Research in Transplantation and Translational Immunology, UMR 1064, ITUN, Nantes, France.<br /><searchLink fieldCode="AU" term="%22Berthelot+L%22">Berthelot L</searchLink>; Nantes Université, Centrale Nantes, CHU Nantes, Inserm, Center for Research in Transplantation and Translational Immunology, UMR 1064, ITUN, Nantes, France.<br /><searchLink fieldCode="AU" term="%22Südholt+M%22">Südholt M</searchLink>; IMT Atlantique - DAPI - Département Automatique, Productique et Informatique, Nantes, France; LS2N - STACK - Software Stack for Massively Geo-Distributed Infrastructures, Nantes, France.<br /><searchLink fieldCode="AU" term="%22Vince+N%22">Vince N</searchLink>; Nantes Université, Centrale Nantes, CHU Nantes, Inserm, Center for Research in Transplantation and Translational Immunology, UMR 1064, ITUN, Nantes, France.<br /><searchLink fieldCode="AU" term="%22Tissot+A%22">Tissot A</searchLink>; Nantes Université, Centrale Nantes, CHU Nantes, Inserm, Center for Research in Transplantation and Translational Immunology, UMR 1064, ITUN, Nantes, France; CHU Nantes, Nantes Université, Service de Pneumologie, Institut du thorax, F-44000 Nantes, France.<br /><searchLink fieldCode="AU" term="%22Limou+S%22">Limou S</searchLink>; Nantes Université, Centrale Nantes, CHU Nantes, Inserm, Center for Research in Transplantation and Translational Immunology, UMR 1064, ITUN, Nantes, France. Electronic address: sophie.limou@univ-nantes.fr.
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