Cohort profile: the Mendelian randomisation in pregnancy (MR-PREG) collaboration - improving evidence for prevention and treatment of adverse pregnancy and perinatal outcomes.

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Title: Cohort profile: the Mendelian randomisation in pregnancy (MR-PREG) collaboration - improving evidence for prevention and treatment of adverse pregnancy and perinatal outcomes.
Authors: McBride N; MRC Integrative Epidemiology Unit at the University of Bristol, Bristol, UK.; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK., Clayton GL; MRC Integrative Epidemiology Unit at the University of Bristol, Bristol, UK gemma.clayton@bristol.ac.uk.; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK., Goncalves Soares A; MRC Integrative Epidemiology Unit at the University of Bristol, Bristol, UK.; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK., Yang Q; MRC Integrative Epidemiology Unit at the University of Bristol, Bristol, UK.; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.; Department of Endocrine and Metabolic Diseases, Shanghai Institute of Endocrine and Metabolic Diseases, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.; Shanghai National Clinical Research Center for Metabolic Diseases, Key Laboratory for Endocrine and Metabolic Diseases of the National Health Commission of the PR China, Shanghai Key Laboratory for Endocrine Tumor, Lifecycle Health Management Center, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China., Bond TA; MRC Integrative Epidemiology Unit at the University of Bristol, Bristol, UK.; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.; Frazer Institute, University of Queensland, Woolloongabba, Queensland, Australia., Taylor A; MRC Integrative Epidemiology Unit at the University of Bristol, Bristol, UK.; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.; Division of Surgery and Interventional Science, University College London, London, UK., Chatzigeorgiou C; MRC Integrative Epidemiology Unit at the University of Bristol, Bristol, UK.; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK., Aiton E; MRC Integrative Epidemiology Unit at the University of Bristol, Bristol, UK.; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK., West J; Population Health, School of Medicine and Population Health, University of Sheffield, Sheffield, UK.; Bradford Institute for Health Research, Bradford Teaching Hospitals, Bradford, UK., Magnus MC; Centre for Fertility and Health, Norwegian Institute of Public Health, Oslo, Norway., Lawlor DA; MRC Integrative Epidemiology Unit at the University of Bristol, Bristol, UK.; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK., Borges MC; MRC Integrative Epidemiology Unit at the University of Bristol, Bristol, UK.; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.
Source: BMJ open [BMJ Open] 2026 Mar 24; Vol. 16 (3), pp. e103753. Date of Electronic Publication: 2026 Mar 24.
Publication Type: Journal Article
Journal Info: Publisher: BMJ Publishing Group Ltd Country of Publication: England NLM ID: 101552874 Publication Model: Electronic Cited Medium: Internet ISSN: 2044-6055 (Electronic) Linking ISSN: 20446055 NLM ISO Abbreviation: BMJ Open Subsets: MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22McBride+N%22">McBride N</searchLink>; MRC Integrative Epidemiology Unit at the University of Bristol, Bristol, UK.; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.<br /><searchLink fieldCode="AU" term="%22Clayton+GL%22">Clayton GL</searchLink>; MRC Integrative Epidemiology Unit at the University of Bristol, Bristol, UK gemma.clayton@bristol.ac.uk.; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.<br /><searchLink fieldCode="AU" term="%22Goncalves+Soares+A%22">Goncalves Soares A</searchLink>; MRC Integrative Epidemiology Unit at the University of Bristol, Bristol, UK.; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.<br /><searchLink fieldCode="AU" term="%22Yang+Q%22">Yang Q</searchLink>; MRC Integrative Epidemiology Unit at the University of Bristol, Bristol, UK.; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.; Department of Endocrine and Metabolic Diseases, Shanghai Institute of Endocrine and Metabolic Diseases, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.; Shanghai National Clinical Research Center for Metabolic Diseases, Key Laboratory for Endocrine and Metabolic Diseases of the National Health Commission of the PR China, Shanghai Key Laboratory for Endocrine Tumor, Lifecycle Health Management Center, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Bond+TA%22">Bond TA</searchLink>; MRC Integrative Epidemiology Unit at the University of Bristol, Bristol, UK.; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.; Frazer Institute, University of Queensland, Woolloongabba, Queensland, Australia.<br /><searchLink fieldCode="AU" term="%22Taylor+A%22">Taylor A</searchLink>; MRC Integrative Epidemiology Unit at the University of Bristol, Bristol, UK.; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.; Division of Surgery and Interventional Science, University College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Chatzigeorgiou+C%22">Chatzigeorgiou C</searchLink>; MRC Integrative Epidemiology Unit at the University of Bristol, Bristol, UK.; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.<br /><searchLink fieldCode="AU" term="%22Aiton+E%22">Aiton E</searchLink>; MRC Integrative Epidemiology Unit at the University of Bristol, Bristol, UK.; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.<br /><searchLink fieldCode="AU" term="%22West+J%22">West J</searchLink>; Population Health, School of Medicine and Population Health, University of Sheffield, Sheffield, UK.; Bradford Institute for Health Research, Bradford Teaching Hospitals, Bradford, UK.<br /><searchLink fieldCode="AU" term="%22Magnus+MC%22">Magnus MC</searchLink>; Centre for Fertility and Health, Norwegian Institute of Public Health, Oslo, Norway.<br /><searchLink fieldCode="AU" term="%22Lawlor+DA%22">Lawlor DA</searchLink>; MRC Integrative Epidemiology Unit at the University of Bristol, Bristol, UK.; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.<br /><searchLink fieldCode="AU" term="%22Borges+MC%22">Borges MC</searchLink>; MRC Integrative Epidemiology Unit at the University of Bristol, Bristol, UK.; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.
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