Unveiling antibacterial and α-amylase inhibitory potentials of Opuntia ficus-indica aqueous extract through LC-ESI-MS/MS-guided in vitro and in silico investigation.

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Title: Unveiling antibacterial and α-amylase inhibitory potentials of Opuntia ficus-indica aqueous extract through LC-ESI-MS/MS-guided in vitro and in silico investigation.
Authors: Zaater A; Biodiversity Laboratory and Application of Biotechnology in Agriculture, Department of Agronomy, Faculty of Nature and Life Sciences, University of El Oued, El Oued, Algeria. Electronic address: abdelmalek-zaater@univ-eloued.dz., Touati S; Biodiversity Laboratory and Application of Biotechnology in Agriculture, Department of Agronomy, Faculty of Nature and Life Sciences, University of El Oued, El Oued, Algeria. Electronic address: touati-sara@univ-eloued.dz., Messaoudi M; Laboratory of Biology, Environment and Health, Department of Cellular and Molecular Biology, Faculty of Nature and Life Sciences, University of El Oued, El Oued, Algeria. Electronic address: messaoudi-mohammed@univ-eloued.dz., Lanez E; Laboratory of Valorization and Technology of Saharian Resources (VTRS), Department of Process Engineering and Petrochemistry, Faculty of Technology, University of El Oued, El Oued 39000, Algeria. Electronic address: touhami-lanez@univ-eloued.dz., Ahmed OZ; Laboratory of Biology, Environment and Health, Department of Cellular and Molecular Biology, Faculty of Nature and Life Sciences, University of El Oued, El Oued, Algeria. Electronic address: zouariahmed-ouafa@univ-eloued.dz., Benamor ML; Laboratory of Valorization and Technology of Saharian Resources (VTRS), Department of Process Engineering and Petrochemistry, Faculty of Technology, University of El Oued, El Oued 39000, Algeria., Abdelhameed TM; Department of Medical Nutrition, Faculty of Medical Technologies, University of Zawia, Zawia, Libya. Electronic address: taher.abdelhameed@zu.edu.ly., Adaika A; Laboratory of Valorization and Technology of Saharian Resources (VTRS), Department of Process Engineering and Petrochemistry, Faculty of Technology, University of El Oued, El Oued 39000, Algeria., Bekkar Y; Laboratory of Valorization and Technology of Saharian Resources (VTRS), Department of Process Engineering and Petrochemistry, Faculty of Technology, University of El Oued, El Oued 39000, Algeria. Electronic address: yahia-bekkar@univ-eloued.dz., Douidi AC; Laboratory of Valorization and Technology of Saharian Resources (VTRS), Department of Process Engineering and Petrochemistry, Faculty of Technology, University of El Oued, El Oued 39000, Algeria. Electronic address: douidi-ahmedchaouki@univ-eloued.dz., Bechki L; Laboratory of Valorization and Promotion of Saharan Resources (VPRS), Faculty of Mathematics and Material Sciences, Department of Chemistry, Kasdi Merbah University, Ouargla 30000, Algeria., Lanez T; Laboratory of Valorization and Technology of Saharian Resources (VTRS), Department of Process Engineering and Petrochemistry, Faculty of Technology, University of El Oued, El Oued 39000, Algeria. Electronic address: lanez-elhafnaoui@univ-eloued.dz., Neghmouche Nacer S; Laboratory of Valorization and Technology of Saharian Resources (VTRS), Department of Process Engineering and Petrochemistry, Faculty of Technology, University of El Oued, El Oued 39000, Algeria. Electronic address: neghmouchenacer-salah@univ-eloued.dz., Garzoli S; Department of Chemistry and Technologies of Drug, Sapienza University, P. le Aldo Moro, 5, 00185 Rome, Italy. Electronic address: stefania.garzoli@uniroma1.it.
Source: Bioorganic chemistry [Bioorg Chem] 2026 Jul 05; Vol. 175, pp. 109780. Date of Electronic Publication: 2026 Mar 19.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 1303703 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1090-2120 (Electronic) Linking ISSN: 00452068 NLM ISO Abbreviation: Bioorg Chem Subsets: MEDLINE
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  Data: Unveiling antibacterial and α-amylase inhibitory potentials of Opuntia ficus-indica aqueous extract through LC-ESI-MS/MS-guided in vitro and in silico investigation.
