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Biosensor-guided directed evolution of aldehyde dehydrogenase for improved adipic acid production from caprolactone.

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Title: Biosensor-guided directed evolution of aldehyde dehydrogenase for improved adipic acid production from caprolactone.
Authors: Kim H; Synthetic Biology Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), 125, Gwahak-ro, Yuseong-gu, Daejeon, 34141, South Korea.; Center for Bio-Based Chemistry, Korea Research Institute of Chemical Technology (KRICT), 406-30, Jongga-Ro, Jung-Gu, Ulsan, 44429, South Korea.; School of Interdisciplinary Bioscience and Bioengineering, Pohang University of Science and Technology, 77 Cheongam-Ro, Nam-Gu, Pohang, Gyeongbuk, 37673, South Korea., Moon SY; Graduate School of Engineering Biology, Korea Advanced Institute of Science and Technology (KAIST), 91, Daehak-Ro, Yuseong-Gu, Daejeon, 34051, South Korea., Park JY; Center for Bio-Based Chemistry, Korea Research Institute of Chemical Technology (KRICT), 406-30, Jongga-Ro, Jung-Gu, Ulsan, 44429, South Korea., Baek SH; Center for Bio-Based Chemistry, Korea Research Institute of Chemical Technology (KRICT), 406-30, Jongga-Ro, Jung-Gu, Ulsan, 44429, South Korea., Sung BH; Synthetic Biology Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), 125, Gwahak-ro, Yuseong-gu, Daejeon, 34141, South Korea.; Korea Biofoundry, Korea Research Institute of Bioscience and Biotechnology (KRIBB), 125, Gwahak-ro, Yuseong-gu, Daejeon, 34141, South Korea., Lee JW; School of Interdisciplinary Bioscience and Bioengineering, Pohang University of Science and Technology, 77 Cheongam-Ro, Nam-Gu, Pohang, Gyeongbuk, 37673, South Korea. jeongwook@postech.ac.kr.; Department of Chemical Engineering, Pohang University of Science and Technology, 77 Cheongam-Ro, Nam-Gu, Pohang, Gyeongbuk, 37673, South Korea. jeongwook@postech.ac.kr., Lee JY; Graduate School of Engineering Biology, Korea Advanced Institute of Science and Technology (KAIST), 91, Daehak-Ro, Yuseong-Gu, Daejeon, 34051, South Korea. juyounglee@kaist.ac.kr.; Department of Biological Sciences, Korea Advanced Institute of Science and Technology (KAIST), 91, Daehak-Ro, Yuseong-Gu, Daejeon, 34051, South Korea. juyounglee@kaist.ac.kr., Noh MH; Synthetic Biology Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), 125, Gwahak-ro, Yuseong-gu, Daejeon, 34141, South Korea. mhnoh@kribb.re.kr.; Center for Bio-Based Chemistry, Korea Research Institute of Chemical Technology (KRICT), 406-30, Jongga-Ro, Jung-Gu, Ulsan, 44429, South Korea. mhnoh@kribb.re.kr.; Korea Biofoundry, Korea Research Institute of Bioscience and Biotechnology (KRIBB), 125, Gwahak-ro, Yuseong-gu, Daejeon, 34141, South Korea. mhnoh@kribb.re.kr.
Source: Journal of biological engineering [J Biol Eng] 2026 Mar 23; Vol. 20 (1). Date of Electronic Publication: 2026 Mar 23.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101306640 Publication Model: Electronic Cited Medium: Print ISSN: 1754-1611 (Print) Linking ISSN: 17541611 NLM ISO Abbreviation: J Biol Eng Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Biosensor-guided directed evolution of aldehyde dehydrogenase for improved adipic acid production from caprolactone.
