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Real-world effectiveness of avelumab, pembrolizumab, and enfortumab vedotin in patients with advanced urothelial carcinoma with squamous differentiation (ARON-2EV).

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Title: Real-world effectiveness of avelumab, pembrolizumab, and enfortumab vedotin in patients with advanced urothelial carcinoma with squamous differentiation (ARON-2EV).
Authors: Mollica V; Medical Oncology, IRCCS Azienda Ospedaliero-Universitaria Di Bologna, Bologna, Italy., Massari F; Medical Oncology, IRCCS Azienda Ospedaliero-Universitaria Di Bologna, Bologna, Italy. francesco.massari8@unibo.it.; Department of Medical and Surgical Sciences (DIMEC), University of Bologna, Bologna, Italy. francesco.massari8@unibo.it., Fujita K; Department of Urology, Faculty of Medicine, Kindai University, Osaka, Japan., Giannatempo P; Dipartimento Di Oncologia Medica, Fondazione IRCCS Istituto Nazionale Dei Tumori, Milan, Italy., Grande E; Department of Medical Oncology, MD Anderson Cancer Center Madrid, Madrid, Spain., Büttner T; Department of Urology, University Hospital Bonn, Bonn, Germany., Bourlon MT; Department of Hemato-Oncology, Escuela de Medicina, Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran, Mexico City, Mexico-Universidad Panamericana, Mexico City, Mexico., Taha T; Royal Marsden NHS Foundation Trust, London, UK., Fukuokaya W; Department of Urology, Jikei University School of Medicine, Tokyo, Japan., Myint ZW; Division of Medical Oncology, Department of Internal Medicine, Markey Cancer Center, University of Kentucky, Lexington, KY, USA., Pichler R; Department of Urology, Comprehensive Cancer Center Innsbruck, Medical University of Innsbruck, Innsbruck, Austria., Binz K; Division of Medical Oncology, Department of Internal Medicine, University of Kansas Cancer Center, Kansas, USA., Molina-Cerrillo J; Department of Medical Oncology, Hospital Ramón y Cajal, Madrid, Spain., Kopecky J; Department of Clinical Oncology and Radiotherapy, University Hospital Hradec Kralove, Hradec Kralove, Czechia., de Liaño AG; Medical Oncology Department, CHU Insular-Materno Infantil, Las Palmas, Spain., Kucharz J; Department of Uro-Oncology, Maria Sklodowska-Curie National Research Institute of Oncology Warsaw, Warsaw, Poland., Fiala O; Department of Oncology and Radiotherapeutics, Faculty of Medicine and University Hospital in Pilsen, Charles University, Pilsen, Czech Republic.; Biomedical Center, Faculty of Medicine in Pilsen, Charles University, Pilsen, Czech Republic., Matrana MR; Department of Internal Medicine, Hematology/Oncology, Ochsner Medical Center, New Orleans, LA, USA., Kopp RM; Clinical Oncology, Sociedad de Oncología y Hematología del Cesar, Valledupar, Colombia., Di Civita MA; Department of Radiological, Oncological and Pathological Sciences, Policlinico Umberto I, University of Rome, Rome, Italy., Zgura A; Department of Obstetrics-Radiotherapy, Alexandru Trestioreanu Institute of Oncology, 'Carol Davila' University of Medicine and Pharmacy, Prof. Dr, Bucharest, Romania., Ansari J; Medical Oncology, Tawam Hospital, Al Ain, UAE., Kihnel R; Department of Internal Medicine, Hematology/Oncology, Ochsner Medical Center, New Orleans, LA, USA., De Felice F; Radiation Oncology, Department of Radiological, AOU Policlinico Umberto I, Oncological and Pathological Sciences, 'Sapienza' University of Rome, Rome, Italy., Angel M; Instituto Alexander Fleming, Ciudad De Buenos Aires, Argentina., Monteiro FSM; Latin American Cooperative Oncology Group-LACOG, Porto Alegre, Brazil.; Oncology and Hematology Department, Hospital Sírio Libanês, Brasília, Brazil., Soares A; Latin American Cooperative Oncology Group-LACOG, Porto Alegre, Brazil.; Oncology Unit, Hospital Israelita Albert Einstein, São Paulo, SP, Brazil., Urun Y; Department of Medical Oncology, Faculty of Medicine, Ankara University, 06620, Ankara, Turkey., Buti S; Medical Oncology Unit, University Hospital of Parma, Parma, Italy.; Department of Medicine and Surgery, University of Parma, Parma, Italy., Santini D; Department of Radiological, Oncological and Pathological Sciences, Policlinico Umberto I, University of Rome, Rome, Italy., Santoni M; Medical Oncology Unit, Macerata Hospital, Macerata, Italy.
