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Five tenets for advancing evidence-based precision medicine.

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Title: Five tenets for advancing evidence-based precision medicine.
Authors: Coral DE; Genetic & Molecular Epidemiology Unit, Department of Clinical Sciences, Lund University, Helsingborg, Sweden. daniel.coral@med.lu.se.; Diabetic Complications Unit, Department of Clinical Sciences, Lund University, Malmo, Sweden. daniel.coral@med.lu.se., Sargent JL; Heidelberg Institute of Global Health, Heidelberg University, Heidelberg, Germany.; School of Public Health, Imperial College London, London, UK., Carrasco-Zanini J; Precision Healthcare University Research Institute, Queen Mary University of London, London, UK., Coral LM; Genetic & Molecular Epidemiology Unit, Department of Clinical Sciences, Lund University, Helsingborg, Sweden., Deutsch AJ; Diabetes Unit and Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA.; Programs in Metabolism and Medical & Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Medicine, Harvard Medical School, Boston, MA, USA., Udler MS; Diabetes Unit and Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA.; Programs in Metabolism and Medical & Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Medicine, Harvard Medical School, Boston, MA, USA., Giordano GN; Genetic & Molecular Epidemiology Unit, Department of Clinical Sciences, Lund University, Helsingborg, Sweden., Pare G; McMaster University, Hamilton, Ontario, Canada., Pearson ER; School of Medicine, University of Dundee, Dundee, Scotland., van Smeden M; Julius Center for Health Sciences and Primary Care, Department of Data Science and Biostatistics, University Medical Center Utrecht, University of Utrecht, Utrecht, The Netherlands., Franks PW; Genetic & Molecular Epidemiology Unit, Department of Clinical Sciences, Lund University, Helsingborg, Sweden. paul.franks@med.lu.se.; Precision Healthcare University Research Institute, Queen Mary University of London, London, UK. paul.franks@med.lu.se.
Source: Nature medicine [Nat Med] 2026 Apr; Vol. 32 (4), pp. 1211-1222. Date of Electronic Publication: 2026 Mar 23.
Publication Type: Journal Article; Review
Journal Info: Publisher: Nature Publishing Company Country of Publication: United States NLM ID: 9502015 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1546-170X (Electronic) Linking ISSN: 10788956 NLM ISO Abbreviation: Nat Med Subsets: MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Coral+DE%22">Coral DE</searchLink>; Genetic & Molecular Epidemiology Unit, Department of Clinical Sciences, Lund University, Helsingborg, Sweden. daniel.coral@med.lu.se.; Diabetic Complications Unit, Department of Clinical Sciences, Lund University, Malmo, Sweden. daniel.coral@med.lu.se.<br /><searchLink fieldCode="AU" term="%22Sargent+JL%22">Sargent JL</searchLink>; Heidelberg Institute of Global Health, Heidelberg University, Heidelberg, Germany.; School of Public Health, Imperial College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Carrasco-Zanini+J%22">Carrasco-Zanini J</searchLink>; Precision Healthcare University Research Institute, Queen Mary University of London, London, UK.<br /><searchLink fieldCode="AU" term="%22Coral+LM%22">Coral LM</searchLink>; Genetic & Molecular Epidemiology Unit, Department of Clinical Sciences, Lund University, Helsingborg, Sweden.<br /><searchLink fieldCode="AU" term="%22Deutsch+AJ%22">Deutsch AJ</searchLink>; Diabetes Unit and Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA.; Programs in Metabolism and Medical & Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Medicine, Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Udler+MS%22">Udler MS</searchLink>; Diabetes Unit and Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA.; Programs in Metabolism and Medical & Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Medicine, Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Giordano+GN%22">Giordano GN</searchLink>; Genetic & Molecular Epidemiology Unit, Department of Clinical Sciences, Lund University, Helsingborg, Sweden.<br /><searchLink fieldCode="AU" term="%22Pare+G%22">Pare G</searchLink>; McMaster University, Hamilton, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Pearson+ER%22">Pearson ER</searchLink>; School of Medicine, University of Dundee, Dundee, Scotland.<br /><searchLink fieldCode="AU" term="%22van+Smeden+M%22">van Smeden M</searchLink>; Julius Center for Health Sciences and Primary Care, Department of Data Science and Biostatistics, University Medical Center Utrecht, University of Utrecht, Utrecht, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Franks+PW%22">Franks PW</searchLink>; Genetic & Molecular Epidemiology Unit, Department of Clinical Sciences, Lund University, Helsingborg, Sweden. paul.franks@med.lu.se.; Precision Healthcare University Research Institute, Queen Mary University of London, London, UK. paul.franks@med.lu.se.
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  Data: <searchLink fieldCode="JN" term="%229502015%22">Nature medicine</searchLink> [Nat Med] 2026 Apr; Vol. 32 (4), pp. 1211-1222. <i>Date of Electronic Publication: </i>2026 Mar 23.
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