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  Data: <searchLink fieldCode="AU" term="%22Kim+H%22">Kim H</searchLink>; Synthetic Biology Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), 125, Gwahak-ro, Yuseong-gu, Daejeon, 34141, South Korea.; Center for Bio-Based Chemistry, Korea Research Institute of Chemical Technology (KRICT), 406-30, Jongga-Ro, Jung-Gu, Ulsan, 44429, South Korea.; School of Interdisciplinary Bioscience and Bioengineering, Pohang University of Science and Technology, 77 Cheongam-Ro, Nam-Gu, Pohang, Gyeongbuk, 37673, South Korea.<br /><searchLink fieldCode="AU" term="%22Moon+SY%22">Moon SY</searchLink>; Graduate School of Engineering Biology, Korea Advanced Institute of Science and Technology (KAIST), 91, Daehak-Ro, Yuseong-Gu, Daejeon, 34051, South Korea.<br /><searchLink fieldCode="AU" term="%22Park+JY%22">Park JY</searchLink>; Center for Bio-Based Chemistry, Korea Research Institute of Chemical Technology (KRICT), 406-30, Jongga-Ro, Jung-Gu, Ulsan, 44429, South Korea.<br /><searchLink fieldCode="AU" term="%22Baek+SH%22">Baek SH</searchLink>; Center for Bio-Based Chemistry, Korea Research Institute of Chemical Technology (KRICT), 406-30, Jongga-Ro, Jung-Gu, Ulsan, 44429, South Korea.<br /><searchLink fieldCode="AU" term="%22Sung+BH%22">Sung BH</searchLink>; Synthetic Biology Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), 125, Gwahak-ro, Yuseong-gu, Daejeon, 34141, South Korea.; Korea Biofoundry, Korea Research Institute of Bioscience and Biotechnology (KRIBB), 125, Gwahak-ro, Yuseong-gu, Daejeon, 34141, South Korea.<br /><searchLink fieldCode="AU" term="%22Lee+JW%22">Lee JW</searchLink>; School of Interdisciplinary Bioscience and Bioengineering, Pohang University of Science and Technology, 77 Cheongam-Ro, Nam-Gu, Pohang, Gyeongbuk, 37673, South Korea. jeongwook@postech.ac.kr.; Department of Chemical Engineering, Pohang University of Science and Technology, 77 Cheongam-Ro, Nam-Gu, Pohang, Gyeongbuk, 37673, South Korea. jeongwook@postech.ac.kr.<br /><searchLink fieldCode="AU" term="%22Lee+JY%22">Lee JY</searchLink>; Graduate School of Engineering Biology, Korea Advanced Institute of Science and Technology (KAIST), 91, Daehak-Ro, Yuseong-Gu, Daejeon, 34051, South Korea. juyounglee@kaist.ac.kr.; Department of Biological Sciences, Korea Advanced Institute of Science and Technology (KAIST), 91, Daehak-Ro, Yuseong-Gu, Daejeon, 34051, South Korea. juyounglee@kaist.ac.kr.<br /><searchLink fieldCode="AU" term="%22Noh+MH%22">Noh MH</searchLink>; Synthetic Biology Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), 125, Gwahak-ro, Yuseong-gu, Daejeon, 34141, South Korea. mhnoh@kribb.re.kr.; Center for Bio-Based Chemistry, Korea Research Institute of Chemical Technology (KRICT), 406-30, Jongga-Ro, Jung-Gu, Ulsan, 44429, South Korea. mhnoh@kribb.re.kr.; Korea Biofoundry, Korea Research Institute of Bioscience and Biotechnology (KRIBB), 125, Gwahak-ro, Yuseong-gu, Daejeon, 34141, South Korea. mhnoh@kribb.re.kr.
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  Data: <searchLink fieldCode="JN" term="%22101306640%22">Journal of biological engineering</searchLink> [J Biol Eng] 2026 Mar 23; Vol. 20 (1). <i>Date of Electronic Publication: </i>2026 Mar 23.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22BioMed+Central%22">BioMed Central </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101306640 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Print <i>ISSN: </i>1754-1611 (Print) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2217541611%22">17541611 </searchLink><i>NLM ISO Abbreviation: </i>J Biol Eng <i>Subsets: </i>PubMed not MEDLINE
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        Value: 10.1186/s13036-026-00665-6
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            NameFull: Kim H
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              Text: 2026 Mar 23
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