Single-cell sequencing reveals metabolic reprogramming and immune regulation underlie the maintenance of teleost granulomas.

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Title: Single-cell sequencing reveals metabolic reprogramming and immune regulation underlie the maintenance of teleost granulomas.
Authors: Zhou ZY; Hainan Institute of Northwest A&F University, Sanya, Hainan, 572024, China; College of Animal Science and Technology, Northwest A&F University, Xinong Road 22nd, Yangling, Shaanxi, 712100, China., Jian ZR; Hainan Institute of Northwest A&F University, Sanya, Hainan, 572024, China; College of Animal Science and Technology, Northwest A&F University, Xinong Road 22nd, Yangling, Shaanxi, 712100, China., Gu JL; Hainan Institute of Northwest A&F University, Sanya, Hainan, 572024, China; College of Animal Science and Technology, Northwest A&F University, Xinong Road 22nd, Yangling, Shaanxi, 712100, China., Jiang XY; Hainan Institute of Northwest A&F University, Sanya, Hainan, 572024, China; College of Animal Science and Technology, Northwest A&F University, Xinong Road 22nd, Yangling, Shaanxi, 712100, China., He J; Chengdu Lilai Biotechnology Co., Ltd., Chengdu, Sichuan, 610000, China., Gao YC; Hainan Institute of Northwest A&F University, Sanya, Hainan, 572024, China; College of Animal Science and Technology, Northwest A&F University, Xinong Road 22nd, Yangling, Shaanxi, 712100, China., Lian S; Hainan Institute of Northwest A&F University, Sanya, Hainan, 572024, China; College of Animal Science and Technology, Northwest A&F University, Xinong Road 22nd, Yangling, Shaanxi, 712100, China., Bai SJ; Hainan Institute of Northwest A&F University, Sanya, Hainan, 572024, China; College of Animal Science and Technology, Northwest A&F University, Xinong Road 22nd, Yangling, Shaanxi, 712100, China., Lu CW; Hainan Institute of Northwest A&F University, Sanya, Hainan, 572024, China; College of Animal Science and Technology, Northwest A&F University, Xinong Road 22nd, Yangling, Shaanxi, 712100, China., Kuang LF; Hainan Institute of Northwest A&F University, Sanya, Hainan, 572024, China; College of Animal Science and Technology, Northwest A&F University, Xinong Road 22nd, Yangling, Shaanxi, 712100, China., Liu MZ; Guangxi Key Laboratory of Aquatic Biotechnology and Modern Ecological Aquaculture, Guangxi Academy of Sciences, Nanning, Guangxi, 530007, China., Li PF; Guangxi Key Laboratory of Aquatic Biotechnology and Modern Ecological Aquaculture, Guangxi Academy of Sciences, Nanning, Guangxi, 530007, China., Yu Q; Guangxi Key Laboratory of Aquatic Biotechnology and Modern Ecological Aquaculture, Guangxi Academy of Sciences, Nanning, Guangxi, 530007, China., Wang EL; Hainan Institute of Northwest A&F University, Sanya, Hainan, 572024, China; College of Animal Science and Technology, Northwest A&F University, Xinong Road 22nd, Yangling, Shaanxi, 712100, China., Wang GX; Hainan Institute of Northwest A&F University, Sanya, Hainan, 572024, China; College of Animal Science and Technology, Northwest A&F University, Xinong Road 22nd, Yangling, Shaanxi, 712100, China., Ling F; Hainan Institute of Northwest A&F University, Sanya, Hainan, 572024, China; College of Animal Science and Technology, Northwest A&F University, Xinong Road 22nd, Yangling, Shaanxi, 712100, China. Electronic address: feiling@nwsuaf.edu.cn., Galindo-Villegas J; Department of Genomics, Faculty of Biosciences and Aquaculture, Nord University, Bodø, 8049, Norway. Electronic address: jorge.galindo-villegas@nord.no., Liu T; Hainan Institute of Northwest A&F University, Sanya, Hainan, 572024, China; College of Animal Science and Technology, Northwest A&F University, Xinong Road 22nd, Yangling, Shaanxi, 712100, China. Electronic address: liutao_fish@nwafu.edu.cn.
Source: Fish & shellfish immunology [Fish Shellfish Immunol] 2026 Jun; Vol. 173, pp. 111287. Date of Electronic Publication: 2026 Mar 20.
Publication Type: Journal Article
Journal Info: Publisher: Academic Press Country of Publication: England NLM ID: 9505220 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1095-9947 (Electronic) Linking ISSN: 10504648 NLM ISO Abbreviation: Fish Shellfish Immunol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Single-cell sequencing reveals metabolic reprogramming and immune regulation underlie the maintenance of teleost granulomas.
