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C4orf3 Regulates HIF-1α Degradation Under Hypoxic Conditions and Contributes to the Malignant Phenotype in Small Cell Lung Cancer.

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Title: C4orf3 Regulates HIF-1α Degradation Under Hypoxic Conditions and Contributes to the Malignant Phenotype in Small Cell Lung Cancer.
Authors: Sakanashi K; Department of Surgery and Oncology, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka 812-8582, Japan; Department of Surgery and Oncology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan., Onishi H; Pancreatobiliary Surgery/ Kidney and Pancreas Transplantation, Kyushu University Hospital, 3-1-1 Maidashi, Higashi-ku, Fukuoka 812-8582, Japan., Iwamoto N; Department of Surgery and Oncology, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka 812-8582, Japan; Department of Surgery and Oncology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan., Nakanishi Y; Department of Surgery and Oncology, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka 812-8582, Japan; Department of Surgery and Oncology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan., Itoyama S; Department of Otorhinolaryngology Graduate School of Medical Sciences Kyushu University Fukuoka, Japan., Masuda S; Department of Otorhinolaryngology Graduate School of Medical Sciences Kyushu University Fukuoka, Japan., Ozono K; Department of Respiratory Surgery, Hamanomachi Hospital, Fukuoka, Japan., Yanai K; Yakuin Internal Medicine and Cardiology Clinic, Fukuoka, Japan., Nakamura K; Department of Respiratory Surgery, Japan Community Health Care Organisation, Kyushu Hospital, Kitakyushu, Japan., Nagami M; Fukuoka General Cancer Clinic, Fukuoka, Japan., Nishiyama K; Department of Pathology, Japanese Red Cross Fukuoka Hospital, Fukuoka, Japan., Kojima M; Department of Surgery and Oncology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan; Japanese Red Cross, Fukuoka Hospital, Fukuoka, Japan., Oda Y; Department of Anatomical Pathology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan., Nakamura M; Department of Surgery and Oncology, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka 812-8582, Japan; Department of Surgery and Oncology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.
Source: Journal of Cancer [J Cancer] 2026 Jan 23; Vol. 17 (3), pp. 457-468. Date of Electronic Publication: 2026 Jan 23 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Ivyspring International Publisher Country of Publication: Australia NLM ID: 101535920 Publication Model: eCollection Cited Medium: Print ISSN: 1837-9664 (Print) Linking ISSN: 18379664 NLM ISO Abbreviation: J Cancer Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: C4orf3 Regulates HIF-1α Degradation Under Hypoxic Conditions and Contributes to the Malignant Phenotype in Small Cell Lung Cancer.
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  Data: <searchLink fieldCode="AU" term="%22Sakanashi+K%22">Sakanashi K</searchLink>; Department of Surgery and Oncology, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka 812-8582, Japan; Department of Surgery and Oncology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.<br /><searchLink fieldCode="AU" term="%22Onishi+H%22">Onishi H</searchLink>; Pancreatobiliary Surgery/ Kidney and Pancreas Transplantation, Kyushu University Hospital, 3-1-1 Maidashi, Higashi-ku, Fukuoka 812-8582, Japan.<br /><searchLink fieldCode="AU" term="%22Iwamoto+N%22">Iwamoto N</searchLink>; Department of Surgery and Oncology, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka 812-8582, Japan; Department of Surgery and Oncology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.<br /><searchLink fieldCode="AU" term="%22Nakanishi+Y%22">Nakanishi Y</searchLink>; Department of Surgery and Oncology, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka 812-8582, Japan; Department of Surgery and Oncology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.<br /><searchLink fieldCode="AU" term="%22Itoyama+S%22">Itoyama S</searchLink>; Department of Otorhinolaryngology Graduate School of Medical Sciences Kyushu University Fukuoka, Japan.<br /><searchLink fieldCode="AU" term="%22Masuda+S%22">Masuda S</searchLink>; Department of Otorhinolaryngology Graduate School of Medical Sciences Kyushu University Fukuoka, Japan.<br /><searchLink fieldCode="AU" term="%22Ozono+K%22">Ozono K</searchLink>; Department of Respiratory Surgery, Hamanomachi Hospital, Fukuoka, Japan.<br /><searchLink fieldCode="AU" term="%22Yanai+K%22">Yanai K</searchLink>; Yakuin Internal Medicine and Cardiology Clinic, Fukuoka, Japan.<br /><searchLink fieldCode="AU" term="%22Nakamura+K%22">Nakamura K</searchLink>; Department of Respiratory Surgery, Japan Community Health Care Organisation, Kyushu Hospital, Kitakyushu, Japan.<br /><searchLink fieldCode="AU" term="%22Nagami+M%22">Nagami M</searchLink>; Fukuoka General Cancer Clinic, Fukuoka, Japan.<br /><searchLink fieldCode="AU" term="%22Nishiyama+K%22">Nishiyama K</searchLink>; Department of Pathology, Japanese Red Cross Fukuoka Hospital, Fukuoka, Japan.<br /><searchLink fieldCode="AU" term="%22Kojima+M%22">Kojima M</searchLink>; Department of Surgery and Oncology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan; Japanese Red Cross, Fukuoka Hospital, Fukuoka, Japan.<br /><searchLink fieldCode="AU" term="%22Oda+Y%22">Oda Y</searchLink>; Department of Anatomical Pathology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.<br /><searchLink fieldCode="AU" term="%22Nakamura+M%22">Nakamura M</searchLink>; Department of Surgery and Oncology, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka 812-8582, Japan; Department of Surgery and Oncology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.
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  Data: <searchLink fieldCode="JN" term="%22101535920%22">Journal of Cancer</searchLink> [J Cancer] 2026 Jan 23; Vol. 17 (3), pp. 457-468. <i>Date of Electronic Publication: </i>2026 Jan 23 (<i>Print Publication: </i>2026).
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Ivyspring+International+Publisher%22">Ivyspring International Publisher </searchLink><i>Country of Publication: </i>Australia <i>NLM ID: </i>101535920 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Print <i>ISSN: </i>1837-9664 (Print) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2218379664%22">18379664 </searchLink><i>NLM ISO Abbreviation: </i>J Cancer <i>Subsets: </i>PubMed not MEDLINE
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