Dual-mechanistic regulation of podocyte pyroptosis in lupus nephritis by the AP-1 complex: transcriptional activation of NLRP3 and lactate-mediated ubiquitination inhibition.
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| Title: | Dual-mechanistic regulation of podocyte pyroptosis in lupus nephritis by the AP-1 complex: transcriptional activation of NLRP3 and lactate-mediated ubiquitination inhibition. |
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| Authors: | Chen PL; Department of Pathophysiology, Guizhou Medical University, Guiyang, China.; Guizhou Provincial Key Laboratory of Pathogenesis and Prevention of Common Chronic Diseases, Guizhou Medical University, Guiyang, China., Zhou QM; School of Nursing, Guizhou Medical University, Guiyang, China.; Guizhou Provincial Key Laboratory of Pathogenesis and Prevention of Common Chronic Diseases, Guizhou Medical University, Guiyang, China., Cui DL; School of Basic Medical Sciences, Qujing University of Medicine & Health Sciences, Qujing, China., Li XY; Department of Rheumatology and Nephrology, Beijing Jishuitan Hospital Guizhou Hospital, Guiyang, China., An XM; Department of Pathophysiology, Guizhou Medical University, Guiyang, China.; Guizhou Provincial Key Laboratory of Pathogenesis and Prevention of Common Chronic Diseases, Guizhou Medical University, Guiyang, China., Zhao F; Department of Pathophysiology, Guizhou Medical University, Guiyang, China.; Guizhou Provincial Key Laboratory of Pathogenesis and Prevention of Common Chronic Diseases, Guizhou Medical University, Guiyang, China., He S; School of Nursing, Guizhou Medical University, Guiyang, China.; Guizhou Provincial Key Laboratory of Pathogenesis and Prevention of Common Chronic Diseases, Guizhou Medical University, Guiyang, China., Tian XX; School of Nursing, Guizhou Medical University, Guiyang, China.; Guizhou Provincial Key Laboratory of Pathogenesis and Prevention of Common Chronic Diseases, Guizhou Medical University, Guiyang, China., Luo YQ; Department of Pathophysiology, Guizhou Medical University, Guiyang, China.; Guizhou Provincial Key Laboratory of Pathogenesis and Prevention of Common Chronic Diseases, Guizhou Medical University, Guiyang, China., Li LJ; School of Nursing, Guizhou Medical University, Guiyang, China.; Guizhou Provincial Key Laboratory of Pathogenesis and Prevention of Common Chronic Diseases, Guizhou Medical University, Guiyang, China., Wang TT; Department of Pathophysiology, Guizhou Medical University, Guiyang, China.; Guizhou Provincial Key Laboratory of Pathogenesis and Prevention of Common Chronic Diseases, Guizhou Medical University, Guiyang, China., Chen WY; Department of Pathophysiology, Guizhou Medical University, Guiyang, China.; Guizhou Provincial Key Laboratory of Pathogenesis and Prevention of Common Chronic Diseases, Guizhou Medical University, Guiyang, China., Chen L; School of Nursing, Guizhou Medical University, Guiyang, China.; Guizhou Provincial Key Laboratory of Pathogenesis and Prevention of Common Chronic Diseases, Guizhou Medical University, Guiyang, China., Zhou XR; School of Nursing, Guizhou Medical University, Guiyang, China.; Guizhou Provincial Key Laboratory of Pathogenesis and Prevention of Common Chronic Diseases, Guizhou Medical University, Guiyang, China., Cheng XY; Department of Pathophysiology, Guizhou Medical University, Guiyang, China.; Guizhou Provincial Key Laboratory of Pathogenesis and Prevention of Common Chronic Diseases, Guizhou Medical University, Guiyang, China., Zou HM; School of Nursing, Guizhou Medical University, Guiyang, China. huimeizou@yeah.net.; Guizhou Provincial Key Laboratory of Pathogenesis and Prevention of Common Chronic Diseases, Guizhou Medical University, Guiyang, China. huimeizou@yeah.net., Guo B; Department of Pathophysiology, Guizhou Medical University, Guiyang, China. guobingbs@126.com.; Guizhou Provincial Key Laboratory of Pathogenesis and Prevention of Common Chronic Diseases, Guizhou Medical University, Guiyang, China. guobingbs@126.com., Zhang F; Department of Pathophysiology, Guizhou Medical University, Guiyang, China. zfan1985@yeah.net.; Guizhou Provincial Key Laboratory of Pathogenesis and Prevention of Common Chronic Diseases, Guizhou Medical University, Guiyang, China. zfan1985@yeah.net. |
| Source: | Cell communication and signaling : CCS [Cell Commun Signal] 2026 Mar 21; Vol. 24 (1). Date of Electronic Publication: 2026 Mar 21. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: BioMed Central Country of Publication: England NLM ID: 101170464 Publication Model: Electronic Cited Medium: Internet ISSN: 1478-811X (Electronic) Linking ISSN: 1478811X NLM ISO Abbreviation: Cell Commun Signal Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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