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  Data: <searchLink fieldCode="AU" term="%22Zaater+A%22">Zaater A</searchLink>; Biodiversity Laboratory and Application of Biotechnology in Agriculture, Department of Agronomy, Faculty of Nature and Life Sciences, University of El Oued, El Oued, Algeria. Electronic address: abdelmalek-zaater@univ-eloued.dz.<br /><searchLink fieldCode="AU" term="%22Touati+S%22">Touati S</searchLink>; Biodiversity Laboratory and Application of Biotechnology in Agriculture, Department of Agronomy, Faculty of Nature and Life Sciences, University of El Oued, El Oued, Algeria. Electronic address: touati-sara@univ-eloued.dz.<br /><searchLink fieldCode="AU" term="%22Messaoudi+M%22">Messaoudi M</searchLink>; Laboratory of Biology, Environment and Health, Department of Cellular and Molecular Biology, Faculty of Nature and Life Sciences, University of El Oued, El Oued, Algeria. Electronic address: messaoudi-mohammed@univ-eloued.dz.<br /><searchLink fieldCode="AU" term="%22Lanez+E%22">Lanez E</searchLink>; Laboratory of Valorization and Technology of Saharian Resources (VTRS), Department of Process Engineering and Petrochemistry, Faculty of Technology, University of El Oued, El Oued 39000, Algeria. Electronic address: touhami-lanez@univ-eloued.dz.<br /><searchLink fieldCode="AU" term="%22Ahmed+OZ%22">Ahmed OZ</searchLink>; Laboratory of Biology, Environment and Health, Department of Cellular and Molecular Biology, Faculty of Nature and Life Sciences, University of El Oued, El Oued, Algeria. Electronic address: zouariahmed-ouafa@univ-eloued.dz.<br /><searchLink fieldCode="AU" term="%22Benamor+ML%22">Benamor ML</searchLink>; Laboratory of Valorization and Technology of Saharian Resources (VTRS), Department of Process Engineering and Petrochemistry, Faculty of Technology, University of El Oued, El Oued 39000, Algeria.<br /><searchLink fieldCode="AU" term="%22Abdelhameed+TM%22">Abdelhameed TM</searchLink>; Department of Medical Nutrition, Faculty of Medical Technologies, University of Zawia, Zawia, Libya. Electronic address: taher.abdelhameed@zu.edu.ly.<br /><searchLink fieldCode="AU" term="%22Adaika+A%22">Adaika A</searchLink>; Laboratory of Valorization and Technology of Saharian Resources (VTRS), Department of Process Engineering and Petrochemistry, Faculty of Technology, University of El Oued, El Oued 39000, Algeria.<br /><searchLink fieldCode="AU" term="%22Bekkar+Y%22">Bekkar Y</searchLink>; Laboratory of Valorization and Technology of Saharian Resources (VTRS), Department of Process Engineering and Petrochemistry, Faculty of Technology, University of El Oued, El Oued 39000, Algeria. Electronic address: yahia-bekkar@univ-eloued.dz.<br /><searchLink fieldCode="AU" term="%22Douidi+AC%22">Douidi AC</searchLink>; Laboratory of Valorization and Technology of Saharian Resources (VTRS), Department of Process Engineering and Petrochemistry, Faculty of Technology, University of El Oued, El Oued 39000, Algeria. Electronic address: douidi-ahmedchaouki@univ-eloued.dz.<br /><searchLink fieldCode="AU" term="%22Bechki+L%22">Bechki L</searchLink>; Laboratory of Valorization and Promotion of Saharan Resources (VPRS), Faculty of Mathematics and Material Sciences, Department of Chemistry, Kasdi Merbah University, Ouargla 30000, Algeria.<br /><searchLink fieldCode="AU" term="%22Lanez+T%22">Lanez T</searchLink>; Laboratory of Valorization and Technology of Saharian Resources (VTRS), Department of Process Engineering and Petrochemistry, Faculty of Technology, University of El Oued, El Oued 39000, Algeria. Electronic address: lanez-elhafnaoui@univ-eloued.dz.<br /><searchLink fieldCode="AU" term="%22Neghmouche+Nacer+S%22">Neghmouche Nacer S</searchLink>; Laboratory of Valorization and Technology of Saharian Resources (VTRS), Department of Process Engineering and Petrochemistry, Faculty of Technology, University of El Oued, El Oued 39000, Algeria. Electronic address: neghmouchenacer-salah@univ-eloued.dz.<br /><searchLink fieldCode="AU" term="%22Garzoli+S%22">Garzoli S</searchLink>; Department of Chemistry and Technologies of Drug, Sapienza University, P. le Aldo Moro, 5, 00185 Rome, Italy. Electronic address: stefania.garzoli@uniroma1.it.
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  Data: <searchLink fieldCode="JN" term="%221303703%22">Bioorganic chemistry</searchLink> [Bioorg Chem] 2026 Jul 05; Vol. 175, pp. 109780. <i>Date of Electronic Publication: </i>2026 Mar 19.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier%22">Elsevier </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>1303703 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1090-2120 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200452068%22">00452068 </searchLink><i>NLM ISO Abbreviation: </i>Bioorg Chem <i>Subsets: </i>MEDLINE
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        Value: 10.1016/j.bioorg.2026.109780
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        Text: English
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