Crude Extract and Phenol-Rich Fractions from Vernonia amygdalina Leaves Ameliorates Streptozotocin-Induced Type 1 Diabetes in Rats by Mitigating Hepatic Injury, Dyslipidemia, and Production of Oxido-Inflammatory Markers.

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Title: Crude Extract and Phenol-Rich Fractions from Vernonia amygdalina Leaves Ameliorates Streptozotocin-Induced Type 1 Diabetes in Rats by Mitigating Hepatic Injury, Dyslipidemia, and Production of Oxido-Inflammatory Markers.
Authors: Ajuwon OR; Redox Biology Research Laboratory, Department of Biochemistry, Federal University Oye-Ekiti, Oye-Ekiti P.M.B. 373, Ekiti State, Nigeria., Oladejo DR; Redox Biology Research Laboratory, Department of Biochemistry, Federal University Oye-Ekiti, Oye-Ekiti P.M.B. 373, Ekiti State, Nigeria., Adeoye AO; Biomembrane, Phytomedicine, and Drug Development Unit, Department of Biochemistry, Federal University Oye-Ekiti, Oye-Ekiti P.M.B. 373, Ekiti State, Nigeria., Falode JA; Biomembrane, Molecular Pharmacology, and Toxicology Laboratory, Department of Biochemistry, Federal University Oye-Ekiti, Oye-Ekiti P.M.B. 373, Ekiti State, Nigeria., Ajiboye BO; Phytomedicine and Molecular Toxicology Research Laboratory, Department of Biochemistry, Federal University Oye-Ekiti, Oye-Ekiti P.M.B. 373, Ekiti State, Nigeria., Osunsanmi FO; Biotechnology and Structural Biology (BSB) Group, Department of Biochemistry and Microbiology, University of Zululand, KwaDlangezwa 3886, South Africa., Oyinloye BE; Biotechnology and Structural Biology (BSB) Group, Department of Biochemistry and Microbiology, University of Zululand, KwaDlangezwa 3886, South Africa.; Institute for Drug Research and Development, Bogoro Research Centre, Afe Babalola University, Ado-Ekiti P.M.B. 5454, Ekiti State, Nigeria.; Phytomedicine, Biochemical Toxicology and Biotechnology Research Laboratories, Department of Biochemistry, College of Sciences, Afe Babalola University, Ado-Ekiti P.M.B. 5454, Ekiti State, Nigeria.
Source: Journal of xenobiotics [J Xenobiot] 2026 Mar 20; Vol. 16 (2). Date of Electronic Publication: 2026 Mar 20.
Publication Type: Journal Article
Journal Info: Publisher: MDPI AG Country of Publication: Switzerland NLM ID: 101701430 Publication Model: Electronic Cited Medium: Internet ISSN: 2039-4713 (Electronic) Linking ISSN: 20394705 NLM ISO Abbreviation: J Xenobiot Subsets: PubMed not MEDLINE
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  Data: Crude Extract and Phenol-Rich Fractions from Vernonia amygdalina Leaves Ameliorates Streptozotocin-Induced Type 1 Diabetes in Rats by Mitigating Hepatic Injury, Dyslipidemia, and Production of Oxido-Inflammatory Markers.
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  Data: <searchLink fieldCode="AU" term="%22Ajuwon+OR%22">Ajuwon OR</searchLink>; Redox Biology Research Laboratory, Department of Biochemistry, Federal University Oye-Ekiti, Oye-Ekiti P.M.B. 373, Ekiti State, Nigeria.<br /><searchLink fieldCode="AU" term="%22Oladejo+DR%22">Oladejo DR</searchLink>; Redox Biology Research Laboratory, Department of Biochemistry, Federal University Oye-Ekiti, Oye-Ekiti P.M.B. 373, Ekiti State, Nigeria.<br /><searchLink fieldCode="AU" term="%22Adeoye+AO%22">Adeoye AO</searchLink>; Biomembrane, Phytomedicine, and Drug Development Unit, Department of Biochemistry, Federal University Oye-Ekiti, Oye-Ekiti P.M.B. 373, Ekiti State, Nigeria.<br /><searchLink fieldCode="AU" term="%22Falode+JA%22">Falode JA</searchLink>; Biomembrane, Molecular Pharmacology, and Toxicology Laboratory, Department of Biochemistry, Federal University Oye-Ekiti, Oye-Ekiti P.M.B. 373, Ekiti State, Nigeria.<br /><searchLink fieldCode="AU" term="%22Ajiboye+BO%22">Ajiboye BO</searchLink>; Phytomedicine and Molecular Toxicology Research Laboratory, Department of Biochemistry, Federal University Oye-Ekiti, Oye-Ekiti P.M.B. 373, Ekiti State, Nigeria.<br /><searchLink fieldCode="AU" term="%22Osunsanmi+FO%22">Osunsanmi FO</searchLink>; Biotechnology and Structural Biology (BSB) Group, Department of Biochemistry and Microbiology, University of Zululand, KwaDlangezwa 3886, South Africa.<br /><searchLink fieldCode="AU" term="%22Oyinloye+BE%22">Oyinloye BE</searchLink>; Biotechnology and Structural Biology (BSB) Group, Department of Biochemistry and Microbiology, University of Zululand, KwaDlangezwa 3886, South Africa.; Institute for Drug Research and Development, Bogoro Research Centre, Afe Babalola University, Ado-Ekiti P.M.B. 5454, Ekiti State, Nigeria.; Phytomedicine, Biochemical Toxicology and Biotechnology Research Laboratories, Department of Biochemistry, College of Sciences, Afe Babalola University, Ado-Ekiti P.M.B. 5454, Ekiti State, Nigeria.
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  Data: <searchLink fieldCode="JN" term="%22101701430%22">Journal of xenobiotics</searchLink> [J Xenobiot] 2026 Mar 20; Vol. 16 (2). <i>Date of Electronic Publication: </i>2026 Mar 20.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22MDPI+AG%22">MDPI AG </searchLink><i>Country of Publication: </i>Switzerland <i>NLM ID: </i>101701430 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2039-4713 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2220394705%22">20394705 </searchLink><i>NLM ISO Abbreviation: </i>J Xenobiot <i>Subsets: </i>PubMed not MEDLINE
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              Text: 2026 Mar 20
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