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  Data: <searchLink fieldCode="AU" term="%22Zhou+ZY%22">Zhou ZY</searchLink>; Hainan Institute of Northwest A&F University, Sanya, Hainan, 572024, China; College of Animal Science and Technology, Northwest A&F University, Xinong Road 22nd, Yangling, Shaanxi, 712100, China.<br /><searchLink fieldCode="AU" term="%22Jian+ZR%22">Jian ZR</searchLink>; Hainan Institute of Northwest A&F University, Sanya, Hainan, 572024, China; College of Animal Science and Technology, Northwest A&F University, Xinong Road 22nd, Yangling, Shaanxi, 712100, China.<br /><searchLink fieldCode="AU" term="%22Gu+JL%22">Gu JL</searchLink>; Hainan Institute of Northwest A&F University, Sanya, Hainan, 572024, China; College of Animal Science and Technology, Northwest A&F University, Xinong Road 22nd, Yangling, Shaanxi, 712100, China.<br /><searchLink fieldCode="AU" term="%22Jiang+XY%22">Jiang XY</searchLink>; Hainan Institute of Northwest A&F University, Sanya, Hainan, 572024, China; College of Animal Science and Technology, Northwest A&F University, Xinong Road 22nd, Yangling, Shaanxi, 712100, China.<br /><searchLink fieldCode="AU" term="%22He+J%22">He J</searchLink>; Chengdu Lilai Biotechnology Co., Ltd., Chengdu, Sichuan, 610000, China.<br /><searchLink fieldCode="AU" term="%22Gao+YC%22">Gao YC</searchLink>; Hainan Institute of Northwest A&F University, Sanya, Hainan, 572024, China; College of Animal Science and Technology, Northwest A&F University, Xinong Road 22nd, Yangling, Shaanxi, 712100, China.<br /><searchLink fieldCode="AU" term="%22Lian+S%22">Lian S</searchLink>; Hainan Institute of Northwest A&F University, Sanya, Hainan, 572024, China; College of Animal Science and Technology, Northwest A&F University, Xinong Road 22nd, Yangling, Shaanxi, 712100, China.<br /><searchLink fieldCode="AU" term="%22Bai+SJ%22">Bai SJ</searchLink>; Hainan Institute of Northwest A&F University, Sanya, Hainan, 572024, China; College of Animal Science and Technology, Northwest A&F University, Xinong Road 22nd, Yangling, Shaanxi, 712100, China.<br /><searchLink fieldCode="AU" term="%22Lu+CW%22">Lu CW</searchLink>; Hainan Institute of Northwest A&F University, Sanya, Hainan, 572024, China; College of Animal Science and Technology, Northwest A&F University, Xinong Road 22nd, Yangling, Shaanxi, 712100, China.<br /><searchLink fieldCode="AU" term="%22Kuang+LF%22">Kuang LF</searchLink>; Hainan Institute of Northwest A&F University, Sanya, Hainan, 572024, China; College of Animal Science and Technology, Northwest A&F University, Xinong Road 22nd, Yangling, Shaanxi, 712100, China.<br /><searchLink fieldCode="AU" term="%22Liu+MZ%22">Liu MZ</searchLink>; Guangxi Key Laboratory of Aquatic Biotechnology and Modern Ecological Aquaculture, Guangxi Academy of Sciences, Nanning, Guangxi, 530007, China.<br /><searchLink fieldCode="AU" term="%22Li+PF%22">Li PF</searchLink>; Guangxi Key Laboratory of Aquatic Biotechnology and Modern Ecological Aquaculture, Guangxi Academy of Sciences, Nanning, Guangxi, 530007, China.<br /><searchLink fieldCode="AU" term="%22Yu+Q%22">Yu Q</searchLink>; Guangxi Key Laboratory of Aquatic Biotechnology and Modern Ecological Aquaculture, Guangxi Academy of Sciences, Nanning, Guangxi, 530007, China.<br /><searchLink fieldCode="AU" term="%22Wang+EL%22">Wang EL</searchLink>; Hainan Institute of Northwest A&F University, Sanya, Hainan, 572024, China; College of Animal Science and Technology, Northwest A&F University, Xinong Road 22nd, Yangling, Shaanxi, 712100, China.<br /><searchLink fieldCode="AU" term="%22Wang+GX%22">Wang GX</searchLink>; Hainan Institute of Northwest A&F University, Sanya, Hainan, 572024, China; College of Animal Science and Technology, Northwest A&F University, Xinong Road 22nd, Yangling, Shaanxi, 712100, China.<br /><searchLink fieldCode="AU" term="%22Ling+F%22">Ling F</searchLink>; Hainan Institute of Northwest A&F University, Sanya, Hainan, 572024, China; College of Animal Science and Technology, Northwest A&F University, Xinong Road 22nd, Yangling, Shaanxi, 712100, China. Electronic address: feiling@nwsuaf.edu.cn.<br /><searchLink fieldCode="AU" term="%22Galindo-Villegas+J%22">Galindo-Villegas J</searchLink>; Department of Genomics, Faculty of Biosciences and Aquaculture, Nord University, Bodø, 8049, Norway. Electronic address: jorge.galindo-villegas@nord.no.<br /><searchLink fieldCode="AU" term="%22Liu+T%22">Liu T</searchLink>; Hainan Institute of Northwest A&F University, Sanya, Hainan, 572024, China; College of Animal Science and Technology, Northwest A&F University, Xinong Road 22nd, Yangling, Shaanxi, 712100, China. Electronic address: liutao_fish@nwafu.edu.cn.
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  Data: <searchLink fieldCode="JN" term="%229505220%22">Fish & shellfish immunology</searchLink> [Fish Shellfish Immunol] 2026 Jun; Vol. 173, pp. 111287. <i>Date of Electronic Publication: </i>2026 Mar 20.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Academic+Press%22">Academic Press </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>9505220 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1095-9947 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2210504648%22">10504648 </searchLink><i>NLM ISO Abbreviation: </i>Fish Shellfish Immunol <i>Subsets: </i>MEDLINE
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              Text: 2026 Jun
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