Source: Cancer immunology, immunotherapy : CII [Cancer Immunol Immunother] 2026 Mar 24; Vol. 75 (4). Date of Electronic Publication: 2026 Mar 24.
Publication Type: Journal Article; Multicenter Study
Journal Info: Publisher: Springer Verlag Country of Publication: Germany NLM ID: 8605732 Publication Model: Electronic Cited Medium: Internet ISSN: 1432-0851 (Electronic) Linking ISSN: 03407004 NLM ISO Abbreviation: Cancer Immunol Immunother Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Real-world effectiveness of avelumab, pembrolizumab, and enfortumab vedotin in patients with advanced urothelial carcinoma with squamous differentiation (ARON-2EV).
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  Data: <searchLink fieldCode="AU" term="%22Mollica+V%22">Mollica V</searchLink>; Medical Oncology, IRCCS Azienda Ospedaliero-Universitaria Di Bologna, Bologna, Italy.<br /><searchLink fieldCode="AU" term="%22Massari+F%22">Massari F</searchLink>; Medical Oncology, IRCCS Azienda Ospedaliero-Universitaria Di Bologna, Bologna, Italy. francesco.massari8@unibo.it.; Department of Medical and Surgical Sciences (DIMEC), University of Bologna, Bologna, Italy. francesco.massari8@unibo.it.<br /><searchLink fieldCode="AU" term="%22Fujita+K%22">Fujita K</searchLink>; Department of Urology, Faculty of Medicine, Kindai University, Osaka, Japan.<br /><searchLink fieldCode="AU" term="%22Giannatempo+P%22">Giannatempo P</searchLink>; Dipartimento Di Oncologia Medica, Fondazione IRCCS Istituto Nazionale Dei Tumori, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Grande+E%22">Grande E</searchLink>; Department of Medical Oncology, MD Anderson Cancer Center Madrid, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Büttner+T%22">Büttner T</searchLink>; Department of Urology, University Hospital Bonn, Bonn, Germany.<br /><searchLink fieldCode="AU" term="%22Bourlon+MT%22">Bourlon MT</searchLink>; Department of Hemato-Oncology, Escuela de Medicina, Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran, Mexico City, Mexico-Universidad Panamericana, Mexico City, Mexico.<br /><searchLink fieldCode="AU" term="%22Taha+T%22">Taha T</searchLink>; Royal Marsden NHS Foundation Trust, London, UK.<br /><searchLink fieldCode="AU" term="%22Fukuokaya+W%22">Fukuokaya W</searchLink>; Department of Urology, Jikei University School of Medicine, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Myint+ZW%22">Myint ZW</searchLink>; Division of Medical Oncology, Department of Internal Medicine, Markey Cancer Center, University of Kentucky, Lexington, KY, USA.<br /><searchLink fieldCode="AU" term="%22Pichler+R%22">Pichler R</searchLink>; Department of Urology, Comprehensive Cancer Center Innsbruck, Medical University of Innsbruck, Innsbruck, Austria.<br /><searchLink fieldCode="AU" term="%22Binz+K%22">Binz K</searchLink>; Division of Medical Oncology, Department of Internal Medicine, University of Kansas Cancer Center, Kansas, USA.<br /><searchLink fieldCode="AU" term="%22Molina-Cerrillo+J%22">Molina-Cerrillo J</searchLink>; Department of Medical Oncology, Hospital Ramón y Cajal, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Kopecky+J%22">Kopecky J</searchLink>; Department of Clinical Oncology and Radiotherapy, University Hospital Hradec Kralove, Hradec Kralove, Czechia.<br /><searchLink fieldCode="AU" term="%22de+Liaño+AG%22">de Liaño AG</searchLink>; Medical Oncology Department, CHU Insular-Materno Infantil, Las Palmas, Spain.<br /><searchLink fieldCode="AU" term="%22Kucharz+J%22">Kucharz J</searchLink>; Department of Uro-Oncology, Maria Sklodowska-Curie National Research Institute of Oncology Warsaw, Warsaw, Poland.<br /><searchLink fieldCode="AU" term="%22Fiala+O%22">Fiala O</searchLink>; Department of Oncology and Radiotherapeutics, Faculty of Medicine and University Hospital in Pilsen, Charles University, Pilsen, Czech Republic.; Biomedical Center, Faculty of Medicine in Pilsen, Charles University, Pilsen, Czech Republic.<br /><searchLink fieldCode="AU" term="%22Matrana+MR%22">Matrana MR</searchLink>; Department of Internal Medicine, Hematology/Oncology, Ochsner Medical Center, New Orleans, LA, USA.<br /><searchLink fieldCode="AU" term="%22Kopp+RM%22">Kopp RM</searchLink>; Clinical Oncology, Sociedad de Oncología y Hematología del Cesar, Valledupar, Colombia.<br /><searchLink fieldCode="AU" term="%22Di+Civita+MA%22">Di Civita MA</searchLink>; Department of Radiological, Oncological and Pathological Sciences, Policlinico Umberto I, University of Rome, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Zgura+A%22">Zgura A</searchLink>; Department of Obstetrics-Radiotherapy, Alexandru Trestioreanu Institute of Oncology, 'Carol Davila' University of Medicine and Pharmacy, Prof. Dr, Bucharest, Romania.<br /><searchLink fieldCode="AU" term="%22Ansari+J%22">Ansari J</searchLink>; Medical Oncology, Tawam Hospital, Al Ain, UAE.<br /><searchLink fieldCode="AU" term="%22Kihnel+R%22">Kihnel R</searchLink>; Department of Internal Medicine, Hematology/Oncology, Ochsner Medical Center, New Orleans, LA, USA.<br /><searchLink fieldCode="AU" term="%22De+Felice+F%22">De Felice F</searchLink>; Radiation Oncology, Department of Radiological, AOU Policlinico Umberto I, Oncological and Pathological Sciences, 'Sapienza' University of Rome, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Angel+M%22">Angel M</searchLink>; Instituto Alexander Fleming, Ciudad De Buenos Aires, Argentina.<br /><searchLink fieldCode="AU" term="%22Monteiro+FSM%22">Monteiro FSM</searchLink>; Latin American Cooperative Oncology Group-LACOG, Porto Alegre, Brazil.; Oncology and Hematology Department, Hospital Sírio Libanês, Brasília, Brazil.<br /><searchLink fieldCode="AU" term="%22Soares+A%22">Soares A</searchLink>; Latin American Cooperative Oncology Group-LACOG, Porto Alegre, Brazil.; Oncology Unit, Hospital Israelita Albert Einstein, São Paulo, SP, Brazil.<br /><searchLink fieldCode="AU" term="%22Urun+Y%22">Urun Y</searchLink>; Department of Medical Oncology, Faculty of Medicine, Ankara University, 06620, Ankara, Turkey.<br /><searchLink fieldCode="AU" term="%22Buti+S%22">Buti S</searchLink>; Medical Oncology Unit, University Hospital of Parma, Parma, Italy.; Department of Medicine and Surgery, University of Parma, Parma, Italy.<br /><searchLink fieldCode="AU" term="%22Santini+D%22">Santini D</searchLink>; Department of Radiological, Oncological and Pathological Sciences, Policlinico Umberto I, University of Rome, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Santoni+M%22">Santoni M</searchLink>; Medical Oncology Unit, Macerata Hospital, Macerata, Italy.
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  Data: <searchLink fieldCode="JN" term="%228605732%22">Cancer immunology, immunotherapy : CII</searchLink> [Cancer Immunol Immunother] 2026 Mar 24; Vol. 75 (4). <i>Date of Electronic Publication: </i>2026 Mar 24.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Springer+Verlag%22">Springer Verlag </searchLink><i>Country of Publication: </i>Germany <i>NLM ID: </i>8605732 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1432-0851 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2203407004%22">03407004 </searchLink><i>NLM ISO Abbreviation: </i>Cancer Immunol Immunother <i>Subsets: </i>MEDLINE
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